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JMM Profile: Sindbis virus, a cause of febrile illness and arthralgia
J Med Microbiol. 2023 Mar;72(3). doi: 10.1099/jmm.0.001674.ABSTRACTSindbis virus (SINV) is the causative agent of a febrile infection commonly called Ockelbo disease, Pogosta disease or Karelian fever in northern Europe. Finland, Sweden, Russia and South Africa experience periodic SINV outbreaks. SINV is classified within the family Togaviridae and genus Alphavirus. Symptoms of SINV infection in humans include joint inflammation and pain, fever, rash and fatigue. In some cases, joint symptoms can persist for years after recovery from the initial infection. Clinical signs of SINV infection are rarely reported in animals, al...
Source: Journal of Medical Microbiology - March 21, 2023 Category: Microbiology Authors: Sophie Harding Sanam Sewgobind Nicholas Johnson Source Type: research

Vaccination with celecoxib-treated dendritic cells improved cellular immune responses in an animal breast cancer model
CONCLUSIONS: Our findings show that LPS/CXB-treated DC vaccine potently modulated antitumor immune responses in a mouse BC model.PMID:37003235 | DOI:10.1016/j.advms.2023.03.002
Source: Advances in Medical Sciences - April 1, 2023 Category: Biomedical Science Authors: Raziyeh Zandvakili Pedram Basirjafar Javad Masoumi Nahid Zainodini Zahra Taghipour Hossein Khorramdelazad Soheila Yousefi Tayyebeh Tavakoli Sepehr Safdel Mahsa Gheitasi Fatemeh Ayoobi Abdollah Jafarzadeh Source Type: research