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Total 1048 results found since Jan 2013.
< em > Naoluo Xintong < /em > Decoction activates caspase-1/Gasdermin D pathway to promote angiogenesis of rat brain microvascular endothelial cells after oxygen glucose deprivation/reperfusion injury
CONCLUSION: NLXTD can improve the proliferation, migration, and tube- forming ability and promote angiogenesis of BMECs with OGD/R injury probably by inhibiting the caspase-1/Gasdermin D pathway in pyroptosis, alleviating cell injury, and upregulating the expressions of VEGF and VEGFR2.PMID:37488791 | PMC:PMC10366515 | DOI:10.12122/j.issn.1673-4254.2023.07.05
Source: Journal of Southern Medical University - July 25, 2023 Category: Universities & Medical Training Authors: P Li Y Hu J Liu L Wang Y Wu J Hu Source Type: research
Lactate-induced up-regulation of PLEKHA4 promotes proliferation and apoptosis of human glioma cells
CONCLUSION: PLEKHA4 knockdown inhibited the proliferation of glioma cells and promoted apoptosis by inhibiting the activation of the MAPK signaling pathway and expression of β-catenin. Lactic acid produced by glycolysis upregulates the expression of PLEKHA4 in glioma cells.PMID:37488789 | PMC:PMC10366507 | DOI:10.12122/j.issn.1673-4254.2023.07.03
Source: Journal of Southern Medical University - July 25, 2023 Category: Universities & Medical Training Authors: J Ye W Xu B Xi N Wang T Chen Source Type: research
< em > Naoluo Xintong < /em > Decoction activates caspase-1/Gasdermin D pathway to promote angiogenesis of rat brain microvascular endothelial cells after oxygen glucose deprivation/reperfusion injury
CONCLUSION: NLXTD can improve the proliferation, migration, and tube- forming ability and promote angiogenesis of BMECs with OGD/R injury probably by inhibiting the caspase-1/Gasdermin D pathway in pyroptosis, alleviating cell injury, and upregulating the expressions of VEGF and VEGFR2.PMID:37488791 | PMC:PMC10366515 | DOI:10.12122/j.issn.1673-4254.2023.07.05
Source: Journal of Southern Medical University - July 25, 2023 Category: Universities & Medical Training Authors: P Li Y Hu J Liu L Wang Y Wu J Hu Source Type: research
Lactate-induced up-regulation of PLEKHA4 promotes proliferation and apoptosis of human glioma cells
CONCLUSION: PLEKHA4 knockdown inhibited the proliferation of glioma cells and promoted apoptosis by inhibiting the activation of the MAPK signaling pathway and expression of β-catenin. Lactic acid produced by glycolysis upregulates the expression of PLEKHA4 in glioma cells.PMID:37488789 | PMC:PMC10366507 | DOI:10.12122/j.issn.1673-4254.2023.07.03
Source: Journal of Southern Medical University - July 25, 2023 Category: Universities & Medical Training Authors: J Ye W Xu B Xi N Wang T Chen Source Type: research
< em > Naoluo Xintong < /em > Decoction activates caspase-1/Gasdermin D pathway to promote angiogenesis of rat brain microvascular endothelial cells after oxygen glucose deprivation/reperfusion injury
CONCLUSION: NLXTD can improve the proliferation, migration, and tube- forming ability and promote angiogenesis of BMECs with OGD/R injury probably by inhibiting the caspase-1/Gasdermin D pathway in pyroptosis, alleviating cell injury, and upregulating the expressions of VEGF and VEGFR2.PMID:37488791 | PMC:PMC10366515 | DOI:10.12122/j.issn.1673-4254.2023.07.05
Source: Journal of Southern Medical University - July 25, 2023 Category: Universities & Medical Training Authors: P Li Y Hu J Liu L Wang Y Wu J Hu Source Type: research
Lactate-induced up-regulation of PLEKHA4 promotes proliferation and apoptosis of human glioma cells
CONCLUSION: PLEKHA4 knockdown inhibited the proliferation of glioma cells and promoted apoptosis by inhibiting the activation of the MAPK signaling pathway and expression of β-catenin. Lactic acid produced by glycolysis upregulates the expression of PLEKHA4 in glioma cells.PMID:37488789 | PMC:PMC10366507 | DOI:10.12122/j.issn.1673-4254.2023.07.03
Source: Journal of Southern Medical University - July 25, 2023 Category: Universities & Medical Training Authors: J Ye W Xu B Xi N Wang T Chen Source Type: research
Dentin Matrix Protein 1 Regulates Mineralization of MC3T3-E1 Cells via the TNAP-ANK-ENPP1 Axis
CONCLUSIONS: DMP1 regulated mineralization of MC3T3-E1 cells via the TNAP-ANK-ENPP1 axis and affected TNAP activity by two processes-rapid regulation of the Zn2+ transporter (ZnT) and transcriptional regulation of hysteresis. However, DMP1 may affect expression of ENPP1 and ANK only via hysteresis transcriptional regulation. DMP1, as a calcium trap or catalytic enzyme, appears to have a role in collagen mineralization.PMID:37380477 | DOI:10.1272/jnms.JNMS.2023_90-306
Source: Journal of Nippon Medical School - June 28, 2023 Category: Universities & Medical Training Authors: Jianmin Liu Juhua Zhao Zhi Li Hongmei Wang Binbin Wang Wei Liu Lei Zhou Source Type: research
