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Procedure: Laryngoscopy

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Total 350 results found since Jan 2013.

Patterns of olfactory impairment reflect underlying disease etiology
ConclusionThis is the first study to comprehensively show that patterns of olfactory impairment reflect underlying disease etiology. We suggest that multicomponent olfactory testing should be performed, especially if there is diagnostic uncertainty. However, to clearly separate different patterns of olfactory loss to the various causes at an individual level, more work is needed. Level of Evidence4. Laryngoscope, 2016
Source: The Laryngoscope - August 23, 2016 Category: ENT & OMF Authors: Katherine L. Whitcroft, Mandy Cuevas, Antje Haehner, Thomas Hummel Tags: Allergy/Rhinology Source Type: research

Imaging follow ‐up study of acute rhinosinusitis
ConclusionsParanasal mucosal abnormalities and occlusion of the OMC do not develop gradually during ARS, but are present when symptoms begin and remain fairly constant in most patients both with and without bacterial ARS. This indicates that the spread of the disease process to the paranasal sinuses and obstruction of the OMC may not be etiological factors in the development of bacterial ARS. Level of Evidence4 Laryngoscope, 126:1965–1970, 2016
Source: The Laryngoscope - January 3, 2016 Category: ENT & OMF Authors: Timo J. Autio, Timo Koskenkorva, Mervi N ärkiö, Tuomo K. Leino, Petri Koivunen, Olli‐Pekka Alho Tags: Allergy/Rhinology Source Type: research

Design and rationale of a prospective, multi ‐institutional registry for patients with sinonasal malignancy
ConclusionThis prospective, multi‐institutional registry will provide novel oncological and QoL outcomes on patients with sinonasal malignancy to inform management decisions and disease prognostication. The application of cloud‐based computing facilitates secure multi‐institutional collaboration and may serve as a model for future registry development for the study of rare diseases in otolaryngology. Level of Evidence2C Laryngoscope, 126:1977–1980, 2016
Source: The Laryngoscope - June 9, 2016 Category: ENT & OMF Authors: Daniel M. Beswick, F. Christopher Holsinger, Michael J. Kaplan, Nancy J. Fischbein, Wendy Hara, A. Dimitrios Colevas, Quynh ‐Thu Le, Gerald J. Berry, Peter H. Hwang Tags: Allergy/Rhinology Source Type: research

Predicting revision sinus surgery in allergic fungal and eosinophilic mucin chronic rhinosinusitis
ConclusionThe presence of eosinophilic mucin was significantly associated a higher rate of revision surgery. Level of Evidence4. Laryngoscope, 2016
Source: The Laryngoscope - August 30, 2016 Category: ENT & OMF Authors: Ramzi T. Younis, Jamal Ahmed Tags: Allergy/Rhinology Source Type: research

Secreted P ‐glycoprotein is a noninvasive biomarker of chronic rhinosinusitis
ConclusionP‐gp secretion levels are significantly elevated in patients with CRS. High P‐gp secretion is associated with a higher incidence of CRSwNP and confers worse subjective and objective measures of disease severity. The presence of elevated P‐gp secretion may therefore represent a novel noninvasive biomarker of CRS and could be used to predict patients who may benefit from P‐gp inhibitory therapeutic strategies. Level of EvidenceN/A. Laryngoscope, 2016
Source: The Laryngoscope - August 30, 2016 Category: ENT & OMF Authors: Angela L. Nocera, Ana T. Meurer, Marcel M. Miyake, Peter M. Sadow, Xue Han, Benjamin S. Bleier Tags: Allergy/Rhinology Source Type: research

Endoscopic Denker's approach for resection of lesions involving the anteroinferior maxillary sinus and infratemporal fossa
Source: The Laryngoscope - September 18, 2016 Category: ENT & OMF Authors: Jivianne T. Lee, Jeffrey D. Suh, Ricardo L. Carrau, Michael W. Chu, Alexander G. Chiu Tags: Allergy/Rhinology Source Type: research

The genetics of the bitter taste receptor T2R38 in upper airway innate immunity and implications for chronic rhinosinusitis
ConclusionTaste receptors are emerging as critical components of early‐phase respiratory innate immunity, detecting molecules used by microbes to communicate and stimulating localized host defenses. Genetic polymorphisms are very common within the taste receptors, and recent linkage studies have demonstrated associations of taste receptor genetics with CRS. Lastly, ciliogenesis, which is often impacted in CRS, is critical for the functional expression of T2R38. Level of EvidenceN/A. Laryngoscope, 2016
Source: The Laryngoscope - September 21, 2016 Category: ENT & OMF Authors: Noam A. Cohen Tags: Allergy/Rhinology Source Type: research

