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Citicoline in acute ischemic stroke: A randomized controlled trial
ConclusionCAISR was the first to evaluate the role of Citicoline, when used immediately after recanalization therapy, when the penumbral tissue is the most susceptible either to be protected from injury or become ischemic. We did not find any significant difference between the Citicoline or placebo arms with respect to either our primary or secondary outcomes.
Source: PLoS One - May 31, 2022 Category: Biomedical Science Authors: Ayush Agarwal Source Type: research

Spectrum of hyperosmolar hyperglycaemic state in neurology practice.
Abstract Background & objectives: Hyperosmolar hyperglycaemic state (HHS) is a medical emergency, but there is a paucity of studies reporting the spectrum of neurological manifestations of HHS. We, therefore, report the neurological spectrum, triggering factors and outcome of HHS in general neurology practice. Methods: The records of the patients with HHS were extracted from computerized hospital information system and those managed currently were prospectively included. The demographic, clinical manifestations, duration of diabetes and precipitating events such as infection, stress and stroke were noted....
Source: The Indian Journal of Medical Research - November 1, 2017 Category: Biomedical Science Authors: Misra UK, Kalita J, Bhoi SK, Dubey D Tags: Indian J Med Res Source Type: research

Benefits & risks of statin therapy for primary prevention of cardiovascular disease in Asian Indians - A population with the highest risk of premature coronary artery disease & diabetes.
Benefits & risks of statin therapy for primary prevention of cardiovascular disease in Asian Indians - A population with the highest risk of premature coronary artery disease & diabetes. Indian J Med Res. 2013 Oct;138(4):461-91 Authors: Enas EA, Kuruvila A, Khanna P, Pitchumoni CS, Mohan V Abstract Several reviews and meta-analyses have demonstrated the incontrovertible benefits of statin therapy in patients with cardiovascular disease (CVD). But the role for statins in primary prevention remained unclear. The updated 2013 Cochrane review has put to rest all lingering doubts about the overwhelming ...
Source: The Indian Journal of Medical Research - October 1, 2013 Category: Biomedical Science Authors: Enas EA, Kuruvila A, Khanna P, Pitchumoni CS, Mohan V Tags: Indian J Med Res Source Type: research

Pattern of cognitive deficits in vascular dementia.
Abstract Background & objectives: There is a paucity of literature on the cognitive profiles of vascular dementia (VaD) in India. The current study was undertaken to investigate the pattern of cognitive deficits in patients with VaD. Methods: Fifty patients fulfilling the Diagnostic and Statistical Manual of Mental Disorders-IV criteria of dementia and National Institute of Neurological Disorders and Stroke - Association Internationale pour la Recherche et l'Enseignement en Neurosciences criteria for VaD were assessed using Mini Mental State Examination, Kolkata Cognitive Screening Battery and other relev...
Source: The Indian Journal of Medical Research - March 31, 2019 Category: Biomedical Science Authors: Sengupta P, Ganguly J, Pal S, Ghosal M Tags: Indian J Med Res Source Type: research

First person - Mohd. Salman FIRST PERSON
ABSTRACT First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping early-career researchers promote themselves alongside their papers. Mohd. Salman is first author on ‘Nrf2/HO-1 mediates the neuroprotective effects of pramipexole by attenuating oxidative damage and mitochondrial perturbation after traumatic brain injury in rats’, published in DMM. Mohd. is a PhD student in the lab of Prof. Suhel Parvez at Jamia Hamdard, New Delhi, India, investigating the cellular and molecular mechanisms involved in traumatic brain injury, ische...
Source: DMM Disease Models and Mechanisms - August 18, 2020 Category: Biomedical Science Tags: FIRST PERSON Source Type: research

Trends in diabetes-related complications in Singapore, 2013 –2020: A registry-based study
ConclusionWe found that DM and its complications represent an important challenge for healthcare in Singapore. Improvements in the trends of DM macrovascular complications were observed. However, trends in DM microvascular complications remain a cause for concern.
Source: PLoS One - October 11, 2022 Category: Biomedical Science Authors: Joshua Kuan Tan Source Type: research

Enablers & amp; challenges of tribal women & amp; health system for implementation of screening of non-communicable diseases & amp; common cancers: A mixed-methods study in Palghar district of Maharashtra, India
CONCLUSIONS: The study recommends incorporating socioculturally relevant strategies in the tribal population and strengthening health facilities in terms of infrastructure and training with involvement of ASHAs for successful implementation of the National Programme for Prevention and Control of Cancer, Diabetes, Cardiovascular Diseases and Stroke (NPCDCS) through health and wellness centres.PMID:36348588 | DOI:10.4103/ijmr.ijmr_3240_21
Source: The Indian Journal of Medical Research - November 9, 2022 Category: Biomedical Science Authors: Shantanu Birje Anushree Devashish Patil Kiran Ramdas Munne Vidya Chavan Beena Nitin Joshi Anamika Akula Neha Salvi Smitha Nair Shahanara Prabhu Valawalkar Deepti Tandon Sanjay Chauhan Devendra Patil Bontha V Babu Source Type: research

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