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An examination of care received by women with recurrent miscarriage and infertility against guideline-based key performance indicators
CONCLUSIONS: Women with RM and infertility received care largely in line with RM guideline-based KPIs. However, we identified areas for improvement, including the quality of information provision, and access to certain investigations. While guideline-based KPIs allow for internationally applicable and reproducible audit that can direct service improvements, the experiences and needs of service-users are not captured, meriting further qualitative research.PMID:36621261 | DOI:10.1016/j.ejogrb.2023.01.002
Source: Reproductive Biology - January 9, 2023 Category: Reproduction Medicine Authors: Laura Linehan Marita Hennessy Keelin O'Donoghue Source Type: research

Clinician engagement in the ADAPTABLE (Aspirin Dosing: A Patient-centric Trial Assessing Benefits and Long-Term Effectiveness) trial
CONCLUSION: Maximizing clinician engagement is important for the success of clinical trials; the strategies employed in the ADAPTABLE trial may serve as a template for future pragmatic studies.PMID:33541120 | DOI:10.1177/1740774520988838
Source: Clinical Trials - February 5, 2021 Category: Research Authors: Ajar Kochar Mary B Summers Catherine P Benziger Guillaume Marquis-Gravel Darren A DeWalt Carl J Pepine Kamal Gupta Steven M Bradley John A Dodson Brent C Lampert Holly Robertson Tamar S Polonsky W Schuyler Jones Mark B Effron Source Type: research

Paying for Performance Improvement in Quality and Outcomes of Cardiovascular Care: Challenges and Prospects
Methodist Debakey Cardiovasc J. 2020 Jul-Sep;16(3):225-231. doi: 10.14797/mdcj-16-3-225.ABSTRACTOver the past two decades, Medicare and other payers have been looking at ways to base payment for cardiovascular care on the quality and outcomes of care delivered. Public reporting of hospital performance on a series of quality measures began in 2004 with basic processes of care such as aspirin use and influenza vaccination, and it expanded in later years to include outcomes such as mortality and readmission rates. Following the passage of the Affordable Care Act in March 2010, Medicare and other payers moved forward with pay-...
Source: Methodist DeBakey Cardiovascular Journal - November 2, 2020 Category: Cardiology Authors: Mustafa Husaini Karen E Joynt Maddox Source Type: research

Informatics and Computational Methods in Natural Product Drug Discovery: A Review and Perspectives
Joseph D. Romano1,2,3,4 and Nicholas P. Tatonetti1,2,3,4* 1Department of Biomedical Informatics, Columbia University, New York, NY, United States 2Department of Systems Biology, Columbia University, New York, NY, United States 3Department of Medicine, Columbia University, New York, NY, United States 4Data Science Institute, Columbia University, New York, NY, United States The discovery of new pharmaceutical drugs is one of the preeminent tasks—scientifically, economically, and socially—in biomedical research. Advances in informatics and computational biology have increased productivity at many ...
Source: Frontiers in Genetics - April 29, 2019 Category: Genetics & Stem Cells Source Type: research

Health Care ’s Pigs and Pokes
By ROBERT MCNUTT, MD & NORTIN HADLER, MD Take the example of a middle-aged woman undergoing chemotherapy for breast cancer. Month after month she receives a bill for $16,000. This purchases a monthly infusion of one chemotherapeutic agent.  Much of the bill is paid by her insurance, but her personal checking account will cough up about $1000 per month until she pays down her deductible. The invoice, however, is an illusion. The amount is not the actual number of dollars required to pay for services and materials rendered. Most of the money is diverted in accordance with contractual agreements between the hospital and ...
Source: The Health Care Blog - March 18, 2018 Category: Consumer Health News Authors: John Irvine Tags: Uncategorized Source Type: blogs

On the Non-Effectiveness of Cost Effectiveness Analyses
By ROBERT MCNUTT, MD & NORTIN HADLER, MD Take the example of a middle-aged woman undergoing chemotherapy for breast cancer. Month after month she receives a bill for $16,000. This purchases a monthly infusion of one chemotherapeutic agent.  Much of the bill is paid by her insurance, but her personal checking account will cough up about $1000 per month until she pays down her deductible. The invoice, however, is an illusion. The amount is not the actual number of dollars required to pay for services and materials rendered. Most of the money is diverted in accordance with contractual agreements between the hospital and ...
Source: The Health Care Blog - March 18, 2018 Category: Consumer Health News Authors: John Irvine Tags: Uncategorized Source Type: blogs

Automated identification of an aspirin-exacerbated respiratory disease cohort
An informatics search algorithm can successfully identify diagnosed and undiagnosed cases of aspirin-exacerbated respiratory disease (AERD) in the electronic health record.
Source: Journal of Allergy and Clinical Immunology - July 23, 2016 Category: Allergy & Immunology Authors: Katherine N. Cahill, Christina B. Johns, Jing Cui, Paige Wickner, David W. Bates, Tanya M. Laidlaw, Patrick E. Beeler Source Type: research