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Immunogenicity and safety of routine 13-valent pneumococcal conjugate vaccination outside recommended age range in patients with hematological malignancies and solid tumors
Vaccine. 2022 Feb 3:S0264-410X(22)00102-5. doi: 10.1016/j.vaccine.2022.01.056. Online ahead of print.ABSTRACTHematological malignancy and solid tumor are major risks for invasive pneumococcal disease. Thirteen-valent pneumococcal conjugate vaccine (PCV13) is recommended for immunocompromised patients aged 6 years and older and adults who had not received the vaccine previously. However, vaccination for these individuals is not publicly subsidized in Japan. We measured pneumococcal serotype-specific IgGs (Pn-IgGs) and opsonophagocytic activities (Pn-OPAs) against PCV13 serotypes (1, 3, 5, 6A, 7F, and 19A) in patients with h...
Source: Vaccine - February 7, 2022 Category: Allergy & Immunology Authors: Kenichi Takeshita Naruhiko Ishiwada Noriko Takeuchi Misako Ohkusu Mihoko Ohata Moeko Hino Haruka Hishiki Yusuke Takeda Emiko Sakaida Yoshiko Takahashi Naoki Shimojo Hiromichi Hamada Source Type: research

Covax, the Developing World ’ s Hope against COVID, Has Made It Only Halfway
Delivery of syringes for the vaccination campaign in El Salvador. Latin American countries have made steady progress in immunizing their populations, partly through direct negotiations between their governments and suppliers and partly through international cooperation. CREDIT: PAHO By Humberto MárquezCARACAS, Jan 20 2022 (IPS) The Covax initiative, the hope of the countries of the developing South to immunize their populations against COVID-19, only met half of its goals in 2021. And as 2022 begins, and the omicron variant of the virus is spreading fast, the scheme still depends on the decisions of pharmaceutical compani...
Source: IPS Inter Press Service - Health - January 20, 2022 Category: International Medicine & Public Health Authors: Humberto Marquez Tags: COVID-19 Development & Aid Editors' Choice Featured Global Global Governance Headlines Health Humanitarian Emergencies Regional Categories TerraViva United Nations COVAX COVID-19 vaccines Source Type: news

Etiological and epidemiological features of acute meningitis or encephalitis in China: a nationwide active surveillance study
Lancet Reg Health West Pac. 2022 Jan 3;20:100361. doi: 10.1016/j.lanwpc.2021.100361. eCollection 2022 Mar.ABSTRACTBACKGROUND: Acute meningitis or encephalitis (AME) results from a neurological infection causing high case fatality and severe sequelae. AME lacked comprehensive surveillance in China.METHODS: Nation-wide surveillance of all-age patients with AME syndromes was conducted in 144 sentinel hospitals of 29 provinces in China. Eleven AME-causative viral and bacterial pathogens were tested with multiple diagnostic methods.FINDINGS: Between 2009 and 2018, 20,454 AME patients were recruited for tests. Based on 9,079 pat...
Source: Herpes - January 17, 2022 Category: Infectious Diseases Authors: Li-Ping Wang Yang Yuan Ying-Le Liu Qing-Bin Lu Lu-Sha Shi Xiang Ren Shi-Xia Zhou Hai-Yang Zhang Xiao-Ai Zhang Xin Wang Yi-Fei Wang Sheng-Hong Lin Cui-Hong Zhang Meng-Jie Geng Jun Li Shi-Wen Zhao Zhi-Gang Yi Xiao Chen Zuo-Sen Yang Lei Meng Xin-Hua Wang Ai- Source Type: research

Roche COVID-19 At-Home Test granted FDA Emergency Use Authorization to expand access to rapid self-testing solutions in the United States
Rapid test to support the American public ’s fight against the COVID-19 pandemic, with availability to purchase over-the-counter (OTC) at pharmacies and retailers nationwideThe COVID-19 At-Home Test uses a simple nasal swab sample to enable individuals to self-test at home and receive accurate, reliable and quick results in as few as 20 minutes for SARS-CoV-2 and all known variants of concern, including Omicron.EUA granted through Roche ’s participation in the National Institutes of Health (NIH) Rapid Acceleration of Diagnostics (RADx) Independent Test Assessment Program to bring rapid tests to the OTC marketBasel, 24 ...
Source: Roche Media News - December 24, 2021 Category: Pharmaceuticals Source Type: news

Whole-genome analysis-based phylogeographic investigation of < em > Streptococcus pneumoniae < /em > serotype 19A sequence type 320 isolates in Japan
Antimicrob Agents Chemother. 2021 Dec 20:AAC0139521. doi: 10.1128/AAC.01395-21. Online ahead of print.ABSTRACTAfter the introduction of the seven-valent pneumococcal conjugate vaccine, the global spread of multidrug resistant serotype 19A-ST320 strains became a public health concern. In Japan, the main genotype of serotype 19A was ST3111, and the identification rate of ST320 was low. Although the isolates were sporadically detected in both adults and children, their origin remains unknown. Thus, by combining pneumococcal isolates collected in three nationwide pneumococcal surveillance studies conducted in Japan between 200...
Source: Antimicrobial Agents and Chemotherapy - December 21, 2021 Category: Microbiology Authors: Satoshi Nakano Takao Fujisawa Bin Chang Yutaka Ito Hideki Akeda Jiro Fujita Yasufumi Matsumura Masaki Yamamoto Shigeru Suga Kazunori Oishi Miki Nagao Makoto Ohnishi Source Type: research

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