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Long non ‑coding RNA LINC01960‑201 hinders decidualization of endometrial stromal cell in endometriosis: Relevance to endometrial receptivity
In conclusion, it was hypothesized that LINC01960‑201 played a notable regulatory role in the decidualization of endometrial stromal cells in women with endometriosis during the window of implantation, and its abnormal expression may lead to the decline of endometrial receptivity and recurrent abortions.PMID:36281935 | DOI:10.3892/mmr.2022.12883
Source: Molecular Medicine - October 25, 2022 Category: Molecular Biology Authors: Han Cai Jinghe Lang Source Type: research

Matrix Metalloproteinases in Human Decidualized Endometrial Stromal Cells
Curr Issues Mol Biol. 2021 Nov 26;43(3):2111-2123. doi: 10.3390/cimb43030146.ABSTRACTCyclic changes, such as growth, decidualization, shedding, and regeneration, in the human endometrium are regulated by the reciprocal action of female hormones, such as estradiol (E2), and progesterone (P4). Matrix metalloproteases (MMPs) and tissue inhibitors of MMPs (TIMPs) control the invasion of extravillous trophoblast cells after implantation. Several MMPs and TIMPs function in the decidua and endometrial stromal cells (ESCs). Here, we aimed to systematically investigate the changes in MMPs and TIMPs associated with ESC decidualizati...
Source: Current Issues in Molecular Biology - December 23, 2021 Category: Molecular Biology Authors: Yoji Hisamatsu Hiromi Murata Hiroaki Tsubokura Yoshiko Hashimoto Masaaki Kitada Susumu Tanaka Hidetaka Okada Source Type: research

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