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Specialty: Environmental Health
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Total 205 results found since Jan 2013.
Acute exposure to PM < sub > 2.5 < /sub > triggers lung inflammatory response and apoptosis in rat
Ecotoxicol Environ Saf. 2021 Jul 21;222:112526. doi: 10.1016/j.ecoenv.2021.112526. Online ahead of print.ABSTRACTSevere haze events, especially with high concentration of fine particulate matter (PM2.5), are frequent in China, which have gained increasing attention among public. The purpose of our study was explored the toxic effects and potential damage mechanisms about PM2.5 acute exposure. Here, the diverse dosages of PM2.5 were used to treat SD rats and human bronchial epithelial cell (BEAS-2B) for 24 h, and then the bioassays were performed at the end of exposure. The results show that acute exposure to diverse dosage...
Source: Ecotoxicology and Environmental Safety - July 24, 2021 Category: Environmental Health Authors: Yang Li Josevata Werelagi Batibawa Zhou Du Shuang Liang Junchao Duan Zhiwei Sun Source Type: research
The role of NLRP3 in lead-induced neuroinflammation and possible underlying mechanism
CONCLUSIONS: NLRP3 is involved in the regulation of Pb-induced neurotoxicity. These findings expand mechanism research of Pb neurotoxicity and may help establish new prevention strategies for Pb neurotoxicity.PMID:34182382 | DOI:10.1016/j.envpol.2021.117520
Source: Environmental Pollution - June 28, 2021 Category: Environmental Health Authors: Peng Su Diya Wang Zipeng Cao Jingyuan Chen Jianbin Zhang Source Type: research
Screening and functional verification of the target protein of pedunsaponin A in the killing of Pomacea canaliculata
This study lays the foundation for further exploration of the molecular mechanism by which PA kills this harmful snail.PMID:34098426 | DOI:10.1016/j.ecoenv.2021.112393
Source: Ecotoxicology and Environmental Safety - June 7, 2021 Category: Environmental Health Authors: Chunping Yang Yangyang Zhang Yue Zhou Huabao Chen Tianxing Lv Liya Luo Xiaoyan Qiu Min Zhang Guangwei Qin Guoshu Gong Source Type: research
SET Domain-Containing Protein 5 Enhances the Cell Stemness of Non-Small Cell Lung Cancer via the PI3K/Akt/mTOR Pathway
CONCLUSION: In this study, SETD5 promoted the cancer stem cell property of NSCLC through mitigating the activation of the PI3K/Akt/mTOR pathway, suggesting a candidate target role for SETD5 in NSCLC treatment.PMID:33822517 | DOI:10.1615/JEnvironPatholToxicolOncol.2021036991
Source: Journal of Environmental Pathology, Toxicology and Oncology - April 6, 2021 Category: Environmental Health Authors: Qing Chen Zhuo Sun Jinfang Li Donghua Zhang Bin Guo Tongwen Zhang Source Type: research