Balloon dilation of sinus ostia in the Department of Defense: Diagnoses, actual indications, and outcomes
ConclusionsBalloon dilation of sinus ostia has an expanding role in treating sinus disease. In the studied population, BCD is often utilized for alternate indications for which there is currently no evidence of efficacy. Future studies are needed to evaluate the efficacy of this technology in treating these alternate indications. Level of Evidence4. Laryngoscope, 2016
Source: The Laryngoscope - September 23, 2016 Category: ENT & OMF Authors: Adrienne M. Laury, Sarah N. Bowe, Joshua Stramiello, Kevin C. McMains Tags: Allergy/Rhinology Source Type: research

Rapid hemostasis in a sheep model using particles that propel thrombin and tranexamic acid
ConclusionsSPTT significantly reduced bleeding time in a sheep model of surgical sinus bleeding and successfully stopped bleeding following catastrophic carotid artery injury, with no adverse events observed. Level of EvidenceNA Laryngoscope, 2016
Source: The Laryngoscope - October 31, 2016 Category: ENT & OMF Authors: James R. Baylis, Andres Finkelstein ‐Kulka, Luis Macias‐Valle, Jamil Manji, Michael Lee, Elina Levchenko, Christopher Okpaleke, Salahuddin Al‐Salihi, Amin Javer, Christian J. Kastrup Tags: Allergy/Rhinology Source Type: research

Prevalence of polyp recurrence after endoscopic sinus surgery for chronic rhinosinusitis with nasal polyposis
ConclusionsPolyp recurrence is common after ESS with control of polyps up to 18 months found in approximately 60% to 70% of patients. Investigation into both surgical and medical management strategies is warranted to improve upon the observed prevalence of recurrence. Level of Evidence2c. Laryngoscope, 2016
Source: The Laryngoscope - November 11, 2016 Category: ENT & OMF Authors: Adam S. DeConde, Jess C. Mace, Joshua M. Levy, Luke Rudmik, Jeremiah A. Alt, Timothy L. Smith Tags: Allergy/Rhinology Source Type: research

The prevalence of olfactory dysfunction in chronic rhinosinusitis
ConclusionsIn CRS populations, a significant percentage of patients experience olfactory dysfunction, and mean olfactory scores are within the dysosmic range.Laryngoscope, 2016
Source: The Laryngoscope - November 21, 2016 Category: ENT & OMF Authors: Preeti Kohli, Akash N. Naik, E. Emily Harruff, Shaun A. Nguyen, Rodney J. Schlosser, Zachary M. Soler Tags: Allergy/Rhinology Source Type: research

Microarray analysis of the genes associated with osteitis in chronic rhinosinusitis
ConclusionsThese findings will add a new perspective to our current understanding of the recalcitrant CRS. Level of EvidenceNA Laryngoscope, 2016
Source: The Laryngoscope - November 25, 2016 Category: ENT & OMF Authors: Ceren G ünel, Benjamin S. Bleier, Gökay Bozkurt, Nuket Eliyatkin Tags: Allergy/Rhinology Source Type: research

Antibiotics in eosinophilic chronic rhinosinusitis: Rethinking maximal antimicrobial medical therapy
ConclusionsThe use of antibiotics without independent anti‐inflammatory properties have limited efficacy in patients with eCRS. The concept of maximal medical therapy using antibiotics must continue to evolve in the setting of new evidence for inflammatory subtypes of CRS. Level of Evidence2b. Laryngoscope, 2016
Source: The Laryngoscope - November 25, 2016 Category: ENT & OMF Authors: Ceren G ünel, Benjamin S. Bleier, Ibrahim Meteoglu Tags: Allergy/Rhinology Source Type: research

Is nonabsorbable nasal packing after septoplasty essential? A meta ‐analysis
ConclusionsNonabsorbable nasal packing is no more effective than treatments without packing after septoplasty. Septal splints and transseptal sutures reduce postoperative pain, headache, and synechia. Level of EvidenceNA Laryngoscope, 2016
Source: The Laryngoscope - November 29, 2016 Category: ENT & OMF Authors: Jong Seung Kim, Sam Hyun Kwon Tags: Allergy/Rhinology Source Type: research

Fabrication and validation of a low ‐cost, medium‐fidelity silicone injection molded endoscopic sinus surgery simulation model
ConclusionsSimulation models have proven efficacy in endoscopic skill and procedural training. The group developed a novel low‐cost, medium‐fidelity sinus training model utilizing three‐dimensional modeling and printing. Testing of this model revealed high ratings for both face and construct validity for a range of endoscopic procedures. Strong interest in using this model for resident training was unanimous among all survey participants. Level of EvidenceNA Laryngoscope, 2016
Source: The Laryngoscope - December 20, 2016 Category: ENT & OMF Authors: Daniel R. Chang, Ryan P. Lin, Sarah Bowe, Leon Bunegin, Erik K. Weitzel, Kevin C. McMains, Thomas Willson, Philip G. Chen Tags: Allergy/Rhinology Source Type: research