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Source: The Journal of Allergy and Clinical Immunology: In Practice
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Clinical Management of Seafood Allergy
Publication date: January 2020Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 8, Issue 1Author(s): Carla M. Davis, Ruchi S. Gupta, Ozge N. Aktas, Veronica Diaz, Sandip D. Kamath, Andreas L. LopataSeafood plays an important role in human nutrition and health. A good patient workup and sensitive diagnostic analysis of IgE antibody reactivity can distinguish between a true seafood allergy and other adverse reactions generated by toxins or parasites contaminating ingested seafood. The 2 most important seafood groupings include the fish and shellfish. Shellfish, in the context of seafood consumption,...
Source: The Journal of Allergy and Clinical Immunology: In Practice - January 16, 2020 Category: Allergy & Immunology Source Type: research
Prevalence and Predictors of Food Allergy in Canada: A Focus on Vulnerable Populations
Conclusion Analysis of our data suggests that individuals of low education and new Canadians self-report fewer allergies, which may be due to genetics, environment, lack of appropriate health care, or lack of awareness of allergies, which reduces self-report.
Source: The Journal of Allergy and Clinical Immunology: In Practice - January 7, 2015 Category: Allergy & Immunology Source Type: research
Improving the Effectiveness of Penicillin Allergy De-labeling
Conclusions Penicillin SPT/IDT/OC safely de-labels penicillin-allergic patients and identifies selective beta-lactam allergies; however, incomplete adherence to ALM recommendations impairs effectiveness. Infrequent SPT/IDT+ and absent OC reactions in patients with NIM reactions suggest OC alone to be a safe and cost-effective de-labeling strategy that could improve the coverage of penicillin allergy de-labeling in lower risk populations.
Source: The Journal of Allergy and Clinical Immunology: In Practice - January 14, 2015 Category: Allergy & Immunology Source Type: research
House Dust Mite Respiratory Allergy: An Overview of Current Therapeutic Strategies
Publication date: Available online 3 September 2015 Source:The Journal of Allergy and Clinical Immunology: In Practice Author(s): Moisés A. Calderón, Jörg Kleine-Tebbe, Allan Linneberg, Frédéric De Blay, Dolores Hernandez Fernandez de Rojas, Johann Christian Virchow, Pascal Demoly Although house dust mite (HDM) allergy is a major cause of respiratory allergic disease, specific diagnosis and effective treatment both present unresolved challenges. Guidelines for the treatment of allergic rhinitis and asthma are well supported in the literature, but specific evidence on the efficacy of pharmacotherapy treatmen...
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 3, 2015 Category: Allergy & Immunology Source Type: research
Prospects for Prevention of Food Allergy
Publication date: Available online 2 January 2016 Source:The Journal of Allergy and Clinical Immunology: In Practice Author(s): Katrina J. Allen, Jennifer J. Koplin A rise in both prevalence and public awareness of food allergy in developed countries means that clinicians and researchers are frequently asked to explain reasons for the increase in food allergy, and families are eager to know whether they can take steps to prevent food allergy in their children. In this review, we outline leading theories on risk factors for early life food allergy. We summarize the leading hypotheses to explain the increase in food alle...
Source: The Journal of Allergy and Clinical Immunology: In Practice - March 5, 2016 Category: Allergy & Immunology Source Type: research
Racial Differences in Food Allergy Phenotype and Health Care Utilization among US Children
Conclusions FA phenotypes and health care utilization differ among children of different racial and/or ethnic backgrounds in the United States that put AA and Hispanic children at higher risks of adverse outcome than white children. These differences include coexistent atopic conditions, less well recognized food allergens, and higher rates of anaphylaxis.
Source: The Journal of Allergy and Clinical Immunology: In Practice - November 22, 2016 Category: Allergy & Immunology Source Type: research
Making the Most of In Vitro Tests to Diagnose Food Allergy
Publication date: March–April 2017 Source:The Journal of Allergy and Clinical Immunology: In Practice, Volume 5, Issue 2 Author(s): Alexandra F. Santos, Helen A. Brough Various in vitro tests assess different aspects of the underlying immune mechanism of IgE-mediated food allergy. Some can be used for diagnostic purposes; specific IgE to allergen extracts is widely available; specific IgE to allergen components is used in most specialist centers, and the basophil activation test is becoming increasingly used clinically. IgE to allergen peptides, T-cell assays, allergen-specific/total IgE ratios, and allergen-specific I...
