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Treatment Patterns, Clinical Outcomes, Health Care Resource Utilization and Costs in Older Patients With Metastatic Castration-Resistant Prostate Cancer in the United States: An Analysis of SEER-Medicare Data
This study aimed to generate real-world evidence on treatment patterns, clinical outcomes, health care resource utilization (HCRU), and costs among older patients with metastatic castration-resistant PC (mCRPC).MATERIALS AND METHODS: A claims algorithm based on treatments expected for mCRPC was used to identify men ≥65 years old with mCRPC in the SEER-Medicare data between 2007 and 2019. The index date was defined as the date of the start of first-line therapy (1L). Treatment patterns and all-cause and PC-specific HCRU and costs were measured in the 12 months preindex period and the postindex follow-up period. Time to ne...
Source: Clinical Prostate Cancer - May 29, 2023 Category: Cancer & Oncology Authors: Umang Swami Himani Aggarwal Mo Zhou Shan Jiang Jeri Kim Weiyan Li Fran çois Laliberté Bruno Emond Neeraj Agarwal Source Type: research

Sequential intravesical gemcitabine-docetaxel vs. bacillus Calmette-Guerin (BCG) in the treatment of non-muscle invasive bladder cancer: A preliminary cost-effectiveness analysis
CONCLUSIONS: The findings of this preliminary cost-effectiveness analysis are novel in that they highlight a well tolerated, efficacious drug that is less expensive than the traditional gold standard therapy. In modern medicine, we are more often challenged by agents with marginally increased efficacy but at significantly higher costs; gemcitabine-docetaxel represents a rare entity which is a success for both patients and healthcare systems alike.PMID:37127478 | DOI:10.1016/j.urolonc.2023.04.005
Source: Urologic Oncology - May 1, 2023 Category: Urology & Nephrology Authors: Laura Bukavina Spencer Bell Vignesh T Packiam Marc Smaldone Philip Abbosh Robert Uzzo Alexander Kutikov Andres F Correa Diana E Magee Source Type: research

Treatment Intensification Patterns and Utilization in Patients with Metastatic Castration-Sensitive Prostate Cancer
CONCLUSION: Both medical oncology and urology providers need to improve their treatment intensification efforts for men with mCSPC to increase their patients' overall survival.PMID:35864053 | DOI:10.1016/j.clgc.2022.06.017
Source: Clinical Prostate Cancer - July 21, 2022 Category: Cancer & Oncology Authors: Elisabeth I Heath Gregory E Dyson Frank C Cackowski Jason Hafron Isaac Powell Source Type: research