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Specialty: Infectious Diseases

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Total 742 results found since Jan 2013.

Rutgers gets up to $26 million grant to lead development of new antibiotics
(Rutgers University) The National Institute of Allergy and Infectious Diseases of the National Institutes of Health has selected infectious disease expert David Perlin, executive director of the Public Health Research Institute at Rutgers New Jersey Medical School, to lead a major research effort aimed at developing new forms of antibiotics to regain the upper hand over deadly bacteria that have become resistant to current treatments.
Source: EurekAlert! - Infectious and Emerging Diseases - April 25, 2014 Category: Infectious Diseases Source Type: news

“Drugs That Fight HIV-1” Brochure Recently Updated
The National Institute of Allergy and Infectious Diseases (NIAID) recently updated the “Drugs That Fight HIV-1” brochure, which features images of FDA-approved antiretroviral medications, grouped by drug class and identified by both generic and brand names. The brochure is available in both English and Spanish. It can be a helpful tool for health care professionals to use when discussing HIV treatment with patients. The brochure can be found in the HIV/AIDS Images section of Health Topics on our website. Contact our health information specialists by phone (1-800-448-0440) or e-mail (ContactUs@aidsinfo.nih...
Source: AIDSinfo At-a-Glance: Offering Information on HIV/AIDS Treatment, Prevention, and Research, A Service of the U.S. Department of Health and Human Services (DHHS) - April 25, 2014 Category: Infectious Diseases Source Type: news

UTMB awarded $4.4M to develop universal flu vaccine
(University of Texas Medical Branch at Galveston) UTMB researchers are working to create a universal flu vaccine -- one that could eliminate the need for an annual flu shot. Thanks to a $4.4 million grant from the National Institute of Allergy and Infectious Diseases, UTMB researchers and biotechnology company Etubics Corporation plan to construct, produce and test a vaccine containing various antigens of the A and B strains of influenza.
Source: EurekAlert! - Infectious and Emerging Diseases - May 7, 2014 Category: Infectious Diseases Source Type: news

Malaria severity not determined solely by parasite levels in blood
(NIH/National Institute of Allergy and Infectious Diseases) Although malaria kills some 600,000 African children each year, most cases of the mosquito-borne parasitic disease in children are mild. Repeated infection does generate some immunity, and episodes of severe malaria are unusual once a child reaches age 5. However, the relative contributions of such factors as the level of malaria-causing parasites in a person's blood -- parasite density -- to disease severity and to development of protective immunity are not well understood.
Source: EurekAlert! - Infectious and Emerging Diseases - May 7, 2014 Category: Infectious Diseases Source Type: news

Recent Ebola outbreak highlights need for better global response
(NIH/National Institute of Allergy and Infectious Diseases) In an invited perspective article on the Ebola outbreak under way in West Africa, Heinz Feldmann, M.D., Ph.D., of the National Institutes of Health emphasizes the need for scientists to make their data available to colleagues in real-time to improve the public health response to outbreaks. He cites past responses to influenza and SARS (severe acute respiratory syndrome) outbreaks as successful examples of global information sharing.
Source: EurekAlert! - Infectious and Emerging Diseases - May 7, 2014 Category: Infectious Diseases Source Type: news

UTMB awarded $4.4 million to develop universal flu vaccine
(University of Texas Medical Branch at Galveston) UTMB researchers are working to create a universal flu vaccine -- one that could eliminate the need for an annual flu shot. Thanks to a $4.4 million grant from the National Institute of Allergy and Infectious Diseases, UTMB researchers and biotechnology company Etubics Corporation plan to construct, produce and test a vaccine containing various antigens of the A and B strains of influenza.
Source: EurekAlert! - Infectious and Emerging Diseases - May 7, 2014 Category: Infectious Diseases Source Type: news

Screen of existing drugs finds compounds active against MERS coronavirus
(NIH/National Institute of Allergy and Infectious Diseases) Clinicians treating patients suffering from Middle East respiratory syndrome (MERS) currently have no drugs specifically targeted to the MERS coronavirus (MERS-CoV), a virus first detected in humans in 2012. To address the urgent need for therapies, researchers supported by the National Institutes of Health screened a set of 290 compounds already approved by the US Food and Drug Administration or far advanced in clinical development for other indications to determine if any might also show potential for working against MERS-CoV.
Source: EurekAlert! - Infectious and Emerging Diseases - May 20, 2014 Category: Infectious Diseases Source Type: news

