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Early cardiac rehabilitation after heart transplantation in a patient with limb-girdle muscular dystrophy: A case report
Rationale: Cardiac rehabilitation (CR) after heart transplantation (HT) decreases the mortality rate and increases exercise capacity of patients. Dilated cardiomyopathy develops in most patients with muscular dystrophy (MD), leading to advanced heart failure, necessitating the use of left ventricular assist devices or HT. As the clinical outcomes of left ventricular assist devices and HT in patients with myopathy differ from those in patients without myopathy, CR adapted to patients with MD should be considered. Patient concerns: A 39-year-old man with limb-girdle muscular dystrophy developed dilated cardiomyopa...
Source: Medicine - July 29, 2022 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

Primary carnitine deficiency – diagnosis after heart transplantation: better late than never!
Primary carnitine deficiency due to mutations in the SLC22A5 gene is a rare but well-treatable metabolic disorder that puts patients at risk for metabolic decompensations, skeletal and cardiac myopathy and sudden...
Source: Orphanet Journal of Rare Diseases - April 10, 2020 Category: Internal Medicine Authors: Sarah C. Gr ünert, Sara Tucci, Anke Schumann, Meike Schwendt, Gwendolyn Gramer, Georg F. Hoffmann, Michelle Erbel, Brigitte Stiller and Ute Spiekerkoetter Tags: Research Source Type: research

A case report of cyclosporine-induced myopathy with subacute muscular atrophy as initial presentation
Rationale: Cyclosporine A (CsA) is a potent immunosuppressive agent originally used to prevent rejection after organ transplantation but now more frequently used for treatment of refractory autoimmune diseases. It can induce adverse effects, such as nephrotoxicity, gastrointestinal reactions, and gingival hyperplasia whist myopathy with subacute muscular atrophy are rare. Patient concerns: A 55-year-old male patient with idiopathic membranous nephropathy treated with cyclosporine A at 3 mg/kg/d and prednisone at 0.5 mg/kg.d for more than 20 days, gradually developed lower limb weakness, which were progressively ag...
Source: Medicine - April 1, 2019 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

Inflammatory myopathies after allogeneic stem cell transplantation
Discussion: Among recipients of allo ‐SCT, weakness is common, and the incidence of IM is increased. Histopathological diagnoses are varied, and we report findings of necrotizing myopathy and anti‐MDA5‐associated DM.Muscle Nerve, 2018
Source: Muscle and Nerve - November 20, 2018 Category: Internal Medicine Authors: Julia New ‐Tolley, Caroline Smith, Barbara Koszyca, Sophia Otto, Adam Maundrell, Peter Bardy, Devendra Hiwase, Agnes S. M. Yong, Ian Lewis, Vidya Limaye Tags: Clinical Research Source Type: research

Ischemic myopathy revealing systemic calciphylaxis
This article is protected by copyright. All rights reserved.
Source: Muscle and Nerve - December 8, 2016 Category: Internal Medicine Authors: Jessie Aouizerate, Laurence Valleyrie ‐Allanore, Nicolas Limal, S. Samar Ayache, Romain K. Gherardi, Vincent Audard, François Jérôme Authier Tags: Research Article Source Type: research

Sporadic late‐onset nemaline myopathy as a rare cause of slowly progressive muscle weakness with young adult onset
Conclusions: Considering the recent reports of successful treatment of SLONM, early and correct diagnosis of SLONM associated with monoclonal gammopathy is important. SLONM should be added to the list of diseases to consider in the differential diagnosis of progressive muscle weakness with young adult onset. © 2014 Wiley Periodicals, Inc.
Source: Muscle and Nerve - November 1, 2014 Category: Internal Medicine Authors: Meiko Hashimoto Maeda, Hikari Ohta, Koji Izutsu, Jun Shimizu, Yoshikazu Uesaka Tags: Case of the Month Source Type: research

Sporadic late onset nemaline myopathy and immunoglobulin deposition disease
Discussion: We speculate that deposition of light and heavy chains, rather than nemaline bodies, has myotoxic effects on skeletal muscle. © 2013 Wiley Periodicals, Inc.
Source: Muscle and Nerve - July 19, 2013 Category: Internal Medicine Authors: Kathrin Doppler, Stefan Knop, Hermann Einsele, Claudia Sommer, Carsten Wessig Tags: Case of the Month Source Type: research

Barth syndrome
First described in 1983, Barth syndrome (BTHS) is widely regarded as a rare X-linked genetic disease characterised by cardiomyopathy (CM), skeletal myopathy, growth delay, neutropenia and increased urinary excretion of 3-methylglutaconic acid (3-MGCA). Fewer than 200 living males are known worldwide, but evidence is accumulating that the disorder is substantially under-diagnosed. Clinical features include variable combinations of the following wide spectrum: dilated cardiomyopathy (DCM), hypertrophic cardiomyopathy (HCM), endocardial fibroelastosis (EFE), left ventricular non-compaction (LVNC), ventricular arrhythmia, sudd...
Source: Orphanet Journal of Rare Diseases - February 12, 2013 Category: Internal Medicine Authors: Sarah ClarkeAnn BowronIris GonzalezSarah GrovesRuth Newbury-EcobNicol ClaytonRobin MartinBeverly Tsai-GoodmanVanessa GarrattMichael AshworthValerie BowenKatherine McCurdyMichaela DaminCarolyn SpencerMatthew TothRichard KelleyColin Steward Source Type: research