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Safety and Immunogenicity of Radiation-Attenuated PfSPZ Vaccine in Equatoguinean Infants, Children, and Adults
Am J Trop Med Hyg. 2023 May 9:tpmd220773. doi: 10.4269/ajtmh.22-0773. Online ahead of print.ABSTRACTThe radiation-attenuated Plasmodium falciparum sporozoites (PfSPZ) Vaccine has demonstrated safety and immunogenicity in 5-month-old to 50-year-old Africans in multiple trials. Except for one, each trial has restricted enrollment to either infants and children or adults < 50 years old. This trial was conducted in Equatorial Guinea and assessed the safety, tolerability, and immunogenicity of three direct venous inoculations of 1.8 × 106 or 2.7 × 106 PfSPZ, of PfSPZ Vaccine, or normal saline administered at 8-week interva...
Source: The American Journal of Tropical Medicine and Hygiene - May 9, 2023 Category: Tropical Medicine Authors: Said A Jongo Vicente Urbano Nsue Ndong Nchama L W Preston Church Ally Olotu Stephen R Manock Tobias Schindler Ali Mtoro Natasha Kc Orrin Devinsky Elcin Zan Ali Hamad Elizabeth Nyakarungu Maxmillian Mpina Anna Deal Jos é Raso Bijeri Martin Eka Ondo Mangue Source Type: research

Philanthropists Join Forces to Fund Africa ’s Cash-Strapped Health Sector
Tristate Heart and Vascular Centre in Nigeria. Credit: Tristate Heart and Vascular CentreBy Pavithra Rao, Africa Renewal*NEW YORK, Sep 28 2017 (IPS)In the 2017 World Happiness Report by Gallup, African countries score poorly. Of the 150 countries on the list, the Central African Republic, Tanzania and Burundi rank as the unhappiest countries in the world. Some of the factors driving unhappiness are the poor state of the continent’s health care systems, the persistence of HIV/AIDS, malaria and tuberculosis, and the growth of lifestyle diseases such as hypertension, heart disease and diabetes.Few African countries make sig...
Source: IPS Inter Press Service - Health - September 28, 2017 Category: International Medicine & Public Health Authors: Pavithra Rao Tags: Development & Aid Featured Global Headlines Health TerraViva United Nations Source Type: news