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Genetic loci, rs17817449 and rs6567160, known for obesity and the risk of stroke events among middle-aged and older Chinese people
ConclusionThe G allele of rs17817449 at the FTO, not rs6567160 at the MC4R, was associated with a decreased risk of fatal stroke occurrence; its functional role in stroke should be explored in relatively healthy middle-aged to older Chinese people.
Source: Frontiers in Neurology - December 2, 2022 Category: Neurology Source Type: research

Modulations of static and dynamic functional connectivity among brain networks by electroacupuncture in post-stroke aphasia
This study aimed to investigate the PSA-related effects of EA stimulation at HT5 and GB39 on neural processing. Thirty-five participants were recruited, including 19 patients with PSA and 16 healthy controls (HCs). The BOLD signal was analyzed by static independent component analysis, generalized psychophysiological interactions, and dynamic independent component analysis, considering variables such as age, sex, and years of education.ResultsThe results revealed that PSA showed activated clusters in the left putamen, left postcentral gyrus (PostCG), and left angular gyrus in the salience network (SN) compared to the HC gro...
Source: Frontiers in Neurology - December 1, 2022 Category: Neurology Source Type: research

Effects of 12 Weeks of Tai Chi Chuan Intervention on the balance and ankle instability in subjects with functional ankle instability: study protocol for a randomized controlled trial
This study will be a single-centre, parallel group, randomized controlled trial. Sixty-eight FAI patients will be included and randomly assigned in a 1:1 ratio to either an intervention group (n =34) or a control group (n=34). The participants in the intervention group will complete twelve weeks of TCC intervention (40min/time, 3 times/week, for 12 weeks) on the basis of health education treatment. The control group will receive health education and 36 conventional balance training sessions during a 12-week period. Outcome measures include postural stability and self-reported feelings of instability at baseline, after the ...
Source: Frontiers in Neurology - September 21, 2022 Category: Neurology Source Type: research

Effects of 12 weeks of Tai Chi Chuan intervention on the postural stability and self-reported instability in subjects with functional ankle instability: Study protocol for a randomized controlled trial
This study will be a single-center, parallel group, randomized controlled trial. Sixty-eight patients with FAI will be included and randomly assigned in a 1:1 ratio to either an intervention group (n =34) or a control group (n = 34). The participants in the intervention group will complete 12 weeks of TCC intervention (40 min/time, 3 times/week for 12 weeks) on the basis of health education treatment. The control group will receive health education and 36 CBT sessions during a 12-week period. Outcome measures include postural stability and self-reported feelings of instability at baseline, after the end of the intervention...
Source: Frontiers in Neurology - September 21, 2022 Category: Neurology Source Type: research

Blood pressure control and risk of post-stroke dementia among the elderly: A population-based screening study
ConclusionsThe crude prevalence of PSD among stroke survivors aged ≥65 years was 17.8% at community level. In addition to lower education level and older age, poorly-controlled blood pressure was also an independent risk factor for PSD among the elderly, which is amenable to intervention. Therefore, it is essential to control blood pressure to reduce PSD incidence.
Source: Frontiers in Neurology - August 9, 2022 Category: Neurology Source Type: research

How do cardiovascular risk factors correlate with post-stroke cognitive function: Directly or indirectly through stroke severity?
ConclusionThis is the first Chinese study exploring the moderated and mediating associations between cardiovascular risk factors, stroke severity, and cognitive function after stroke. Age, female sex, and atrial fibrillation were directly associated with lower cognition after stroke. The combination of hypertension might have a positive effect on cognition.
Source: Frontiers in Neurology - August 5, 2022 Category: Neurology Source Type: research

Persistence of drug therapy is associated with ischemic stroke and other vascular events in high-risk stroke population
The high-risk stroke populations are significantly associated with an increased risk of stroke or other vascular events. Although proven primary and secondary stroke prevention medications are available, persistent use is required to be effective. However, the persistence of drug therapy and its association with outcomes in the high-risk stroke population have received limited study in China. Hence, according to the China National Stroke Screening Survey (CNSSS) program in 2015, we performed this multicenter population-based cross-sectional survey and prospective cohort study in Sichuan of southwestern China. The residents...
Source: Frontiers in Neurology - July 25, 2022 Category: Neurology Source Type: research