Source: The Journal of Allergy and Clinical Immunology: In Practice - March 6, 2017 Category: Allergy & Immunology Source Type: research
The Effect of Penicillin Allergy Testing on Future Health Care Utilization: A Matched Cohort Study
Conclusions Penicillin allergy testing, primarily done in the setting of an outpatient Allergy consultation, was associated with significantly less health care utilization during 3.6+ years of follow-up and greater use of narrow-spectrum antibiotics. Penicillin allergy testing has a favorable cost-benefit ratio for the incremental cost of testing versus future health care utilization and improves antibiotic stewardship.
Source: The Journal of Allergy and Clinical Immunology: In Practice - March 31, 2017 Category: Allergy & Immunology Source Type: research
A multicenter evaluation of diagnosis and management of omega-5 gliadin allergy (also known as wheat-dependent exercise induced anaphylaxis) in 132 adults
Conclusions Omega-5 gliadin allergy is a rare wheat allergy that presents with severe anaphylaxis. The diagnosis is frequently delayed, therefore we recommend that all adult patients presenting with anaphylaxis of unclear cause should have omega-5 gliadin specific IgE tested. A gluten-free diet or avoidance of wheat based meals in combination with exercise (if the cofactor is exercise) helps to significantly decrease the risk of future allergic reactions. However, antihistamines and an epinephrine auto-injector must always be prescribed, as a third of patients continue to have allergic reactions despite dietary advice.
Source: The Journal of Allergy and Clinical Immunology: In Practice - March 2, 2018 Category: Allergy & Immunology Source Type: research
Vaccine Allergy? Skin testing and challenge at a tertiary pediatric hospital in Melbourne, Australia
ConclusionThe vast majority of children (92%) presenting with a potential IgE-mediated AEFI are able to tolerate challenge to suspect vaccine without reaction. We present our investigation protocol recommending skin testing in all children with anaphylaxis and challenge with suspect vaccine if negative testing or previous non-anaphylactic potential IgE mediated AEFI.
Source: The Journal of Allergy and Clinical Immunology: In Practice - January 23, 2019 Category: Allergy & Immunology Source Type: research
Preventing Peanut Allergy: Where Are We Now?
Publication date: February 2019Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 7, Issue 2Author(s): Helen R. Fisher, Corinne A. Keet, Gideon Lack, George du ToitPeanut allergy affects 1% to 3% of the Western world, usually begins in early childhood, is rarely outgrown, and has no currently approved treatment. The identification and application of prevention strategies is therefore essential. In 2015, the Learning Early About Peanuts study findings found that early consumption of peanut protein was effective in preventing peanut allergy in high-risk children as compared with peanut avoidance. The...
Source: The Journal of Allergy and Clinical Immunology: In Practice - February 2, 2019 Category: Allergy & Immunology Source Type: research
Identifying Low-risk Beta-Lactam allergy Patients in a UK Tertiary Centre
ConclusionWe identified a “low risk” cohort of patients where the history is of similar reliability to skin testing in predicting non-allergic status for BL allergy.
Source: The Journal of Allergy and Clinical Immunology: In Practice - March 26, 2019 Category: Allergy & Immunology Source Type: research
Patterns of North American Women Authorship in 2 Allergy/Immunology Journals: 1997-2017
ConclusionsWomen authorship has become more frequent in the Journal of Allergy and Clinical Immunology and Annals of Allergy, Asthma and Immunology. The probability of women being first authors is more likely in articles with women as last authors, implying that mentorship of women by women may encourage women to become more active in scholarship.
Source: The Journal of Allergy and Clinical Immunology: In Practice - May 3, 2019 Category: Allergy & Immunology Source Type: research
Quality of life in patients with allergic reactions to medications. Influence of a drug allergy evaluation
ConclusionHaving suffered anaphylaxis, more than one reported drug allergy or presenting a musculoskeletal disease are factors that worsen the quality of life. Quality of life improved significantly after completing a drug allergy evaluation.
Source: The Journal of Allergy and Clinical Immunology: In Practice - May 24, 2019 Category: Allergy & Immunology Source Type: research
Comparing direct challenge to penicillin skin testing for the outpatient evaluation of penicillin allergy: A randomized, controlled trial
ConclusionsIn low risk patients, DC provided a safe and effective alternative to PST in de-labeling penicillin allergy. Compared to PST, DC may also take less time, cost less money, and lead to fewer penicillin allergy evaluations with false positive results.
Source: The Journal of Allergy and Clinical Immunology: In Practice - June 4, 2019 Category: Allergy & Immunology Source Type: research
