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Drug: Fentanyl
Countries: USA Health
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Total 192 results found since Jan 2013.
Detection of fentanyl, synthetic opioids, and ketamine in hair specimens from purposive samples of American and Italian populations
J Forensic Sci. 2023 Jul 28. doi: 10.1111/1556-4029.15348. Online ahead of print.ABSTRACTWith the current crisis related to the diffusion of fentanyl and other novel opioids in several countries and populations, new and effective approaches are needed to better elucidate the phenomenon. In this context, hair testing offers a unique perspective in the investigation of drug consumption, producing useful information in terms of exposure to psychoactive substances. In this research, we applied targeted ultra-high performance liquid chromatography tandem mass spectrometry (UHPLC-MS/MS) analytical methods to detect novel synthet...
Source: Journal of Forensic Sciences - July 29, 2023 Category: Forensic Medicine Authors: Alberto Salomone Martina Galletto Marta Massano Daniele Di Corcia Joseph J Palamar Marco Vincenti Source Type: research
Pressure sensitive adhesives and paper spray-mass spectrometry for the collection and analysis of fentanyl-related compounds from shipping materials
J Forensic Sci. 2023 Jul 26. doi: 10.1111/1556-4029.15320. Online ahead of print.ABSTRACTThe rise of fentanyl and fentanyl analogs in the drug supply pose serious threats to public health. Much of these compounds enter the United States through shipping routes. Here we provide a method for fentanyl screening and analysis that utilizes pressure-sensitive adhesive (PSA) lined paper to recover drug residues from parcel-related surfaces. The paper used is commercially available repositionable notes (also called post-it or sticky notes). From this paper, mass spectra were obtained by paper spray-mass spectrometry (PS-MS), where...
Source: Journal of Forensic Sciences - July 26, 2023 Category: Forensic Medicine Authors: Sarah Prunty Daniel Carmany Elizabeth S Dhummakupt Nicholas E Manicke Source Type: research
Evaluating the sensitivity, stability, and cross-reactivity of commercial fentanyl immunoassay test strips
This study presents an evaluation of four commercial FTS: Rapid Response from BTNX, Inc.; T-Dip Fentanyl (FTY) Urine Dip Cards obtained from Amazon.com; Premier BioDip FYL10 from Premier Biotech Inc.; and MobileDetect Fentanyl strips from DetectaChem, Inc. Performance characteristics curves were used to compare the products' sensitivity, showing that all can reliably detect fentanyl in aqueous solutions at concentrations below 1 μg/mL, with some of the tests able to reliably detect the drug at 200 ng/mL. A stability study demonstrates the performance of all four FTS brands was only slightly affected after 30 days of stora...
Source: Journal of Forensic Sciences - July 7, 2023 Category: Forensic Medicine Authors: Sandra E Rodriguez-Cruz Source Type: research
Illicitly Manufactured Fentanyl-Involved Overdose Deaths with Detected Xylazine - United States, January 2019-June 2022
This report uses data from CDC's State Unintentional Drug Overdose Reporting System (SUDORS) to describe IMF-involved§ overdose deaths with and without xylazine detected that occurred during January 2019-June 2022. Among 21 jurisdictions, which included 20 states and the District of Columbia, the monthly percentage of IMF-involved deaths with xylazine detected increased 276%, from 2.9% to 10.9%. Among IMF-involved deaths during January 2021-June 2022 in 32 jurisdictions, xylazine was detected in a higher percentage of jurisdictions in the Northeast U.S. Census Bureau region; listing detected xylazine as a cause of death v...
Source: MMWR Morb Mortal Wkl... - June 29, 2023 Category: Epidemiology Authors: Mbabazi Kariisa Julie O'Donnell Sagar Kumar Christine L Mattson Bruce A Goldberger Source Type: research
An interlaboratory study to evaluate the utility of gas chromatography-mass spectrometry and gas chromatography-infrared spectroscopy spectral libraries in the forensic analysis of fentanyl-related substances
This study describes the utility of a previously reported gas chromatography-infrared (GC-IR) library for the identification of FRS within a blind, interlaboratory study (ILS) involving seven forensic laboratories. Twenty FRS reference materials, including those with isomer pairs in the library, were selected based on either their presence in the NIST library and/or some similarity of the mass spectra information produced. The ILS participants were requested to use the Florida International University (FIU) GC-MS and GC-IR libraries supplied by FIU to search for matches to their unknown spectra generated from in-house GC-M...
Source: Journal of Forensic Sciences - June 13, 2023 Category: Forensic Medicine Authors: Kimiko Ferguson Jeannette Perr Sherri Tupik Michael Gilbert Reta Newman Agnes Winokur Ivette Vallejo Stephen Hokanson Matthew Pothier Brook Knapp Misty Icard Kevin Kramer Jose Almirall Source Type: research
The effects of the (fentanyl-fueled) drug overdose epidemic on medicolegal death investigation in the United States
J Forensic Sci. 2023 Jun 12. doi: 10.1111/1556-4029.15304. Online ahead of print.ABSTRACTThe evolving opioid epidemic in the United States, fueled by illicit fentanyl, has greatly increased deaths from illicit drug use. These nonnatural deaths require formal death investigation. The National Association of Medical Examiners states in its Forensic Autopsy Performance Standards that autopsy remains a necessary component for proper investigation of suspected acute overdose deaths. If a death investigation office lacks adequate resources to investigate all deaths under its jurisdiction while meeting expected standards, then th...
Source: Journal of Forensic Sciences - June 12, 2023 Category: Forensic Medicine Authors: Gregory G Davis Corinne L Fligner Source Type: research
