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Efficacy of Antiplatelet Therapy in Secondary Prevention Following Lacunar Stroke: Pooled Analysis of Randomized Trials Clinical Sciences
Conclusions— Our results suggest that any of the single antiplatelet agents compared with placebo in the included trials is adequate for secondary stroke prevention after lacunar stroke. Dual antiplatelet therapy should not be used for long-term stroke prevention in this stroke subtype.
Source: Stroke - March 23, 2015 Category: Neurology Authors: Kwok, C. S., Shoamanesh, A., Copley, H. C., Myint, P. K., Loke, Y. K., Benavente, O. R. Tags: Antiplatelets Clinical Sciences Source Type: research

Age-Related Decline in Oligodendrogenesis Retards White Matter Repair in Mice Basic Sciences
Conclusions— An age-related decline in cyclic AMP response element-binding protein–mediated oligodendrogenesis may compromise endogenous white matter repair mechanisms, and therefore, drugs that activate cyclic AMP response element-binding protein signaling provide a potential therapeutic approach for treating white matter injury in aging brains.
Source: Stroke - August 26, 2013 Category: Neurology Authors: Miyamoto, N., Pham, L.-D. D., Hayakawa, K., Matsuzaki, T., Seo, J. H., Magnain, C., Ayata, C., Kim, K.-W., Boas, D., Lo, E. H., Arai, K. Tags: Animal models of human disease, Other Stroke Treatment - Medical, Other Vascular biology Basic Sciences Source Type: research