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Specialty: Hematology
Drug: Aspirin

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Total 155 results found since Jan 2013.

Geriatric patient with neurological symptoms and prolonged aPTT
Inn Med (Heidelb). 2023 Sep 20. doi: 10.1007/s00108-023-01581-3. Online ahead of print.ABSTRACTA 73-year-old man with dementia was referred to our clinic with hypernatremia and volume depletion. New-onset neurogenic dysphagia was likely the reason for both. The patient had chronic embolic strokes on the computed tomography (CT) images. Documentation from previous hospitalizations in different hospitals revealed a repeatedly prolonged activated partial thromboplastin time (aPTT); 5 years prior, antiphospholipid antibody syndrome had already been suspected, but the necessary workup was never completed. We diagnosed the patie...
Source: Hamostaseologie - September 20, 2023 Category: Hematology Authors: Aisuluu Atakanova Anne Heiligers Martin Kirschner Cornelius Bollheimer Susanne Fleig Source Type: research

Platelets and neutrophils cooperate to induce increased NETosis in JAK2V617F myeloproliferative neoplasms
CONCLUSIONS: Our study demonstrates that JAK2V617F neutrophils alone are not sufficient to promote thrombosis; rather, platelets cooperate with neutrophils to promote NETosis in vivo. A new role for aspirin in thrombosis prevention in MPNs was also identified.PMID:37678548 | DOI:10.1016/j.jtha.2023.08.028
Source: Thrombosis and Haemostasis - September 7, 2023 Category: Hematology Authors: Alexandre Guy Geoffrey Garcia Virginie Gourdou-Latyszenok Laura Wolff-Thrombini Lara Josserand Quentin Kimmerlin Simon Favre Badr Kilani Caroline Marty Yacine Boulaftali Sylvie Labrouche-Colomer Olivier Mansier Chlo é James Source Type: research

Serotonin secretion by blood platelets: accuracy of high-performance liquid chromatography-electrochemical technique compared with the isotopic test and use in a clinical laboratory
CONCLUSION: HPLC-ECD assay for platelet serotonin secretion is highly accurate, has advantages over the reference 3H-5-HT test, and is suitable as a clinical laboratory technique.PMID:37601022 | PMC:PMC10439442 | DOI:10.1016/j.rpth.2023.102156
Source: Thrombosis and Haemostasis - August 21, 2023 Category: Hematology Authors: Eduardo Aranda Seiki Iha Sandra Solari David Rodr íguez Viviana Romero Luis Villarroel Jaime Pereira Olga Panes Diego Mezzano Source Type: research

The effect of thrombocytapheresis on hemogram and biochemistry parameters in patients with essential thrombocytemia
CONCLUSION: The use of thrombocytapheresıs in patients with essential thrombocytosis causes a rapid decrease in platelet values as well as an effect on hemogram and biochemistry parameters. Other hemogram and biochemistry parameters such as platelet value should be monitored in patients.PMID:37558046 | DOI:10.1016/j.tracli.2023.08.001
Source: Transfusion Clinique et Biologique - August 9, 2023 Category: Hematology Authors: Ahmet Kaya İrfan Kuku Mehmet Ali Erkurt Emin Kaya İlhami Berber Soykan Bi çim Emine Hidayet Salih C ırık S üleyman Arslan Fatma Hilal Ya ğin Ahmet Sar ıcı Source Type: research

The effect of thrombocytapheresis on hemogram and biochemistry parameters in patients with essential thrombocytemia
CONCLUSION: The use of thrombocytapheresıs in patients with essential thrombocytosis causes a rapid decrease in platelet values as well as an effect on hemogram and biochemistry parameters. Other hemogram and biochemistry parameters such as platelet value should be monitored in patients.PMID:37558046 | DOI:10.1016/j.tracli.2023.08.001
Source: Transfusion Clinique et Biologique - August 9, 2023 Category: Hematology Authors: Ahmet Kaya İrfan Kuku Mehmet Ali Erkurt Emin Kaya İlhami Berber Soykan Bi çim Emine Hidayet Salih C ırık S üleyman Arslan Fatma Hilal Ya ğin Ahmet Sar ıcı Source Type: research

