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Fight Aging! Newsletter, April 11th 2022
In conclusion, plasma levels of IGHA2, APOA and HPT are associated with subclinical atherosclerosis independently of traditional risk factors and offers potential to predict this disease. The panel could improve primary prevention strategies in areas where imaging is not available. A Lesser Diversity of Circulating Antibodies in the Aging Killifish Immune System https://www.fightaging.org/archives/2022/04/a-lesser-diversity-of-circulating-antibodies-in-the-aging-killifish-immune-system/ Short-lived killifish are one of the more recently adopted animal models of aging. All such models are a trade-off betw...
Source: Fight Aging! - April 10, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Arguing for More, and More Rigorous, Drug Repurposing Efforts to Slow Aging
The authors of today's open access paper argue for much greater effort to be directed towards the repurposing of existing drugs with the goal of slowing aging. I have mixed feelings about the prevalence of drug repurposing in the pharmaceutical industry. The FDA makes it so very expensive to introduce any new drug that industry of course responds to the incentives and spends a great deal of time digging through the existing library of approved drugs in search of those that can be used in different circumstances. It is a great deal easier to take a drug with established safety data and seek approval for a new use than it is...
Source: Fight Aging! - April 7, 2022 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Fight Aging! Newsletter, April 4th 2022
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - April 3, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Preoperative evaluation of coagulation status in neuromodulation patients
CONCLUSIONS: New anticoagulants and antiplatelet medications are not monitored with PT/PTT, but they affect coagulation status and laboratory values. Although platelet function tests aid in a subset of medications, it is more difficult to assess the coagulation status of patients receiving novel anticoagulants. PT/PTT may provide value preoperatively.PMID:34826810 | DOI:10.3171/2021.8.JNS211509
Source: Journal of Neurosurgery - November 26, 2021 Category: Neurosurgery Authors: Amir Hadanny Zachary T Olmsted Anthony M Marchese Kyle Kroll Christopher Figueroa Thomas Tagney Jennifer Tram Marisa DiMarzio Olga Khazen Dorothy Mitchell Theodore Cangero Vishad Sukul Julie G Pilitsis Source Type: research

How are hospitals supposed to reduce readmissions? Part II
By KIP SULLIVAN, JD The notion that hospitals can reduce readmissions, and that punishing them for “excess” readmissions will get them to do that, became conventional wisdom during the 2000s on the basis of very little evidence. The Medicare Payment Advisory Commission (MedPAC) urged Congress to enact the Hospital Readmissions Reduction Program (HRRP) beginning in 2007, and in 2010 Congress did so. State Medicaid programs and private insurers quickly adopted similar programs. The rapid adoption of readmission-penalty programs without evidence confirming they can work has created widespread concern that these prog...
Source: The Health Care Blog - October 1, 2019 Category: Consumer Health News Authors: Christina Liu Tags: Health Policy CMS hospital readmissions Hospital Readmissions Reduction Program HRRP Kip Sullivan MedPAC Source Type: blogs

Health Care ’s Pigs and Pokes
By ROBERT MCNUTT, MD & NORTIN HADLER, MD Take the example of a middle-aged woman undergoing chemotherapy for breast cancer. Month after month she receives a bill for $16,000. This purchases a monthly infusion of one chemotherapeutic agent.  Much of the bill is paid by her insurance, but her personal checking account will cough up about $1000 per month until she pays down her deductible. The invoice, however, is an illusion. The amount is not the actual number of dollars required to pay for services and materials rendered. Most of the money is diverted in accordance with contractual agreements between the hospital and ...
Source: The Health Care Blog - March 18, 2018 Category: Consumer Health News Authors: John Irvine Tags: Uncategorized Source Type: blogs

On the Non-Effectiveness of Cost Effectiveness Analyses
By ROBERT MCNUTT, MD & NORTIN HADLER, MD Take the example of a middle-aged woman undergoing chemotherapy for breast cancer. Month after month she receives a bill for $16,000. This purchases a monthly infusion of one chemotherapeutic agent.  Much of the bill is paid by her insurance, but her personal checking account will cough up about $1000 per month until she pays down her deductible. The invoice, however, is an illusion. The amount is not the actual number of dollars required to pay for services and materials rendered. Most of the money is diverted in accordance with contractual agreements between the hospital and ...
Source: The Health Care Blog - March 18, 2018 Category: Consumer Health News Authors: John Irvine Tags: Uncategorized Source Type: blogs

The Smoking Gun: How U.S. Health Care Came to Cost Insanely More
By JOE FLOWER Cost is the big factor. Cost is why we can’t have nice things. The overwhelmingly vast pile of money we siphon into health care in the United States every year is the underlying driver of almost every other problem with health care in the United States from lack of access to waste to fragmentation to poor quality. We can’t afford to fix the problems, cover everyone, do real outreach, build IT systems that are interoperable and transparent and doc-friendly — or so it seems, because at least on weak examination every fix seems to add even more cost. And in the old ways of doing things in health care, the ...
Source: The Health Care Blog - May 27, 2015 Category: Consumer Health News Authors: John Irvine Tags: THCB Source Type: blogs

What is Life Coaching?
If you were to stop 100 people in the street and ask them what life is, you would probably get some strange looks, but I would imagine everybody would be able to give you an answer of some description. If you had too much time on your hands and you were to follow that up by asking them if they knew what a coach was, again most would be able to give you a satisfactory answer. So why do you think it is, that if you stopped 100 people and asked them to explain what Life Coaching is you would get more blank stares than if you asked the way to the gym at a Star Trek convention? You cannot get too many more obvious words than, ...
Source: Life Coach Blog: The Discomfort Zone : - February 25, 2014 Category: Life Coaches Authors: Tim Brownson Tags: Life Coaching Source Type: blogs

CMS Adds Quality Measures to Physician Compare Website for Some Group Practices and ACO’s
The Centers for Medicare & Medicaid Services (CMS) announced that for the first time, quality measures have been added to Physician Compare, a website that helps consumers search for information about hundreds of thousands of physicians and other health care professionals. "Patients and their families need facts to help them in making important decisions about health care, and choosing the right physician is one of the most important decisions they face," said CMS Administrator Marilyn Tavenner. In the first year, 66 group practices and 141 Accountable Care Organizations (ACO) now have quality data publicly reporte...
Source: Policy and Medicine - February 24, 2014 Category: Health Medicine and Bioethics Commentators Authors: Thomas Sullivan Source Type: blogs