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Specialty: Gastroenterology
Therapy: Statin Therapy
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Total 153 results found since Jan 2013.
Lipophilic statins inhibit YAP co-activator transcriptional activity in HCC cells through Rho-mediated modulation of the actin cytoskeleton
Conclusions: YAP protein localization is regulated by lipophilic statins via Rho GTPases causing cytoskeletal structural changes and is independent of cholesterol metabolites.PMID:37366601 | DOI:10.1152/ajpgi.00089.2023
Source: Am J Physiol Gastroi... - June 27, 2023 Category: Gastroenterology Authors: Jihane N Benhammou Bo Qiao Arthur Ko James Sinnett-Smith Joseph Pisegna Enrique Rozengurt Source Type: research
Evolution of care in cirrhosis: Preventing hepatic decompensation through pharmacotherapy
This report highlights the potential impact of these agents and others in preventing hepatic decompensation and discusses how this paradigm shift may pave the way for guideline-directed medical therapy in cirrhosis.PMID:36683719 | PMC:PMC9850948 | DOI:10.3748/wjg.v29.i1.61
Source: World Journal of Gastroenterology : WJG - January 23, 2023 Category: Gastroenterology Authors: Seohyuk Lee Saad Saffo Source Type: research