Amplified inhibition of atherosclerotic plaque-induced platelet activation by glenzocimab with dual antiplatelet therapy
CONCLUSIONS: Addition of glenzocimab to aspirin and ticagrelor enhances platelet inhibition via multiple mechanisms of atherothrombosis. Compared to a GPIIb/IIIa inhibitor, glenzocimab shares multiple antithrombotic effects, with less inhibition of mechanisms involved in general haemostasis.PMID:37541591 | DOI:10.1016/j.jtha.2023.07.018
Source: Thrombosis and Haemostasis - August 4, 2023 Category: Hematology Authors: Fawaz O Alenazy Maan H Harbi Dean P Kavanagh Joshua Price Paul Brady Oscar Hargreaves Paul Harrison Alexandre Slater Alok Tiwari Phillip L R Nicolson Derek L Connolly Paulus Kirchhof Neena Kalia Martine Jandrot-Perrus Pierre H Mangin Steve P Watson Mark R Source Type: research

Warfarin faring better: Vitamin K antagonists beat rivaroxaban and apixaban in the INVICTUS and PROACT Xa trials
J Thromb Haemost. 2023 Jul 8:S1538-7836(23)00523-8. doi: 10.1016/j.jtha.2023.06.036. Online ahead of print.ABSTRACTAlthough guidelines give preference to the direct oral anticoagulants (DOACs) over vitamin K antagonists (VKAs) for stroke prevention in most patients with atrial fibrillation (AF), DOACs are not recommended in those with rheumatic heart disease or mechanical heart valves. The results of the INVICTUS trial (Investigation of Rheumatic AF Treatment Using Vitamin K Antagonists, Rivaroxaban or Aspirin Studies), which compared rivaroxaban with a VKA in patients with rheumatic heart disease associated AF, and the PR...
Source: Thrombosis and Haemostasis - July 10, 2023 Category: Hematology Authors: John W Eikelboom Jeffrey I Weitz Source Type: research

A randomised controlled trial to investigate the use of acute coronary syndrome therapy in patients hospitalised with covid-19: the c19-acs trial
CONCLUSIONS: Acute coronary syndrome treatment regimen was associated with a reduction in the length of hospital stay without an excess in major bleeding. A larger trial is needed to evaluate mortality.PMID:37230416 | PMC:PMC10204350 | DOI:10.1016/j.jtha.2023.04.045
Source: Thrombosis and Haemostasis - May 25, 2023 Category: Hematology Authors: Prapa Kanagaratnam Darrel P Francis Daniel Chamie Clare Coyle Alena Marynina George Katritsis Patricia Paiva Matyas Szigeti Graham Cole David de Andrade Nunes James Howard Rodrigo Esper Masood Khan Ranjit More Guilherme Barreto Rafael Meneguz-Moreno Ahran Source Type: research

A randomised controlled trial to investigate the use of acute coronary syndrome therapy in patients hospitalised with covid-19: the c19-acs trial
CONCLUSIONS: Acute coronary syndrome treatment regimen was associated with a reduction in the length of hospital stay without an excess in major bleeding. A larger trial is needed to evaluate mortality.PMID:37230416 | DOI:10.1016/j.jtha.2023.04.045
Source: Thrombosis and Haemostasis - May 25, 2023 Category: Hematology Authors: Prapa Kanagaratnam Darrel P Francis Daniel Chamie Clare Coyle Alena Marynina George Katritsis Patricia Paiva Matyas Szigeti Graham Cole David de Andrade Nunes James Howard Rodrigo Esper Masood Khan Ranjit More Guilherme Barreto Rafael Meneguz-Moreno Ahran Source Type: research

Switching from dual antiplatelet therapy with aspirin plus a P2Y12 inhibitor to dual pathway inhibition with aspirin plus vascular-dose rivaroxaban
CONCLUSION: In patients with CCS, switching from different DAPT regimens to DPI was feasible, showing enhanced P2Y12 inhibition with DAPT and reduced TG with DPI, with no differences in platelet-mediated global thrombogenicity between DPI and ticagrelor- and prasugrel, but not clopidogrel-, based DAPT.PMID:37224883 | DOI:10.1055/a-2098-6639
Source: Thrombosis and Haemostasis - May 24, 2023 Category: Hematology Authors: Luis Ortega-Paz Francesco Franchi Fabiana Rollini Mattia Galli Latonya Been Ghussan Ghanem Awss Shalhoub Tiffany Ossi Andrea Rivas Xuan Zhou Andres M Pineda Maldonado Siva Suryadevara Daniel Soffer Martin M Zenni Lisa K Jennings Dominick Angiolillo Source Type: research