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Drug: Metronidazole
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Total 62 results found since Jan 2013.

Clinical benefits of systemic amoxicillin/metronidazole may depend on periodontitis stage and grade: An exploratory sub-analysis of the ABPARO trial
CONCLUSIONS: In generalized periodontitis stage III/grade C, a clinically relevant lower percentage of disease progression after adjunctive systemic amoxicillin/metronidazole was observed compared to placebo (PLAC: 9.7; 5.8/14.3% vs. ANTI: 4.7; 2.4/9.0%; p < .001).PMID:37293896 | DOI:10.1111/jcpe.13838
Source: Journal of Clinical Periodontology - June 9, 2023 Category: Dentistry Authors: Peter Eickholz Raphael Koch Moritz G öde Katrin Nickles Thomas Kocher Katrin Lorenz Ti-Sun Kim J örg Meyle Do ğan Kaner Ulrich Schlagenhauf Inga Harks Benjamin Ehmke Source Type: research

Efficacy of adjuvant metronidazole therapy on peri-implantitis: a systematic review and meta-analysis of randomized clinical studies
Peri-implant diseases are pathological conditions that affect the survival of dental implants. Etiological studies are limited, accepting a prevalence of 20% at the implant level and 24% at the patient level. The benefits of adjuvant metronidazole are controversial. A systematic review and meta-analysis of RCTs according to PRISMA and PICOS was performed with an electronic search over the last 10 years in MEDLINE (PubMed), WOS, Embase, and Cochrane Library. The risk of bias was measured using the Cochrane Risk of Bias tool and the methodological quality using the Jadad scale. Meta-analysis was performed with RevMan version...
Source: Frontiers in cellular and infection microbiology - May 23, 2023 Category: Microbiology Source Type: research

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Cochrane Database Syst Rev . 2022 Oct 4;10(10):CD009197. doi: 10.1002/14651858.CD009197.pub5 Abstract Background: There may be an association between periodontitis and cardiovascular disease (CVD); however, the evidence so far has been uncertain about whether periodontal therapy can help prevent CVD in people diagnosed with chronic periodontitis. This is the third update of a review originally published in 2014, and most recently updated in 2019. Although there is a new multidimensional staging and grading system for periodontitis, we have retained the label ' chronic periodontitis ' in this version of the review since ava...
Source: Dental Technology Blog - October 21, 2022 Category: Dentistry Source Type: news

Periodontal therapy for primary or secondary prevention of cardiovascular disease in people with periodontitis
CONCLUSIONS: For primary prevention of cardiovascular disease (CVD) in people diagnosed with periodontitis and metabolic syndrome, very low-certainty evidence was inconclusive about the effects of scaling and root planning plus antibiotics compared to supragingival scaling. There is no reliable evidence available regarding secondary prevention of CVD in people diagnosed with chronic periodontitis and CVD. Further trials are needed to reach conclusions about whether treatment for periodontal disease can help prevent occurrence or recurrence of CVD.PMID:36194420 | DOI:10.1002/14651858.CD009197.pub5
Source: Cochrane Database of Systematic Reviews - October 4, 2022 Category: General Medicine Authors: Zelin Ye Yubin Cao Cheng Miao Wei Liu Li Dong Zongkai Lv Zipporah Iheozor-Ejiofor Chunjie Li Source Type: research

Adjunctive benefits of systemic metronidazole on non-surgical treatment of peri-implantitis. A randomized placebo-controlled clinical trial
CONCLUSIONS: The use of systemic metronidazole as an adjunct to non-surgical treatment of peri-implantitis resulted in significant additional improvements in clinical, radiographic, and microbiological parameters after 12 months of follow-up. This study is registered in ClinicalTrials.gov (NCT03564301).PMID:34713471 | DOI:10.1111/jcpe.13564
Source: Journal of Clinical Periodontology - October 29, 2021 Category: Dentistry Authors: Carlota Blanco Alex Pico Jose Dopico Pilar G ándara Juan Blanco Antonio Li ñares Source Type: research

12-Year Follow-Up of Regenerative Endodontic Treatment of Immature Permanent Upper Incisors with Acute Abscess
Braz Dent J. 2020 Nov-Dec;31(6):680-684. doi: 10.1590/0103-6440202003663.ABSTRACTThis case report discusses the endodontic treatment of a 7-year-old girl who suffered trauma (intrusion) to the immature upper central incisors secondary to a fall from a bicycle. Thirty days after the accident the patient was brought by her mother for clinical and radiographic assessment with a chief complaint of swelling and tenderness to percussion and palpation. Acute apical abscess associated with immature teeth were diagnosed. A decision was made to perform regenerative endodontic treatment. Access cavities were made and the root canals ...
Source: Braz Dent J - November 25, 2020 Category: Dentistry Authors: Claudio Maniglia-Ferreira Eduardo Diogo Gurgel Filho Fabio de Almeida Gomes Sthefanny Amaral Reis Fernanda Geraldo Pappen Source Type: research