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Trends in mortality, cardiovascular complications, and risk factors in type 2 diabetes.
CONCLUSION: Despite highly organised diabetes care, excess incident cardiovascular events and mortality due to T2DM did not decrease over the study period. Life expectancy of T2DM patients is significantly reduced and risk factor control is suboptimal. This suggests there is considerable room for improvement of diabetes care in the Netherlands. PMID: 31814586 [PubMed - in process]
Source: The Netherlands Journal of Medicine - November 30, 2019 Category: General Medicine Authors: Heintjes EM, Houben E, Beekman-Hendriks WL, Lighaam E, Cremers SM, Penning-van Beest FJA, Stehouwer CDA, Herings RMC Tags: Neth J Med Source Type: research

Radial versus femoral access and bivalirudin versus unfractionated heparin in invasively managed patients with acute coronary syndrome (MATRIX): final 1-year results of a multicentre, randomised controlled trial
Publication date: Available online 25 August 2018Source: The LancetAuthor(s): Marco Valgimigli, Enrico Frigoli, Sergio Leonardi, Pascal Vranckx, Martina Rothenbühler, Matteo Tebaldi, Ferdinando Varbella, Paolo Calabrò, Stefano Garducci, Paolo Rubartelli, Carlo Briguori, Giuseppe Andó, Maurizio Ferrario, Ugo Limbruno, Roberto Garbo, Paolo Sganzerla, Filippo Russo, Marco Nazzaro, Alessandro Lupi, Bernardo CorteseSummaryBackgroundThe Minimizing Adverse Haemorrhagic Events by Transradial Access Site and Systemic Implementation of Angiox (MATRIX) programme was designed to assess the comparative safety and effectiveness of ra...
Source: The Lancet - August 25, 2018 Category: General Medicine Source Type: research

Of Cardiac Holes and Crew Leaders
I enjoyed reading, and learned a lot from, Drs. Dalen and Alpert's article1 on closure of a foramen ovale to prevent cryptogenic stroke. It is a timely review that organizes evidence that, until now, had been somewhat confusing. In the article, the word foramen (from the Latin forare, meaning to pierce or bore a hole) was meant to appear 61 times. Unfortunately, it was mistakenly replaced by the word foremen (from the Dutch voormen, meaning the leaders of work crews, usually men, or the spokesmen for juries) on 27 of the 61 occasions.
Source: The American Journal of Medicine - October 1, 2018 Category: General Medicine Authors: Fernando Elijovich Tags: Letter Source Type: research

Diagnostic and (new) therapeutic options for resistant hypertension: a short review.
Abstract Hypertension is a major risk factor for ischaemic heart disease and stroke. Despite the availability of numerous pharmacological treatment options, blood pressure (BP) targets are often not achieved. The inability to reach BP levels below 140/90 mmHg despite the use of three or more antihypertensive drugs is defined as resistant hypertension (RH). The etiology for RH is multifactorial. First, BP should be appropriately measured. In order to improve BP control, lifestyle modification should be recommended, adherence should be carefully assessed to exclude pseudo-resistance, and efforts should be made to ex...
Source: The Netherlands Journal of Medicine - November 30, 2019 Category: General Medicine Authors: Feyz L, Peeters L, Daemen J, Versmissen J Tags: Neth J Med Source Type: research

Correction to: Differences in factors influencing the use of eRehabilitation after stroke; a cross-sectional comparison between Brazilian and Dutch healthcare professionals
An amendment to this paper has been published and can be accessed via the original article.
Source: BMC Health Services Research - July 1, 2020 Category: General Medicine Authors: Berber Brouns, Leti van Bodegom-Vos, Arend J. de Kloet, Thea P. M. Vliet Vlieland, Ingrid L. C. Gil, L ígia M. N. Souza, Lucia W. Braga and Jorit J. L. Meesters Tags: Correction Source Type: research

Validating risk models versus age alone for atrial fibrillation in a young Dutch population cohort: should atrial fibrillation risk prediction be expanded to younger community members?
Conclusion Multivariable models accurately discriminate for 5-year and 10-year AF risk among young European community-dwelling individuals. However, their additional discriminatory value over age alone was limited. Selection strategies for primary AF screening using multivariable models should not be expanded to younger individuals.
Source: BMJ Open - February 16, 2022 Category: General Medicine Authors: Himmelreich, J. C. L., Harskamp, R. E., Geelhoed, B., Virdone, S., Lucassen, W. A. M., Gansevoort, R. T., Rienstra, M. Tags: Open access, Cardiovascular medicine Source Type: research

Cohort profile: the Utrecht Cardiovascular Cohort-Second Manifestations of Arterial Disease (UCC-SMART) Study-an ongoing prospective cohort study of patients at high cardiovascular risk in the Netherlands
This article provides an update of the rationale, design, included patients, measurements and findings from the start in 1996 to date. Participants The UCC-SMART Study includes patients aged 18–90 years referred to the University Medical Center Utrecht, the Netherlands, for management of cardiovascular disease (CVD) or severe cardiovascular risk factors. Since September 1996, a total of 14 830 patients have been included. Upon inclusion, patients undergo a standardised screening programme, including questionnaires, vital signs, laboratory measurements, an ECG, vascular ultrasound of carotid arteries and aorta, ankle...
Source: BMJ Open - February 20, 2023 Category: General Medicine Authors: Castelijns, M. C., Helmink, M. A. G., Hageman, S. H. J., Asselbergs, F. W., de Borst, G. J., Bots, M. L., Cramer, M. J., Dorresteijn, J. A. N., Emmelot-Vonk, M. H., Geerlings, M. I., de Jong, P. A., van der Kaaij, N. P., Kappelle, L. J., Lely, A. T., van Tags: Open access, Cardiovascular medicine Source Type: research

Screening over 100 000 patients in 39 general practices in the Netherlands for anticoagulation underprescription in atrial fibrillation: a descriptive, cross-sectional study
Conclusions In this large Dutch study among GPs, we observed 9.8% underprescription of OAC in AF patients. In 76% of the AF patients lacking a prescription for OAC, no documentation for deviating from the guidelines was found. Only in a minority of cases detection of OAC underprescription lead to OAC initiation.
Source: BMJ Open - August 18, 2023 Category: General Medicine Authors: Voorhout, L., Pisters, R., Geurts, C. H. P. H., Oostindjer, A., van Doorn, S., Rila, H., Fuijkschot, W. W., Verheugt, F., Hemels, M. E. W. Tags: Open access, Cardiovascular medicine Source Type: research

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