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Advances in the pharmacotherapeutic management of refractory peptic ulcers
Expert Opin Pharmacother. 2023 Apr 7. doi: 10.1080/14656566.2023.2199922. Online ahead of print.ABSTRACTINTRODUCTION: Refractory peptic ulcer is now a rare disease since most peptic ulcers heal with appropriate treatment with proton pump inhibitors (PPIs) and/or Helicobacter pylori eradication.AREAS COVERED: The most frequent cause of apparent refractoriness is lack of adherence to treatment. Persistence of H. pylori infection, use or abuse (often surreptitious) of high dose non-steroidal anti-inflammatory drugs (NSAIDs) or aspirin (ASA) are the two major causes of true refractory ulcers. There is a growing number of pepti...
Source: Expert Opinion on Pharmacotherapy - April 7, 2023 Category: Drugs & Pharmacology Authors: Cristina Borao Laguna Angel Lanas Source Type: research

In older patients receiving aspirin, < em > H pylori < /em > eradication reduced hospitalization or death due to peptic ulcer bleeding at 2.5 y
Ann Intern Med. 2023 Apr 4. doi: 10.7326/J23-0011. Online ahead of print.ABSTRACTHawkey C, Avery A, Coupland CAC, et al; HEAT trialists. Helicobacter pylori eradication for primary prevention of peptic ulcer bleeding in older patients prescribed aspirin in primary care (HEAT): a randomised, double-blind, placebo-controlled trial. Lancet. 2022;400:1597-1606. 36335970.PMID:37011389 | DOI:10.7326/J23-0011
Source: Annals of Internal Medicine - April 3, 2023 Category: Internal Medicine Authors: Abhilash Perisetti Prateek Sharma Source Type: research

A Review on Herbal Drugs Used in the Treatment of Peptic Ulcer
CONCLUSION: This study concluded several medicinal plants to effectively prevent or cure peptic ulcers caused by a variety of factors, including H. pylori, aspirin, indomethacin, alcohol, and others.PMID:36515023 | DOI:10.2174/1570163820666221212142221
Source: Current Drug Discovery Technologies - December 14, 2022 Category: Drugs & Pharmacology Authors: Anup Jyoti Roy Chinmoy Maut Hemanta Kumar Gogoi Syed Isfaqul Ahmed Ankita Kashyap Source Type: research

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