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Total 214 results found since Jan 2013.
Gadopentetate meglumine activates mast cells to cause IgE-independent allergic reactions both in vitro and in vivo
In this study, the effects of Gd-DTPA in causing allergic like reactions and mast cells (MCs) activation were investigated both in vitro and in vivo. Gd-DTPA induced a severe hand paw swelling and body temperature decrease in murine topical cutaneous allergy model, and murine systemic allergy model. Meanwhile, serum IgE was not significantly changed. Histamine, tryptase, and cytokines release in mice serum and LAD2 cells supernatant were increased significantly both in mice serum and LAD2 supernatant after treated with Gd-DTPA. Subsequently, the changes in mRNA levels after Gd-DTPA activated MCs were analyzed by RNAseq and...
Source: International Immunopharmacology - February 8, 2022 Category: Allergy & Immunology Authors: Xin Liu Yufei Zhang Xu Cui Ting Fan Jin Shu Hui Li Xiaojing Huo Chao Lu Source Type: research
Reversible and multiphasic parenchymal changes in MRI after coil embolization for a ruptured cerebral aneurysm
CONCLUSION: Given her history of metal allergy, and the reversible and multiphasic lesions in the non-vascular territories of the treated aneurysm, metal allergic encephalitis was most likely despite no clear evidence.PMID:37151465 | PMC:PMC10159284 | DOI:10.25259/SNI_160_2023
Source: Surgical Neurology International - May 8, 2023 Category: Neurosurgery Authors: Shinya Miyamoto Hajime Nishido Yasushi Ino Katsumi Hoya Source Type: research