Relationship Between Lipoprotein (a) Lp(a) and Cognition in Different Ischemic Stroke Subtypes
Conclusion: Higher Lp(a) level was associated with cognitive impairment and less improvement of cognition in patients after AIS or TIA with large-artery atherosclerosis subtype.
Source: Frontiers in Neurology - December 3, 2021 Category: Neurology Source Type: research

Age-Related Disparities in Stroke Knowledge Among Community Older Adults
Conclusion: The older adults and the oldest old had significantly high disparities in stroke knowledge. Given the aging population across China, the life expectancy is expected to be longer in future decades. These differences should be addressed in stroke educational campaigns targeting the oldest old.
Source: Frontiers in Neurology - September 8, 2021 Category: Neurology Source Type: research

Risk Factors Influencing Seeking Emergency Medical Service in Urban and Rural China Among Participants With a Previous Transient Ischemic Attack
Conclusions: Rural residents with previous TIA in China had a higher percentage of not calling EMS. Multiple risk factors have been identified that call for targeted intervention strategies.
Source: Frontiers in Neurology - February 4, 2021 Category: Neurology Source Type: research

Comparison of the Characteristics and Risk Factors of Carotid Atherosclerosis in High Stroke Risk Populations Between Urban and Rural Areas in North China
Conclusion: This study suggests that risk factors for carotid atherosclerosis differ between urban and rural populations in North China.
Source: Frontiers in Neurology - November 9, 2020 Category: Neurology Source Type: research

Middle School Students Effectively Improve Stroke Knowledge and Pass Them to Family Members in China Using Stroke 1-2-0
Conclusion: Middle school and high school students can effectively use Stroke 1-2-0 to improve their stroke knowledge and pass this knowledge to their family members. Sustained educational efforts and repeated educational events are needed though.
Source: Frontiers in Neurology - April 7, 2020 Category: Neurology Source Type: research

Positive Influence of Stroke Health Manager on Risk Factors Control and Medication Adherence After Ischemic Stroke
Conclusions: Stroke health manager intervention improved the control of blood pressure, LDL-C, glucose levels and the persistence for secondary prevention medications 3 months after discharge.
Source: Frontiers in Neurology - March 10, 2020 Category: Neurology Source Type: research

Rate and Determinants of Recurrence at 1 Year and 5 Years After Stroke in a Low-Income Population in Rural China
Recurrent stroke is becoming an increasingly important public health issue owing to the increased risk of disability and death. However, population-based studies investigating the rate of recurrent stroke in China are rare. We explored the rate and determinants of recurrent stroke within 1 and 5 years after the initial stroke in a rural population in China. Data for stroke events were obtained from the Tianjin Brain Study, conducted between 1992 and 2016. The age-standardized rates of recurrent stroke within the first year and the first 5 years after the initial stroke were calculated for this period. Determinants of recur...
Source: Frontiers in Neurology - January 22, 2020 Category: Neurology Source Type: research

Age- and Sex-Associated Impacts of Body Mass Index on Stroke Type Risk: A 27-Year Prospective Cohort Study in a Low-Income Population in China
Conclusions Being overweight increased the risk of both ischemic and hemorrhagic strokes; obesity was only associated with an increased risk of IS. Additionally, the positive association between BMI and stroke risk was only observed in participants aged <65 years and the associations differed between men and women. Being overweight increased the risk of both ischemic and hemorrhagic strokes in men and being underweight increased their risk of hemorrhagic stroke. In women, being overweight increased the hemorrhagic stroke risk, whereas obesity increased their IS risks. The high prevalence of hypertension and elevat...
Source: Frontiers in Neurology - April 30, 2019 Category: Neurology Source Type: research

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