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TWiV 1002: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses completeness and spin of medRxiv preprints and associated published abstracts of COVID-19 randomized clinical trials, lessons learned from a COVID-19 dog screening pilot in California K-12 schools, SARS-CoV-2 reinfection and severity of the disease, effectiveness of COVID-19 bivalent vaccine, Molnupiravir and risk of post-acute sequelae of COVID-19, risk of new-onset long Covid following reinfection with SARS-CoV-2, low vitamin D levels associated with long COVID syndrome in COVID-19 survivors, and clinical experience with the α2A-adrenoceptor agonist, guanfacine, an...
Source: This Week in Virology - MP3 Edition - April 29, 2023 Category: Virology Authors: VIncent Racaniello Source Type: podcasts

N-acetylcysteine in substance use disorder: a lesson from preclinical and clinical research
Pharmacol Rep. 2021 Jun 6. doi: 10.1007/s43440-021-00283-7. Online ahead of print.ABSTRACTSubstance use disorder (SUD) is a chronic brain condition, with compulsive and uncontrollable drug-seeking that leads to long-lasting and harmful consequences. The factors contributing to the development of SUD, as well as its treatment settings, are not fully understood. Alterations in brain glutamate homeostasis in humans and animals implicate a key role of this neurotransmitter in SUD, while the modulation of glutamate transporters has been pointed as a new strategy to diminish the excitatory glutamatergic transmission observed aft...
Source: Pharmacological Reports - June 6, 2021 Category: Drugs & Pharmacology Authors: Irena Smaga Ma łgorzata Frankowska Ma łgorzata Filip Source Type: research

LITFL Review 311
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog Welcome to the 311th LITFL Review! Your regular and reliable source for the highest highlights, sneakiest sneak peeks and loudest shout-outs from the webbed world of emergency medicine and critical care. Each week the LITFL team casts the spotlight on the blogosphere’s best and brightest and deliver a bite-sized chunk of FOAM. The Most Fair Dinkum Ripper Beauts of the Week Do you have an ED spa at your shop? Invest in yourself and see the results as you flourish. O...
Source: Life in the Fast Lane - December 18, 2017 Category: Emergency Medicine Authors: Marjorie Lazoff, MD Tags: LITFL review LITFL R/V Source Type: blogs