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In vitro antibacterial activity and physicochemical properties of a crude methanol extract of the larvae of the blow fly Lucilia cuprina
Abstract The emergence of multidrug‐resistant bacterial strains has prompted the reintroduction of maggot therapy in the treatment of chronic, infected wounds. Many previous studies have demonstrated the potent antibacterial activity of larval excretions/secretions of the blowfly Lucilia sericata (Meigen) (Diptera:Calliphoridae) against bacteria. However, the antibacterial activity of its sibling species, Lucilia cuprina (Wiedemann) (Diptera:Calliphoridae) against a wide range of pathogenic bacteria has never been determined. The aim of this study was to develop a new procedure to produce whole body extract of larvae of ...
Source: Medical and Veterinary Entomology - May 8, 2013 Category: Veterinary Research Authors: C. H. TEH, W. A. NAZNI, H. L. LEE, A. FAIRUZ, S. B. TAN, M. SOFIAN‐AZIRUN Tags: Original Article Source Type: research

Use of maggot therapy for treating a diabetic foot ulcer colonized by multidrug resistant bacteria in Brazil.
This study reports the efficacy of maggot therapy in the treatment of diabetic foot ulcer infected with multidrug resistant microorganisms. A 74 year old female patient with diabetes for over 30 years, was treated with maggot therapy using larvae of Chrysomya megacephala. The microbiological samples were collected to evaluate aetiology of the infection. The therapy done for 43 days resulted in a reduction of necrosis and the ulcer's retraction of 0.7 cm [2] in area. Analysis of the bacteriological swabs revealed the presence of Escherichia coli, Klebsiella pneumoniae and Pseudomonas aeruginosa. Further studies need to be d...
Source: The Indian Journal of Medical Research - March 1, 2015 Category: Biomedical Science Authors: Pinheiro MA, Ferraz JB, Junior MA, Moura AD, da Costa ME, Costa FJ, Neto VF, Neto RM, Gama RA Tags: Indian J Med Res Source Type: research

Acceleration of cutaneous wound healing by Lucilia sericata maggots in diabetic Wistar rats
Trop Biomed. 2021 Mar 1;38(1):86-93. doi: 10.47665/tb.38.1.015.ABSTRACTThe study was aimed to evaluate the effectiveness of maggot therapy in healing of cutaneous infected wound in streptozotocin (STZ) induced diabetic Wistar rat. For live maggots, the sterilized eggs of Lucilia sericata were obtained from colonies established in laboratory. Diabetes model was established in 48 male Wister rat by intra-peritoneal injection of STZ at the dose of 60 mg/kg body-weight. Cutaneous wounds exposed with mixed colonies of bacteria like Staphylococcus aureus, E. coli and Pseudomonas aeruginosa were prepared in all rat. The animals e...
Source: Tropical Biomedicine - April 2, 2021 Category: Tropical Medicine Authors: S Borkataki R Katoch P Goswami A Bhat D Chakraborty Source Type: research

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