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Total 70 results found since Jan 2013.

Clinical Characteristics of Pediatric Patients with Congenital Erythrocytosis: A Single-Center Study
AbstractAlthough congenital erythrocytosis (CE), an inherited disorder, impairs pediatric quality of life, physicians often overlook high hemoglobin (Hgb) levels and its symptoms due to lack of knowledge of age-adjusted pediatric Hgb levels and CE ’s rarity. In a retrospective, single-center study, data from hospital records of pediatric patients diagnosed with CE were evaluated. Twenty-six patients from 25 families (80.8% male) had been diagnosed with CE in 20 years, at a mean age of 14.9 ± 2.8 years (8.3–17.8) and with a mean Hgb level of 17.36 ± 1.44 g/dL (14.63–22.1). No serum erythropoietin levels e...
Source: Indian Journal of Hematology and Blood Transfusion - August 25, 2021 Category: Hematology Source Type: research

Capsular Warning Syndrome - A Case Series and Discussion on Management Dilemmas
DISCUSSION: Despite multiple hypotheses, the pathogenesis and management of CWS has not been established clearly. Due to fluctuating neurological symptoms with complete recovery in between the episodes, there is a dilemma concerning treatment of such patients with intravenous thrombolysis. However, intravenous thrombolysis appears to be safe in CWS as in acute ischemic stroke, followed by treatment with antiplatelet agents.PMID:34472813
Source: Journal of the Association of Physicians of India - September 2, 2021 Category: General Medicine Authors: Uma Sundar Pramod Darole Ashank Bansal A Wadal S Gosavi Anagha Joshi Source Type: research

Efficacy of a family-based cardiovascular risk reduction intervention in individuals with a family history of premature coronary heart disease in India (PROLIFIC): an open-label, single-centre, cluster randomised controlled trial
Lancet Glob Health. 2021 Oct;9(10):e1442-e1450. doi: 10.1016/S2214-109X(21)00319-3.ABSTRACTBACKGROUND: Coronary heart disease, a leading cause of death globally, is amenable to lifestyle interventions. The family environment can affect the ability or willingness of individuals to make lifestyle changes. We aimed to investigate the efficacy of a targeted family-based intervention for reduction of total cardiovascular risk in individuals with a family history of premature coronary heart disease.METHODS: We did an open-label, cluster randomised controlled trial (PROLIFIC) in the families (first-degree relatives and spouses, o...
Source: Australian Family Physician - September 17, 2021 Category: Primary Care Authors: Panniyammakal Jeemon Sivadasanpillai Harikrishnan Sanjay Ganapathi Sivasubramonian Sivasankaran Bhaskarapillai Binukumar Sandosh Padmanabhan Nikhil Tandon Dorairaj Prabhakaran Source Type: research

Capsular Warning Syndrome - A Case Series and Discussion on Management Dilemmas
DISCUSSION: Despite multiple hypotheses, the pathogenesis and management of CWS has not been established clearly. Due to fluctuating neurological symptoms with complete recovery in between the episodes, there is a dilemma concerning treatment of such patients with intravenous thrombolysis. However, intravenous thrombolysis appears to be safe in CWS as in acute ischemic stroke, followed by treatment with antiplatelet agents.PMID:34472813
Source: Journal of the Association of Physicians of India - September 2, 2021 Category: General Medicine Authors: Uma Sundar Pramod Darole Ashank Bansal A Wadal S Gosavi Anagha Joshi Source Type: research

Efficacy of a family-based cardiovascular risk reduction intervention in individuals with a family history of premature coronary heart disease in India (PROLIFIC): an open-label, single-centre, cluster randomised controlled trial
Lancet Glob Health. 2021 Oct;9(10):e1442-e1450. doi: 10.1016/S2214-109X(21)00319-3.ABSTRACTBACKGROUND: Coronary heart disease, a leading cause of death globally, is amenable to lifestyle interventions. The family environment can affect the ability or willingness of individuals to make lifestyle changes. We aimed to investigate the efficacy of a targeted family-based intervention for reduction of total cardiovascular risk in individuals with a family history of premature coronary heart disease.METHODS: We did an open-label, cluster randomised controlled trial (PROLIFIC) in the families (first-degree relatives and spouses, o...
Source: Australian Family Physician - September 17, 2021 Category: Primary Care Authors: Panniyammakal Jeemon Sivadasanpillai Harikrishnan Sanjay Ganapathi Sivasubramonian Sivasankaran Bhaskarapillai Binukumar Sandosh Padmanabhan Nikhil Tandon Dorairaj Prabhakaran Source Type: research

Capsular Warning Syndrome - A Case Series and Discussion on Management Dilemmas
DISCUSSION: Despite multiple hypotheses, the pathogenesis and management of CWS has not been established clearly. Due to fluctuating neurological symptoms with complete recovery in between the episodes, there is a dilemma concerning treatment of such patients with intravenous thrombolysis. However, intravenous thrombolysis appears to be safe in CWS as in acute ischemic stroke, followed by treatment with antiplatelet agents.PMID:34472813
Source: Journal of the Association of Physicians of India - September 2, 2021 Category: General Medicine Authors: Uma Sundar Pramod Darole Ashank Bansal A Wadal S Gosavi Anagha Joshi Source Type: research

Efficacy of a family-based cardiovascular risk reduction intervention in individuals with a family history of premature coronary heart disease in India (PROLIFIC): an open-label, single-centre, cluster randomised controlled trial
Lancet Glob Health. 2021 Oct;9(10):e1442-e1450. doi: 10.1016/S2214-109X(21)00319-3.ABSTRACTBACKGROUND: Coronary heart disease, a leading cause of death globally, is amenable to lifestyle interventions. The family environment can affect the ability or willingness of individuals to make lifestyle changes. We aimed to investigate the efficacy of a targeted family-based intervention for reduction of total cardiovascular risk in individuals with a family history of premature coronary heart disease.METHODS: We did an open-label, cluster randomised controlled trial (PROLIFIC) in the families (first-degree relatives and spouses, o...
Source: Australian Family Physician - September 17, 2021 Category: Primary Care Authors: Panniyammakal Jeemon Sivadasanpillai Harikrishnan Sanjay Ganapathi Sivasubramonian Sivasankaran Bhaskarapillai Binukumar Sandosh Padmanabhan Nikhil Tandon Dorairaj Prabhakaran Source Type: research