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Surgical revascularization for patients with diabetes: Do all roads lead to Rome?
The BARI 2D trial (Bypass Angioplasty Revascularization Investigation 2 Diabetes Trial)1 randomly allocated patients with type 2 diabetes and stable coronary artery disease (CAD) and evidence of myocardial ischemia to undergo, at the discretion of the treating physician, either early revascularization with a percutaneous intervention (PCI) or coronary artery bypass grafting (CABG) with optimal medical therapy (OMT), or OMT alone. Patients in the OMT group were also randomly assigned to insulin-sensitizing strategy (metformin and thiazolidinedione) or an insulin-providing strategy (insulin or secretagogue.) The 5-year follo...
Source: The Journal of Thoracic and Cardiovascular Surgery - August 28, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Tomas A. Salerno Tags: Editorial commentary Source Type: research

Safety and efficacy of glucose-insulin-potassium treatment in coronary artery bypass graft surgery and percutaneous coronary intervention
The purpose of this meta-analysis was to evaluate protective effects of glucose–insulin–potassium (GIK) on outcomes after coronary artery bypass grafting (CABG) or percutaneous coronary intervention (PCI). We systematically searched Medline/Pubmed, Elsevier, Embase, Web of Knowledge and Google Scholar. A total of 1206 studies were retrieved during the extensive literature search of all major databases; however, 38 trials reporting the end-point of interest were selected. We performed a pooled analysis of outcomes following PCI: incidence of cardiac arrest [odds ratio (OR) of 0.91; 95% confidence interval (CI): ...
Source: Interactive CardioVascular and Thoracic Surgery - October 19, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Ali-Hassan-Sayegh, S., Mirhosseini, S. J., Zeriouh, M., Dehghan, A. M., Shahidzadeh, A., Karimi-Bondarabadi, A. A., Sabashnikov, A., Popov, A.-F. Tags: Congestive Heart Failure Adult Cardiac Source Type: research

Clinical events beyond one year after an acute coronary syndrome: insights from the RECLOSE 2-ACS study.
CONCLUSIONS: Patients at risk of adverse events beyond 12 months after an ACS may be identified by simple clinical and angiographic characteristics such as age, diabetes, chronic kidney disease, prior MI and multivessel CAD. The risk of adverse events progressively increases with the number of these high-risk features. PMID: 28317790 [PubMed - in process]
Source: EuroIntervention - March 23, 2017 Category: Cardiovascular & Thoracic Surgery Tags: EuroIntervention Source Type: research