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Potential of targeting host cell calcium dynamics to curtail SARS-CoV-2 infection and COVID-19 pathogenesis
Cell Calcium. 2022 Aug 11;106:102637. doi: 10.1016/j.ceca.2022.102637. Online ahead of print.ABSTRACTSevere Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) infection and associated coronavirus disease 2019 (COVID-19) has severely impacted human well-being. Although vaccination programs have helped in reducing the severity of the disease, drug regimens for clinical management of COVID-19 are not well recognized yet. It is therefore important to identify and characterize the molecular pathways that could be therapeutically targeted to halt SARS-CoV-2 infection and COVID-19 pathogenesis. SARS-CoV-2 hijacks host cell mol...
Source: Cell Research - August 20, 2022 Category: Cytology Authors: Farina Sultan Kriti Ahuja Rajender K Motiani Source Type: research

Formulation Optimization and Evaluation of Nanocochleate Gel of Famciclovir for the Treatment of Herpes Zoster
CONCLUSION: A novel nanocochleate gel of Famciclovir was successfully developed for the treatment of infections associated with Herpes Zoster with sustained release action.PMID:35733311 | DOI:10.2174/1872210516666220622115553
Source: Herpes - June 23, 2022 Category: Infectious Diseases Authors: Rahul Sharma Ashwini Deshpande Abhishek Kanugo Source Type: research