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Total 2815 results found since Jan 2013.

Surgical treatment of nasal polyposis: A comparison between cutting forceps and microdebrider.
CONCLUSION: The manual instrument allowed for a significantly lower recurrence incidence but yielded a higher rate of synechia formation compared with the microdebrider. Only asthma was significantly associated with a poorer clinical outcome, and gender, age, allergy, and eosinophilia did not affect the surgical prognosis. PMID: 24274215 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - November 1, 2013 Category: ENT & OMF Authors: Tirelli G, Gatto A, Spinato G, Tofanelli M Tags: Am J Rhinol Allergy Source Type: research

Grass pollen sublingual immunotherapy: A double-blind, placebo-controlled study in elderly patients with seasonal allergic rhinitis.
CONCLUSIONS: SLIT in elderly patients with a grass pollen allergy generated a significant clinical improvement in the active group compared with the placebo group for grass pollen season. This therapy was well tolerated. PMID: 25198030 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - September 1, 2014 Category: ENT & OMF Authors: Bozek A, Kolodziejczyk K, Warkocka-Szoltysek B, Jarzab J Tags: Am J Rhinol Allergy Source Type: research

Elevated total serum IgE in nonatopic patients with aspirin-exacerbated respiratory disease.
CONCLUSION: In a subset of patients with AERD, we observed elevated total serum IgE even when atopy was not present. To better understand the disease, the cause and clinical relevance of this phenomenon deserves further exploration. PMID: 25197914 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - July 1, 2014 Category: ENT & OMF Authors: Johns CB, Laidlaw TM Tags: Am J Rhinol Allergy Source Type: research

Identification of the cold receptor TRPM8 in the nasal mucosa.
CONCLUSIONS: The finding of the TRPM8 immunoreactivity underlines the important physiologic role of the nose in temperature regulation, both in patients with allergy and those without allergy. Isometric contraction studies demonstrate the role of TRPM8 in regulating nasal patency and airway resistance. The antiadrenergic effect of menthol showed an effect apparently opposite that of clinical observations, that we usually feel decongested after menthol inhalation. The underlying mechanisms deserve further investigation, and the TRPM8 antagonists deserve consideration for treatment of rhinitis in a therapeutic trial. PM...
Source: American Journal of Rhinology and Allergy - July 1, 2015 Category: ENT & OMF Authors: Liu SC, Lu HH, Cheng LH, Chu YH, Lee FP, Wu CC, Wang HW Tags: Am J Rhinol Allergy Source Type: research

Skin testing versus in vitro testing in the evaluation of aeroallergy: The great debate.
Abstract When one examines reviews regarding diagnostic allergy testing, it generally is noted that the advantage of skin testing is that it uses testing to an end organ, is less expensive, is more sensitive, and provides immediate results, which are easily visualized by the patient. In the case of in vitro testing, it is thought to be more helpful for patients with dermographia or widespread dermatitis, is not affected by H1 or H2 antagonists, and is thought to be safer than skin testing. This may not be entirely correct because studies actually demonstrated phlebotomy to be associated with more morbidity than sk...
Source: American Journal of Rhinology and Allergy - September 1, 2015 Category: ENT & OMF Authors: Oppenheimer J Tags: Am J Rhinol Allergy Source Type: research

Serum indolamine 2,3 dioxygenase as a marker in the evaluation of allergic rhinitis.
CONCLUSION: IDO plays an important role in patients with atopic symptomatic allergic rhinitis, especially with increased levels of IgE. There is no relationship between IDO levels and severity of disease. PMID: 26358342 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - September 1, 2015 Category: ENT & OMF Authors: Refaat MM, Abdel Rehim AS, El-Sayed HM, Mohamed NA, Khafagy AG Tags: Am J Rhinol Allergy Source Type: research

Local allergic rhinitis to pollens is underdiagnosed in young patients.
CONCLUSION: LAR is a serious problem in young patients; however, its significance is still unappreciated. PMID: 28124640 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - October 31, 2016 Category: ENT & OMF Authors: Krajewska-Wojtys A, Jarzab J, Gawlik R, Bozek A Tags: Am J Rhinol Allergy Source Type: research

High Histamine Control Concentration Leads to False Negative Allergy Skin Testing
CONCLUSION: Our study shows that 6 mg/ml concentration of histamine control reagent may contribute to a false interpretation of aeroallergen skin prick test results.PMID:33827292 | DOI:10.1177/19458924211008685
Source: American Journal of Rhinology and Allergy - April 8, 2021 Category: ENT & OMF Authors: Amulya Amirneni Jody Tversky Source Type: research

Therapeutic equivalence of triamcinolone acetonide hydrofluoroalkane and chlorofluorocarbon nasal inhalers in patients with seasonal allergic rhinitis.
CONCLUSION: In conclusion, a new formulation of TAA with a HFA propellant was found to be effective in the treatment of SAR and comparable with the previously available TAA CFC formulation. There was a dose response to TAA, with doses as low as 7 micrograms per nostril once daily producing statistically significant improvement in rhinitis symptoms. PMID: 23562198 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - March 1, 2013 Category: ENT & OMF Authors: Schenkel E, Newman KB Tags: Am J Rhinol Allergy Source Type: research

Can patients with common variable immunodeficiency have allergic rhinitis?
CONCLUSION: In CVID patients, chronic rhinitis may be allergic, because many have personal and family histories suggestive of atopy. However, in this study, allergy was confirmed by specific IgE detection in only 5.6% of cases. CVID patients with a history suggestive of AR commonly present negative results on traditional testing, so additional experiments may be necessary. One suggestion for the investigation of AR in CVID patients would be nasal provocation with the most prevalent allergens. PMID: 23562193 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - March 1, 2013 Category: ENT & OMF Authors: Agondi RC, Barros MT, Kokron CM, Cohon A, Oliveira AK, Kalil J, Giavina-Bianchi P Tags: Am J Rhinol Allergy Source Type: research

Perennial is more effective than preseasonal subcutaneous immunotherapy in the treatment of seasonal allergic rhinoconjunctivitis.
CONCLUSION: PIT was more effective than PSIT in the treatment of rhinoconjunctivitis in patients allergic to grass and rye pollens.Clinicaltrials.gov registration number NCT01555736. PMID: 23636036 [PubMed - as supplied by publisher]
Source: American Journal of Rhinology and Allergy - April 29, 2013 Category: ENT & OMF Authors: Tworek D, Bochenska-Marciniak M, Kuprys-Lipinska I, Kupczyk M, Kuna P Tags: Am J Rhinol Allergy Source Type: research

Chapter 17: Immunomodulation of allergic sinonasal disease.
Abstract IgE hypersensitivity is important to the pathogenesis of allergic diseases and the development and persistence of airway inflammation. Allergic immunomodulation encompasses various therapies that attempt to suppress or modify the immune mechanisms responsible for IgE-mediated disease. These include allergy immunotherapy (AIT) in the forms of subcutaneous immunotherapy (SCIT) and sublingual immunotherapy (SLIT), as well as the emergence of biological agents, such as anti-IgE, for allergic respiratory disease. Clinical evidence strongly supports the efficacy and safety of AIT for the treatment of allergic r...
Source: American Journal of Rhinology and Allergy - May 1, 2013 Category: ENT & OMF Authors: Settipane RA, Peters AT, Borish L Tags: Am J Rhinol Allergy Source Type: research