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How do bats live with so many viruses? New bat stem cells hint at an answer
Compared with other mammals, bats are notorious for hosting more viruses that are dangerous to people but not themselves. It’s an oddity that’s drawn renewed attention since COVID-19 broke out in humans—many scientists suspect the coronavirus SARS-CoV-2 leaped from bats into people, directly or via an intermediate host. Seeking to create large quantities of bat tissue to help study why the flying animals are so virus-friendly, a research team now reports it has transformed adult bat cells into versatile stem cells that can be coaxed to form many kinds of tissue . The advance, described today in Cell ...
Source: Science of Aging Knowledge Environment - February 21, 2023 Category: Geriatrics Source Type: research

NIDCR's Spring 2021 E-Newsletter
Having trouble viewing this email? View it as a Web page. NIDCR's Spring 2021 E-Newsletter In this issue: NIDCR News Funding Opportunities & Related Notices NIH/HHS News Subscribe to NICDR News Science Advances   Grantee News   NIDCR News NIDCR & NIH Stand Against Structural Racism NIDCR Director Rena D’Souza, DDS, MS, PhD, said in a statement that there is no place for structural racism in biomedical research, echoing remarks from NIH Director Francis Collins, MD, PhD, in his announcement of a new NIH initiative—called UNIT...
Source: NIDCR Science News - April 7, 2021 Category: Dentistry Source Type: news

UCLA researchers study genetics ’ role in COVID-19 susceptibility, severity
“One of the most troubling things about COVID-19 is that we have a limited ability to predict how sick a specific individual will get,” said Dr. Daniel Geschwind.Geschwind is the MacDonald Distinguished Professor in Human Genetics at theDavid Geffen School of Medicine at UCLA and a member of theEli and Edythe Broad Center of  Regenerative Medicine and Stem Cell Research at UCLA. And he ’s part of a team of UCLA scientists conducting research to learn why certain people get sick from the virus that causes COVID-19 — and why others don’t.Millions of people around the world have been infected with SARS-CoV-2, the v...
Source: UCLA Newsroom: Health Sciences - October 26, 2020 Category: Universities & Medical Training Source Type: news

Development of passive immunity against SARS-CoV-2 for management of immunodeficient patients —a perspective
The recent coronavirus disease 2019 (COVID-19) pandemic raises serious concerns about potential prophylaxis and therapy in a naive population, particularly in patients with primary or secondary immunodeficiencies. The former mainly includes patients with defects in T-cell –mediated immunity and, to a lesser extent, those with antibody deficiencies and immune dysregulation. The latter includes patients undergoing therapy with immunosuppressive drugs, such as stem cell transplanted patients. In addition, patients with B-cell malignancies and autoimmune disorders trea ted with selected forms of targeted therapy (such as ant...
Source: Journal of Allergy and Clinical Immunology - May 11, 2020 Category: Allergy & Immunology Authors: Lennart Hammarstr öm, Hassan Abolhassani, Fausto Baldanti, Harold Marcotte, Qiang Pan-Hammarström Tags: Editorial Source Type: research