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Drug: Docetaxel
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Decreased Expression of HN1 Sensitizes Prostate Cancer Cells to Apoptosis Induced by Docetaxel and 2-Methoxyestradiol
CONCLUSION: HN1 is an anti-apoptotic molecule and inhibits Docetaxel and 2-Methoxyestradiol induced apoptosis by targeting Cyclin B1.PMID:35414498
Source: Annals of Clinical and Laboratory Science - April 13, 2022 Category: Laboratory Medicine Authors: Lokman Varisli Source Type: research
Interventions for the treatment of oral cavity and oropharyngeal cancer: chemotherapy
CONCLUSIONS: The results of this review demonstrate that chemotherapy in the curative-intent treatment of oral cavity and oropharyngeal cancers only seems to be of benefit when used in specific circumstances together with locoregional treatment. The evidence does not show a clear survival benefit from the use of induction chemotherapy prior to radiotherapy, surgery or CRT. Adjuvant CRT reduces the risk of death by 16%, as compared to radiotherapy alone. Concurrent chemoradiation as compared to radiation alone is associated with a greater than 20% improvement in overall survival; however, additional research is required to ...
Source: Cancer Control - December 20, 2021 Category: Cancer & Oncology Authors: Ambika Parmar Michaelina Macluskey Niall Mc Goldrick David I Conway Anne-Marie Glenny Janet E Clarkson Helen V Worthington Kelvin Kw Chan Source Type: research
