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Researchers to Study Why COVID-19 Strikes Asthma Sufferers Less Severely Than Others
A University of Arizona Health Sciences-led research team received $7.16 million in federal funding to study how to better control severe asthma and determine why sufferers are less likely to contract COVID-19, influenza and rhinovirus. Today University of Arizona Health Scienceswomen_blowing_nose-948301830-hero-web.jpgHealthCollege of Medicine - TucsonExpertsExplorationResearchAn investigation into why asthma sufferers are less likely to contract COVID-19 is one of several aims for research funded through a $7.16 million National Institutes of Health cooperative agreement with the  Asthma and Airway Disease Research ...
Source: The University of Arizona: Health - December 9, 2021 Category: Universities & Medical Training Authors: mittank Source Type: research

Study unravels antibiotic resistance in MRSA ‘superbug’ infections
FINDINGSResearchers applied a new approach pioneered at UCLA to predict whichmethicillin-resistant Staphylococcus aureus, or MRSA,infections willfail to respond toantibiotic treatment. By focusing on epigenetics — changes to gene expression that can’t be detected by standard DNA sequencing — the study examined how the immune system recognizes dangerous superbugs and works with antibiotics to clear them.BACKGROUNDThe Staphylococcus aureus bacterium can  live harmlessly on a person’s skin and in their nose, occasionally causing mild infections that can be treated with standard antibiotics. When itentersthe bloodstre...
Source: UCLA Newsroom: Health Sciences - March 3, 2021 Category: Universities & Medical Training Source Type: news

First childhood flu helps explain why virus hits some people harder than others
Why are some people better able to fight off the flu than others? Part of the answer, according to a new study, is related to the first flu strain we encounter in childhood.Scientists from UCLA and the University of Arizona have found that people ’s ability to fight off the flu virus is determined not only by the subtypes of flu they have had throughout their lives, but also by the sequence in which they are been infected by the viruses. Their study is published in the open-access journal PLoS Pathogens.The research offers an explanation for why some people fare much worse than others when infected with the same strain...
Source: UCLA Newsroom: Health Sciences - February 4, 2020 Category: Universities & Medical Training Source Type: news

Association of Breastfeeding Duration with Susceptibility to Allergy, Influenza, and Methylation Status of TLR1 Gene.
Conclusions: The findings demonstrate the significance of increased breastfeeding duration for improved health outcomes at the gene level. PMID: 31454983 [PubMed - in process]
Source: Medicina (Kaunas) - August 25, 2019 Category: Universities & Medical Training Authors: Hatmal MM, Issa NN, Alshaer W, Al-Ameer HJ, Abuyaman O, Tayyem R, Hijjawi NS Tags: Medicina (Kaunas) Source Type: research

Community-based HIV prevention can boost testing, help reduce new infections
Communities in Africa and Thailand that worked together on HIV-prevention efforts saw not only a rise in HIV screening but a drop in new infections, according to a new study in the peer-reviewed journal The Lancet Global Health.   The U.S. National Institute of Mental Health's Project Accept — a trial conducted by the HIV Prevention Trials Network to test a combination of social, behavioral and structural HIV-prevention interventions — demonstrated that a series of community efforts boosted the number of people tested for HIV and resulted in a 14 percent reduction in new HIV infections, compared with control communi...
Source: UCLA Newsroom: Health Sciences - April 18, 2014 Category: Universities & Medical Training Source Type: news

Community-based HIV-prevention efforts can boost testing, help reduce new infections
In Africa and Thailand, communities that worked together on HIV-prevention efforts saw not only a rise in HIV screening but a drop in new infections, according to a new study presented this week at the Conference on Retroviruses and Opportunistic Infections in Atlanta.   The U.S. National Institute of Mental Health's Project Accept — a trial conducted by the HIV Prevention Trials Network to test a combination of social, behavioral and structural HIV-prevention interventions — demonstrated that a series of community efforts was able to boost the number of people tested for...
Source: UCLA Newsroom: Health Sciences - March 5, 2013 Category: Universities & Medical Training Source Type: news

Newly identified natural protein blocks HIV, other deadly viruses
A team of UCLA-led researchers has identified a protein with broad virus-fighting properties that potentially could be used as a weapon against deadly human pathogenic viruses such as HIV, Ebola, Rift Valley Fever, Nipah and others designated "priority pathogens" for national biosecurity purposes by the National Institute of Allergy and Infectious Disease.   In a study published in the January issue of the journal Immunity, the researchers describe the novel antiviral property of the protein, cholesterol-25-hydroxylase (CH25H), an enzyme that converts cholesterol to an oxysterol called 25-hydroxycholesterol (25HC), wh...
Source: UCLA Newsroom: Health Sciences - February 11, 2013 Category: Universities & Medical Training Source Type: news