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Specialty: Drugs & Pharmacology
Infectious Disease: Adenoviruses
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Total 33 results found since Jan 2013.
Protein kinase CK2 α catalytic subunit ameliorates diabetic renal inflammatory fibrosis via NF-κB signaling pathway.
This study indicates the essential role of CK2α in regulating the diabetic renal pathological process of inflammatory fibrosis via NF-κB pathway, and inhibition of CK2α may serve as a promising therapeutic strategy for diabetic nephropathy.
PMID: 28237649 [PubMed - as supplied by publisher]
Source: Biochemical Pharmacology - February 21, 2017 Category: Drugs & Pharmacology Authors: Huang J, Chen Z, Li J, Chen Q, Li J, Gong W, Huang J, Liu P, Huang H Tags: Biochem Pharmacol Source Type: research
Argonaute 2 promotes angiogenesis via the PTEN/VEGF signaling pathway in human hepatocellular carcinoma.
CONCLUSION: A direct relationship exists between the miRNA processing machinery AGO2 and HCC angiogenesis that is mediated by the AGO2/PTEN/VEGF signaling pathway. The results suggest the high value of Ago2 knockdown in anti-angiogenesis therapy for HCC.
PMID: 25937637 [PubMed - as supplied by publisher]
Source: Acta Pharmacologica Sinica - May 4, 2015 Category: Drugs & Pharmacology Authors: Ye ZL, Huang Y, Li LF, Zhu HL, Gao HX, Liu H, Lv SQ, Xu ZH, Zheng LN, Liu T, Zhang JL, Jin HJ, Qian QJ Tags: Acta Pharmacol Sin Source Type: research
The Role of Caveolin-1 and Syndecan-4 in the Internalization of PEGylated PAMAM Dendrimer Polyplexes into Myoblast and Hepatic Cells.
This study gives a clue how to take strategies by up- or down-regulation of the expressions of Syndecan-4 and Caveolin-1 to improve in vivo gene delivery efficiency of the PEG-PAMAM dendrimers in clinical transgenic therapy.
PMID: 25083608 [PubMed - as supplied by publisher]
Source: European Journal of Pharmaceutics and Biopharmaceutics - July 29, 2014 Category: Drugs & Pharmacology Authors: Shen W, van Dongen MA, Han Y, Yu M, Li Y, Liu G, BanaszakHoll MM, Qi R Tags: Eur J Pharm Biopharm Source Type: research
