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Johnson & Johnson Expands Phase 2a Clinical Trial of COVID-19 Vaccine Candidate to Include Adolescents
New Brunswick, NJ (April 2, 2021) – Johnson & Johnson (the Company) has begun vaccinating adolescent participants in the ongoing Phase 2a clinical trial for its COVID-19 vaccine candidate, developed by the Janssen Pharmaceutical Companies of Johnson & Johnson. “The COVID-19 pandemic has had a profound impact on adolescents, not just with the complications of the disease, but with their education, mental health, and wellbeing,” said Paul Stoffels, M.D., Vice Chairman of the Executive Committee and Chief Scientific Officer at Johnson & Johnson. “It is vital that we develop vaccines for everyone, everywher...
Source: Johnson and Johnson - April 2, 2021 Category: Pharmaceuticals Tags: Our Company Source Type: news

Fight Aging! Newsletter, August 24th 2020
We report that electrical stimulation (ES) stimulation of post-stroke aged rats led to an improved functional recovery of spatial long-term memory (T-maze), but not on the rotating pole or the inclined plane, both tests requiring complex sensorimotor skills. Surprisingly, ES had a detrimental effect on the asymmetric sensorimotor deficit. Histologically, there was a robust increase in the number of doublecortin-positive cells in the dentate gyrus and SVZ of the infarcted hemisphere and the presence of a considerable number of neurons expressing tubulin beta III in the infarcted area. Among the genes that were unique...
Source: Fight Aging! - August 23, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, May 25th 2020
In conclusion, our results suggest a previously unknown mechanism whereby the canonical NF-κB cascade and a mitochondrial fission pathway interdependently regulate endothelial inflammation. Lin28 as a Target for Nerve Regeneration https://www.fightaging.org/archives/2020/05/lin28-as-a-target-for-nerve-regeneration/ Researchers here show that the gene Lin28 regulates axon regrowth. In mice, raised levels of Lin28 produce greater regeneration of nerve injuries. Past research has investigated Lin28 from the standpoint of producing a more general improvement in regenerative capacity. It improves mitochondri...
Source: Fight Aging! - May 24, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

What is the Recurrence Rate for Guillian-Barr é Syndrome and Should She Get An Influenza Vaccine?
Discussion Guillian-Barré syndrome (GBS) is an acquired, acute, inflammatory, demyelinating polyneuropathy. It is the most common cause of acute and subacute flaccid paralysis in children. GBS causes about 0.4-1.3 cases per 100,000 persons/year in children. It can occur in any age group and the incidence increases among all age groups until a peak in the 50s. Both genders are affected and there may be a slight increase in males. GBS usually occurs 2-4 weeks after a prodromal gastroenteritis or respiratory illness. GBS causes autoantibody production against Schwann cells of the neuron and the axon itself. There is ...
Source: PediatricEducation.org - November 19, 2018 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Funtabulously Frivolous Friday Five 233
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog Just when you thought your brain could unwind on a Friday, you realise that it would rather be challenged with some good old fashioned medical trivia FFFF…introducing Funtabulously Frivolous Friday Five 233. Readers can subscribe to FFFF RSS or subscribe to the FFFF weekly EMAIL Question 1: Who popularised museli? + Reveal the Funtabulous Answer expand(document.getElementById('ddet201504324'));expand(document.getElementById('ddetlink201504324')) Dr Maximilian Birc...
Source: Life in the Fast Lane - April 6, 2018 Category: Emergency Medicine Authors: Neil Long Tags: Frivolous Friday Five Bircher Bircher Museli Clare Stanton Ekbom syndrome II Ernest W Goodpasture Essex Lopresti Goodpastures disease hugo flecker irukandji irukandji syndrome jack barnes John Range Maximilian Bircher-Benner Pa Source Type: blogs

How the MMR Vaccine Caused My Son ’ s Encephalopathy, A.K.A. Autism
In 2016 I found myself waiting at a Colorado doctor’s office with my 12-year-old son, hoping to qualify for a cannabis prescription for him. I had traveled a long way from mainstream medicine in ten years. As a West Point graduate, Army Medical Service Corps Junior Officer of the Year and Medical Intelligence Officer for NATO Peacekeeping Forces, none of those experiences adequately prepared me for the greatest medical challenge and controversy of our time. My toddler son had suffered a vaccine induced brain injury from the MMR vaccine in 2005. The Harvard trained physician I was meeting with had been practicing medicine...
Source: vactruth.com - November 18, 2017 Category: Allergy & Immunology Authors: Pam Long Tags: Human Pam Long Top Stories Arthur Krigsman autism encephalopathy inflammatory bowel disease P.A.N.D.A.S. Source Type: blogs