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Drug: Fortamet
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Total 53 results found since Jan 2013.

Metformin exerts synergistic anti-proliferative effects with liraglutide in human umbilical vein endothelial cells (HUVECs)
CONCLUSION: This study showed that combination therapy with Lira and Met could effectively reduce cell proliferation, induce apoptosis, and inhibit cell migration in the HUVECs. This study provides evidence to support using Met in combination with Lira as a treatment option for patients with type-2 diabetes and cancer.PMID:35656067 | PMC:PMC9150808 | DOI:10.22038/IJBMS.2022.64117.14117
Source: Cancer Control - June 3, 2022 Category: Cancer & Oncology Authors: Amir Shadboorestan Samane Eftekhari Negar Mottaghi-Dastjerdi Rezvan Shahparvari Parastoo Tarighi Hoda Jahandar Homa Faghihi Hamed Montazeri Source Type: research

The The use of oral glucose-lowering agents (GLAs) in β-thalassemia patients with diabetes: Preliminary data from a retrospective study of ICET-A Network
CONCLUSION: This retrospective study covers an unexplored area of research in patients with thalassemia and GD. Oral GLAs appear to be safe and effective for the treatment of diabetes mellitus in patients with thalassemia, and can achieve adequate glycemic control for a substantial period of time.PMID:35546014 | DOI:10.23750/abm.v93i2.12056
Source: Acta Bio-Medica : Atenei Parmensis - May 12, 2022 Category: General Medicine Authors: Vincenzo De Sanctis Ashraf Soliman Ploutarchos Tzoulis Shahina Daar Antonis Kattamis Polyxeni Delaporta Mehran Karimi Mohamed A Yassin Tahereh Zarei Forough Saki Katia Sapunarova Atanas Banchev Maria Concetta Galati Giuseppe Raiola Giuseppe Messina Saveri Source Type: research

Modulatory Effects of Metformin Alone and in Combination with Cimetidine and Ibuprofen on T Cell-related Parameters in a Breast Cancer Model
Iran J Allergy Asthma Immunol. 2021 Sep 28;20(5):600-613. doi: 10.18502/ijaai.v20i5.7410.ABSTRACTMetformin, cimetidine, and ibuprofen separately exhibit immunomodulatory and anti-tumorigenic effects. Herein, the impacts of metformin alone and in combination with cimetidine/ibuprofen on some Th1- and regulatory T (Treg) cell-related parameters were evaluated using a breast cancer (BC) model. For establishing the BC model, four groups of Balb/c mice were challenged with the carcinoma cell line. After 11-30 days post-induction, they were treated intraperitoneally (with metformin (200 mg/kg), "metformin plus cimetidine (20 mg/...
Source: Iranian Journal of Allergy, Asthma and Immunology - October 19, 2021 Category: Allergy & Immunology Authors: Fereshteh Taghipour Omolbanin Oladpour Mohammad Taghi Rezayati Hossain Khorramdelazad Maryam Nemati Zahra Taghipour Javad Masoumi Zuhair Mohammad Hassan Abdollah Jafarzadeh Source Type: research