• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Highlights from the literature
Morphine and the baby brain Morphine gets used a lot in neonatal care, especially as we now understand the need to give appropriate analgesia and sedation to babies receiving intensive care. Yet there has always been a nagging concern that though we do the right thing in early life, we may be creating difficulties for these babies in later childhood. We should take some reassurance about this from a paper by Steinhorn (J Pediatr 2015;166:1200–7) in which 230 babies, all under 30 weeks at birth and a quarter of whom received morphine, were followed up at 2 and 7 years. At 2 years the morphine exposed babies demonstrat...
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - June 19, 2015 Category: Perinatology & Neonatology Tags: Clinical trials (epidemiology), Epidemiologic studies, Cerebral palsy, Epilepsy and seizures, Pain (neurology), Stroke, Child health, Neonatal and paediatric intensive care, Neonatal health, Pain (palliative care) Hyperion Source Type: research

Risk of type 2 diabetes mellitus in female breast cancer patients treated with morphine: a retrospective population-based time-dependent cohort study
A key element of the palliative care of cancer patients is the management of chronic pain [1]. Opioids continue to be a mainstay in the management of cancer pain in all treatment guidelines [2], and morphine is regarded as the “gold standard” [3–6]. Considered as broad-spectrum analgesics, opioids have multiple side effects and potential complications [7]. Our previous studies indicated that morphine treatment is associated with subdural hemorrhage [8], pulmonary embolism [9], and acute coronary syndrome [10] in cancer patients, as well as increased stroke incidence in prostate cancer patients [11].
Source: Diabetes Research and Clinical Practice - October 12, 2015 Category: Endocrinology Authors: Szu-Pang Yang, Chih-Hsin Muo, I-Kuan Wang, Yen-Jung Chang, Shih-Wei Lai, Cynthia Wei-Sheng Lee, Donald E. Morisky Source Type: research

Morphine exposure in preterm infants correlates with impaired cerebellar growth and poorer neurodevelopmental outcome
This study included 136 infants born at 24–32 weeks gestational age who underwent magnetic resonance imaging of the brain near birth and...
Source: Evidence-Based Medicine - November 22, 2016 Category: Internal Medicine Authors: McPherson, C. Tags: Clinical trials (epidemiology), Epidemiologic studies, Pain (neurology), Stroke, Pain (palliative care), Radiology, Drugs: musculoskeletal and joint diseases, Clinical diagnostic tests, Radiology (diagnostics) Aetiology/Harm Source Type: research