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Drug: Medroxyprogesterone
Countries: South Africa Health

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Total 4 results found since Jan 2013.

Prevalence and Incidence of Sexually Transmitted Infection in Injectable Progestin Contraception Users in South Africa
DISCUSSION: Among South African participants enrolled in VOICE, DMPA-IM and NETEN users differed in prevalence of HSV-2 at baseline but did not differ in the incidence of chlamydia, gonorrhea, trichomoniasis, syphilis, or HSV-2 infection. Differential HIV-1 acquisition, previously demonstrated in this cohort, does not appear to be explained by differential STI acquisition. However, the high incidence of multiple STIs reinforces the need to accelerate access to comprehensive sexual and reproductive health services.PMID:35669097 | PMC:PMC9165437 | DOI:10.3389/frph.2021.668685
Source: Herpes - June 7, 2022 Category: Infectious Diseases Authors: Lisa M Noguchi Jeanne M Marrazzo Barbara Richardson Sharon L Hillier Jennifer E Balkus Thesla Palanee-Phillips Gonasagrie Nair Ravindre Panchia Jeanna Piper Kailazarid Gomez Gita Ramjee Z Mike Chirenje Source Type: research

Incidence of herpes simplex virus type 2 infection among African women using depot medroxyprogesterone acetate, a copper intrauterine device, or a levonorgestrel implant for contraception: a nested randomized trial
Clin Infect Dis. 2021 Dec 15:ciab1027. doi: 10.1093/cid/ciab1027. Online ahead of print.ABSTRACTBACKGROUND: Globally, women have higher herpes simplex type 2 (HSV-2) prevalence than men; data from observational studies suggest a possible association of HSV-2 acquisition with use of intramuscular depot medroxyprogesterone acetate (DMPA-IM).METHODS: Within a randomized trial of the effect of three contraceptive methods - DMPA-IM, a copper intrauterine device (IUD), and a levonorgestrel (LNG) implant - on HIV acquisition, we assessed HSV-2 acquisition. HSV-2 and HIV seronegative women, aged 16-35 years, and seeking effective ...
Source: Herpes - December 15, 2021 Category: Infectious Diseases Authors: Nelly R Mugo Randy M Stalter Renee Heffron Helen Rees Caitlin W Scoville Charles Morrison Athena P Kourtis Elizabeth Bukusi Mags Beksinka Neena M Philip Ivana Beesham Jen Deese Vinodh Edward Deborah Donnell Jared M Baeten Evidence for Contraceptive Option Source Type: research

Hormone replacement therapy after surgery for epithelial ovarian cancer.
CONCLUSIONS: Hormone replacement therapy may slightly improve overall survival in women who have undergone surgical treatment for EOC, but the certainty of the evidence is low. HRT may make little or no difference to quality of life, incidence of breast cancer, TIA, CVA and MI as the certainty of the evidence has been assessed as very low. There may be little or no effect of HRT use on progression-free survival. The evidence in this review is limited by imprecision and incompleteness of reported relevant outcomes and therefore the results should be interpreted with caution. Future well-designed RCTs are required as this is...
Source: Cochrane Database of Systematic Reviews - January 27, 2020 Category: General Medicine Authors: Saeaib N, Peeyananjarassri K, Liabsuetrakul T, Buhachat R, Myriokefalitaki E Tags: Cochrane Database Syst Rev Source Type: research