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An Exploratory Study on Physical Function in Stem Cell Transplant Patients Undergoing Corticosteroid Treatment for Acute Graft-Versus-Host-Disease
In conclusion, stem cell transplant patients receiving high-dose corticosteroids for acute graft-versus-host disease are at risk for weakness detected as early as day 14. Increasing adherence to exercise may mitigate these changes.
Source: American Journal of Physical Medicine and Rehabilitation - March 20, 2021 Category: Rehabilitation Tags: Brief Report Source Type: research

Changes in Physical Function in Stem Cell Transplant Patients at Risk for Steroid Myopathy
To describe the change in functional tests over time in patients who received an allogeneic hematopoietic stem cell transplant (HSCT) with acute graft-versus-host disease (GVHD) who are at risk for steroid myopathy.
Source: Archives of Physical Medicine and Rehabilitation - November 21, 2018 Category: Rehabilitation Authors: An Ngo-Huang, Rajesh Yadav, Swati Bansal, Janet Williams, Diane Liu, Jimin Wu, Amin Alousi, Jack Fu, Eduardo Bruera Tags: Research poster Source Type: research

Rehabilitation in Chronic Graft-Versus-Host Disease
Chronic graft-versus-host disease is a potentially debilitating complication of allogeneic hematopoietic stem cell transplantation. Due to the direct inflammatory effects of the disease on tissue, and the impact on muscle and bone of the high-dose glucocorticoid immunosuppression used to treat the disease, patients are at risk of developing multifactorial functional impairment. This review outlines the clinical assessment and rehabilitation interventions to manage aspects of the disease that cause the most impairment: involvement of the skin/fascial and cardiopulmonary organ systems, as well as steroid-induced myopathy and...
Source: Physical Medicine and Rehabilitation Clinics of North America - November 30, 2016 Category: Rehabilitation Authors: Sean Robinson Smith, Arash Asher Source Type: research