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Specialty: Molecular Biology
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Total 331 results found since Jan 2013.

Pyramiding resistance genes for bacterial leaf blight (Xanthomonas oryzae pv. Oryzae) into the popular rice variety, Pratikshya through marker assisted backcrossing
CONCLUSION: The three-gene pyramided lines showed a high level of resistance to BLB infection and are anticipated to offer a significant yield advantage over the recipient parent Pratikshya. The pyramided lines can further be used for multi-location trial, so as to be released as a variety or can be used as a potential donor for BLB resistance genes.PMID:37725285 | DOI:10.1007/s11033-023-08805-7
Source: Molecular Biology Reports - September 19, 2023 Category: Molecular Biology Authors: Madhuri Pradhan Debendranath Bastia Kailash Chandra Samal Manasi Dash Jyoti Prakash Sahoo Source Type: research

Genomic profile of diabetic retinopathy in a north indian cohort
CONCLUSION: Our study provides strong evidence of association between the TCF7L2 variants and DR susceptibility.PMID:37700140 | DOI:10.1007/s11033-023-08772-z
Source: Molecular Biology Reports - September 12, 2023 Category: Molecular Biology Authors: Ruhi Sikka Priyanka Raina Rhibhu Soni Himanshu Gupta A J S Bhanwer Source Type: research

Fucoidan from Sargassum wightii reduces oxidative stress through upregulating Nrf2/HO-1 signaling pathway in alloxan-induced diabetic cardiomyopathy rats
CONCLUSION: The current research concludes that targeting oxidative stress with SwF provided an effective role in the prevention of DCM. Thus, fucoidan could be used to develop functional food ingredients for DCM.PMID:37665545 | DOI:10.1007/s11033-023-08780-z
Source: Molecular Biology Reports - September 4, 2023 Category: Molecular Biology Authors: Shanavas Syed Mohamed Puhari Subramani Yuvaraj Varadaraj Vasudevan Tharmarajan Ramprasath Kulanthaiyesu Arunkumar Chinnaiah Amutha Govindan Sadasivam Selvam Source Type: research

Sword Bean (Canavalia gladiata): a new host of Bean common mosaic virus
CONCLUSION: In the present study, BCMV was found to be naturally infecting Sword bean for the first time in the world. This is of epidemiological importance, as BCMV is known to cause significant yield losses in legumes and could severely hamper Sword bean production.PMID:37651019 | DOI:10.1007/s11033-023-08769-8
Source: Molecular Biology Reports - August 31, 2023 Category: Molecular Biology Authors: Raj Verma Abhishek Verma Savarni Tripathi Source Type: research

Assessment of thermal and temporal stability of SARS-CoV-2 samples using real-time qRT-PCR
CONCLUSION: The SARS-CoV-2 genetic materials in commercial VTM were stable at room temperature to -80 °C for 50 days.PMID:37644371 | DOI:10.1007/s11033-023-08740-7
Source: Molecular Biology Reports - August 29, 2023 Category: Molecular Biology Authors: Rohit Kumar Swain S S Mohanty Mahendra Thakor A K Sharma Source Type: research

Epithelial-to-mesenchymal transition status correlated with ultrastructural features, and TP53 mutation in patient-derived oral cancer cell lines
CONCLUSIONS: Cellular migratory properties are associated with cellular ultrastructure, epithelial-to-mesenchymal transition status and the status of TP53 mutation in the genome.PMID:37639153 | DOI:10.1007/s11033-023-08720-x
Source: Molecular Biology Reports - August 28, 2023 Category: Molecular Biology Authors: Sushant S Navarange Sanjay M Bane Darshan Mehta Sanket Shah Sanjay Gupta Sanjeev K Waghmare Source Type: research

< em > Moringa oleifera < /em > : A Review on the Antiproliferative Potential in Breast Cancer Cells
Curr Issues Mol Biol. 2023 Aug 18;45(8):6880-6902. doi: 10.3390/cimb45080434.ABSTRACTThe global burden of female breast cancer and associated deaths has become a major concern. Many chemotherapeutic agents, such as doxorubicin, have been shown to have adverse side effects. The development of multi-drug resistance is a common occurrence, contributing to chemotherapeutic failure. The resistance of breast cancer cells to drug treatment leads to a decline in the treatment efficacy and an increase in cancer recurrence. Therefore, action is required to produce alternative drug therapies, such as herbal drugs. Herbal drugs have b...
Source: Current Issues in Molecular Biology - August 25, 2023 Category: Molecular Biology Authors: Malebogo M Moremane Beynon Abrahams Charlette Tiloke Source Type: research