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Infectious Disease: Hepatitis B
Drug: Polyethylene Glycol

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Total 17 results found since Jan 2013.

Avian anti-HBV immunoglobulin: New tool to improve hepatitis B diagnosis methods
In conclusion, it was possible producing anti-HBs IgY by immunizing chickens with HBV vaccine; this molecule could be used as capture antibody to help detecting HBsAg in-house ELISA.PMID:37659497 | DOI:10.1016/j.ijbiomac.2023.126644
Source: International Journal of Biological Macromolecules - September 2, 2023 Category: Biochemistry Authors: Raissa Martins Deodato Debora Regina Lopes Dos Santos Mayara Torquato Lima da Silva Helena Medina Cruz Vanessa Salete de Paula Livia Melo Villar Source Type: research

Analysis of hepatocellular carcinoma associated with hepatitis B virus
J Cell Mol Med. 2023 Jul 30. doi: 10.1111/jcmm.17867. Online ahead of print.ABSTRACTThe hepatitis B virus (HBV) is considered one of the main driving forces in the development of hepatocellular carcinoma (HCC). Human HBV is a partially double-stranded DNA (dsDNA) virus consisting of approximately 3.2 kbp. HBV predominantly infects hepatocytes via the receptor sodium taurocholate cotransporting polypeptide (NTCP) and coreceptor hepatic proteoglycan. The replication of HBV in hepatocytes leads to apoptosis while simultaneously leading to cirrhosis and cancer. Although the integration of dsDNA into the hepatocyte genome seems...
Source: J Cell Mol Med - July 30, 2023 Category: Molecular Biology Authors: Litao Zheng Source Type: research

Increased suicidal erythrocyte death in patients with hepatitis B-related acute-on-chronic liver failure
Am J Physiol Gastrointest Liver Physiol. 2022 Apr 12. doi: 10.1152/ajpgi.00050.2020. Online ahead of print.ABSTRACTAnemia is a common complication of hepatitis B-related acute-on-chronic liver failure (HB-ACLF). Eryptosis, a suicidal erythrocyte death characterized by phosphatidylserine (PS) externalization and red blood cell-derived microparticle (RMP) generation, decreases erythrocyte lifespan. Herein, we investigated whether enhanced eryptosis is involved in the anemia pathophysiology associated with HB-ACLF. PS exposure, cell volume, cytosolic Ca2+, and reactive oxygen species (ROS) production were determined using flo...
Source: American Journal of Physiology. Gastrointestinal and Liver Physiology - April 12, 2022 Category: Physiology Authors: Cheng Mei Fang Peng Wenyu Yin Wei Xu Run Yao Bijuan Li Rongrong Zhou Xuegong Fan Ning Li Source Type: research