Scientists identify potential vaccine candidate for pediatric malaria
(NIH/National Institute of Allergy and Infectious Diseases) Researchers have identified a substance, or antigen, that generates antibodies that can hinder the ability of malaria parasites to multiply, which may protect against severe malaria infection. The antigen, known as PfSEA-1, was associated with reduced parasite levels among children and adults in malaria-endemic areas.
Source: EurekAlert! - Infectious and Emerging Diseases - May 22, 2014 Category: Infectious Diseases Source Type: news

Scientists uncover features of antibody-producing cells in people infected with HIV
(NIH/National Institute of Allergy and Infectious Diseases) By analyzing the blood of almost 100 treated and untreated HIV-infected volunteers, a team of scientists has identified previously unknown characteristics of B cells in the context of HIV infection. B cells are the immune system cells that make antibodies to HIV and other pathogens. The findings augment the current understanding of how HIV disease develops and have implications for the timing of treatment.
Source: EurekAlert! - Infectious and Emerging Diseases - June 2, 2014 Category: Infectious Diseases Source Type: news

Grant to entomologist will advance research on African malaria mosquito
(University of California - Riverside) Bradley White, an entomologist at the University of California, Riverside, has received a five-year grant exceeding $1.8 million from the National Institute of Allergy and Infectious Diseases. The grant will allow his lab to produce fine-scale recombination rate maps for the African malaria mosquito, Anopheles gambiae. At 31, White is one of the youngest NIH R01 principal investigators in the country (well less than 1 percent of NIH principal investigators are 31 or younger).
Source: EurekAlert! - Infectious and Emerging Diseases - June 12, 2014 Category: Infectious Diseases Source Type: news

Vaccine made from complex of two malaria proteins protects mice from lethal infection
(NIH/National Institute of Allergy and Infectious Diseases) An experimental vaccine designed to spur production of antibodies against a key malaria parasite protein, AMA1, was developed more than decade ago by scientists from NIAID, part of NIH. It showed promise in test-tube and animal experiments and in early-stage clinical trials, but returned disappointing results in recent human trials conducted in malaria-endemic countries.
Source: EurekAlert! - Infectious and Emerging Diseases - June 23, 2014 Category: Infectious Diseases Source Type: news

Army leads collaborative effort to establish standards for sequencing viral genomes
(US Army Medical Research Institute of Infectious Diseases) Scientists at the US Army Medical Research Institute of Infectious Diseases have proposed a set of standards aimed at developing a common 'language' among investigators working to sequence viral genomes and characterize viral stocks. The standards, published in the journal mBio, resulted from collaborations with the Broad Institute, the J. Craig Venter Institute, Los Alamos National Laboratory, the National Institute of Allergy and Infectious Diseases, the University of Maryland and Johns Hopkins University, among others.
Source: EurekAlert! - Infectious and Emerging Diseases - June 25, 2014 Category: Infectious Diseases Source Type: news

NIH scientists establish proof-of-concept for host-directed tuberculosis therapy
(NIH/National Institute of Allergy and Infectious Diseases) In a new study published in Nature, scientists describe a new type of tuberculosis treatment that involves manipulating the body's response to TB bacteria rather than targeting the bacteria themselves, a concept called host-directed therapy.
Source: EurekAlert! - Infectious and Emerging Diseases - June 26, 2014 Category: Infectious Diseases Source Type: news

'Mississippi Baby' now has detectable HIV, researchers find
(NIH/National Institute of Allergy and Infectious Diseases) The child known as the 'Mississippi baby' -- an infant seemingly cured of HIV that was reported as a case study of a prolonged remission of HIV infection in the New England Journal of Medicine last fall -- now has detectable levels of HIV after more than two years of not taking antiretroviral therapy without evidence of virus, according to the pediatric HIV specialist and researchers involved in the case.
Source: EurekAlert! - Infectious and Emerging Diseases - July 10, 2014 Category: Infectious Diseases Source Type: news

Opisthorchis felineus liver fluke invasion is an environmental factor modifying genetic risk of atopic bronchial asthma.
Abstract According to epidemiological observations, Opisthorchis felineus liver fluke invasion is negatively associated with the development and severity of allergic diseases in endemic regions of Russia. We hypothesized that the invasion is an important factor in gene-environmental interactions (GEI) underlying allergy. To prove this, we tested 10 single nucleotide polymorphisms of immune response modifying genes in 428 individuals stratified by atopic bronchial asthma presence and O. felineus invasion. Using regression models, a statistically significant interaction between the rs6737848 polymorphism of SOCS5 ge...
Source: Acta Tropica - July 10, 2014 Category: Infectious Diseases Authors: Saltykova IV, Ogorodova LM, Bragina EY, Puzyrev VP, Freidin MB Tags: Acta Trop Source Type: research