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Polyoxometalate nanoclusters act as broad-spectrum antioxidants to alleviate ischemic stroke by intrathecal injection
Conclusion: Intrathecal injection significantly improved the delivery and efficacy of POM nanoclusters to the brain, resulting in the rapid accumulation of POM nanoclusters in the ischemic penumbra. Due to this, we confirmed that the POM nanoclusters could be used as nano-antioxidants to inhibit oxidative stress as well as inflammatory damage effectively.
Source: Journal of Nuclear Medicine - May 14, 2020 Category: Nuclear Medicine Authors: Rosenkrans, Z., Li, S., Jiang, D., NI, D., Engle, J., Cai, W. Tags: Center for Molecular Imaging Innovation & amp; Translation (CMIIT) YIA Symposium Source Type: research

Preliminary study about the relationship between degree of internal carotid artery stenosis, wall shear stress on MR angiography and 18F-FDG uptake on PET/CT
Conclusions: These preliminary results indicated that there were significant correlations between degree of internal carotid artery stenosis, WSS and 18F-FDG uptake in patients with carotid artery stenosis. Furthermore, the relationship between WSS and 18F-FDG uptake was higher than that between degree of internal carotid artery stenosis and 18F-FDG uptake.
Source: Journal of Nuclear Medicine - May 14, 2020 Category: Nuclear Medicine Authors: Takami, Y., Norikane, T., Yamamoto, Y., Fujimoto, K., Mitamura, K., Nishiyama, Y. Tags: Clinical Science (Poster Session) Source Type: research

Nutrition, risk factors, prevention, and imaging: The 2018 Mario Verani Lecture
AbstractHeart disease has been the leading cause of death in the United States since 1918. Cardiac mortality rates have dramatically decreased in this era of advanced medical and interventional therapies. However, this has been aptly described as “mopping up the floor instead of turning off the faucet.” With this recognition, prevention in cardiology is poised to become a central focus. Within prevention, dietary intervention is recognized as the single largest opportunity for improved cardiovascular outcomes, including improvement or el imination of cardiac risk factors, prevention of myocardial infarction, stroke and...
Source: Journal of Nuclear Cardiology - November 5, 2018 Category: Nuclear Medicine Source Type: research

Alzheimers Disease: A Review of Recent Developments and the Role of Imaging
1114Purpose: Alzheimer’s disease (AD), the most common form of dementia, is a devastating illness that will affect an estimated 5.7 million Americans and almost 50 million people worldwide in 2018, with numbers expected to nearly triple by 2050. While mortality related to heart disease and stroke has continued to decline, the rate of AD-related death in the United States more than doubled in the period from 2000-2015. Now the 6th leading cause of death, it is the least preventable and treatable of the major causes, and places a tremendous financial, physical, and emotional burden on the estimated 16 million unpaid ca...
Source: Journal of Nuclear Medicine - May 20, 2019 Category: Nuclear Medicine Authors: Ismail, H., Wang, L. Tags: Educational Exhibit Posters Source Type: research