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Drug: Metformin
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Total 40 results found since Jan 2013.
Bidirectional association between diabetic peripheral neuropathy and vitamin B12 deficiency: Two longitudinal 9-year follow-up studies using a national sample cohort
CONCLUSION: DPN occurrence increased in diabetes with vit B12 deficiency and the incidence of vit B12 deficiency was also high in DPN patients. However, metformin showed opposite effects in both cohorts. Further studies clarifying the causal relationship among DPN occurrence, vit B12 deficiency, and metformin use are warranted.PMID:37344286 | DOI:10.1016/j.pcd.2023.06.006
Source: Primary Care - June 21, 2023 Category: Primary Care Authors: Heung Yong Jin Kyung Ae Lee Yu Ji Kim In Sun Gwak Tae Sun Park Sang Woo Yeom Jong Seung Kim Source Type: research
Metformin adherence and the risk of cardiovascular disease: a population-based cohort study
CONCLUSIONS: This study revealed that metformin adherence in patients with T2DM who required a first-line treatment may reduce the risk of subsequent CVD. Despite the availability of numerous novel antiglycemic agents, metformin adherence by patients who require a combination of antiglycemic agents provides an additional benefit of CVD protection.PMID:37051071 | PMC:PMC10084537 | DOI:10.1177/20406223231163115
Source: Adv Data - April 13, 2023 Category: Epidemiology Authors: Shun-Fan Yu Chien-Tai Hong Wan-Ting Chen Lung Chan Li-Nien Chien Source Type: research
Metformin use and associated risk of total joint replacement in patients with type 2 diabetes: a population-based matched cohort study
CMAJ. 2022 Dec 19;194(49):E1672-E1684. doi: 10.1503/cmaj.220952.ABSTRACTBACKGROUND: It is uncertain whether metformin use is associated with reduced risk of joint replacement in patients with type 2 diabetes mellitus. We aimed to establish whether metformin use was associated with a reduced risk of total knee replacement (TKR) or total hip replacement (THR) among these patients.METHODS: We selected patients with type 2 diabetes mellitus that was diagnosed between 2000 and 2012 from the Taiwan National Health Insurance Research Database. We used prescription time-distribution matching and propensity-score matching to balanc...
Source: cmaj - December 19, 2022 Category: General Medicine Authors: Zhaohua Zhu Jing-Yang Huang Guangfeng Ruan Peihua Cao Shibo Chen Yan Zhang Weiyu Han Tianyu Chen Xiaoyan Cai Jia Liu Yujin Tang Na Yu Qian Wang David J Hunter James Cheng-Chung Wei Changhai Ding Source Type: research
Association between first-step analgesic use and cancer in patients with diabetes
CONCLUSION: Regular use of analgesics by patients with diabetes decreased their risk of subsequent cancer development in this large national cohort. Compared with participants who did not develop cancer, those with cancer were older and more likely to be male, did not exercise, have more comorbidities (as assessed by CCI), and did not use analgesics regularly.PMID:36420887 | DOI:10.5414/CP204305
Source: Clinical Pharmacology and Therapeutics - November 24, 2022 Category: Drugs & Pharmacology Authors: Ie Byung Park Hwa Jeong Seo Source Type: research
