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Source: The Journal of Allergy and Clinical Immunology: In Practice
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The Journal of Allergy and Clinical Immunology: In Practice 2017 Year in Review
Publication date: Available online 1 February 2018 Source:The Journal of Allergy and Clinical Immunology: In Practice Author(s): Michael Schatz, Scott H. Sicherer, Robert S. Zeiger An impressive number of clinically impactful studies and reviews were published in The Journal of Allergy and Clinical Immunology: In Practice in 2017. As a service to our readers, the editors provide this Year in Review article to highlight and contextualize the advances published over the past year. We include information from articles on asthma, allergic rhinitis, rhinosinusitis, immunotherapy, atopic dermatitis, contact dermatitis, food all...
Source: The Journal of Allergy and Clinical Immunology: In Practice - February 2, 2018 Category: Allergy & Immunology Source Type: research
The Health and Economic Outcomes of Peanut Allergy Management Practices
Conclusions Commonly recommended practices of pre-emptive epinephrine injection in the absence of symptoms, or universal avoidance of PAL were not cost-effective when compared with administering epinephrine upon symptom development or allowing PAL consumption.
Source: The Journal of Allergy and Clinical Immunology: In Practice - May 11, 2018 Category: Allergy & Immunology Source Type: research
Phenotypic Characterization of Eosinophilic Esophagitis in a Large Multi-Center Patient Population from the Consortium for Food Allergy Research
ConclusionsGastrointestinal eosinophilia is present in ∼10% of EoE patients; the symptom-diagnosis time gap is influenced by age, race, food allergy and atopic dermatitis; symptoms vary with race; concurrent infectious/immunological disorders and mental health disorders are common; and the level of esophageal eosinophils is comparable in patients with and without fibrostenotic features.
Source: The Journal of Allergy and Clinical Immunology: In Practice - August 1, 2018 Category: Allergy & Immunology Source Type: research
Pathways to Improved Antibiotic Allergy and Antimicrobial Stewardship Practice - The Validation of a Beta-Lactam Antibiotic Allergy Assessment Tool
Publication date: Available online 29 August 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Misha Devchand, Karen Urbancic, Sharmila Khumra, Abby Douglas, Olivia Smibert, Emma Cohen, Michael Sutherland, Elizabeth J. Phillips, Jason A. TrubianoSummaryThe validation of a beta-lactam antibiotic allergy assessment allows non-allergists to effectively phenotype patient-reported antibiotic allergies and direct them to appropriate ‘de-labeling’ stratergies.
Source: The Journal of Allergy and Clinical Immunology: In Practice - August 29, 2018 Category: Allergy & Immunology Source Type: research
Rostrum: Latex Allergy Risks Live On
Publication date: Available online 21 September 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Kim Liberatore, Kevin J. KellyReduction in the prevalence of IgE-mediated allergy to latex proteins from gloves in patients may lead to lax attention by health care personnel to avoid use of latex products in latex-allergic subjects. Recent evidence from the Pennsylvania Patient Safety Reporting System shows an alarming continuation of adverse events mostly from latex urinary catheters. We are strongly advocating that health care personnel must continue to pay close attention to avoidance of lat...
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 22, 2018 Category: Allergy & Immunology Source Type: research
The Health and Economic Outcomes of Peanut Allergy Management Practices
ConclusionsCommonly recommended practices of pre-emptive epinephrine injection in the absence of symptoms, or universal avoidance of PAL, were not cost-effective when compared with administering epinephrine on symptom development or allowing PAL consumption.
Source: The Journal of Allergy and Clinical Immunology: In Practice - November 2, 2018 Category: Allergy & Immunology Source Type: research
Latex Allergy Risks Live On
Publication date: November–December 2018Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 6, Issue 6Author(s): Kim Liberatore, Kevin J. KellyReduction in the prevalence of IgE-mediated allergy to latex proteins from gloves in patients may lead to lax attention by health care personnel to avoid use of latex products in latex-allergic subjects. Recent evidence from the Pennsylvania Patient Safety Reporting System shows an alarming continuation of adverse events mostly from latex urinary catheters. We are strongly advocating that health care personnel must continue to pay close attention to avoidan...
Source: The Journal of Allergy and Clinical Immunology: In Practice - November 2, 2018 Category: Allergy & Immunology Source Type: research
Managing Cross-Reactivity in Those with Peanut Allergy
Publication date: Available online 22 November 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Edmond S. Chan, Matthew J. Greenhawt, David M. Fleischer, Jean-Christoph CaubetAbstractPeanut is an allergenic legume that can cross-react with other plant-based foods, notably other legumes and tree nuts. Peanut allergic individuals can be both co-sensitized as well as co-allergic to such items, requiring foresight when eliciting a clinical history of reaction, in the diagnostic evaluation of such allergies, and in the counseling of patients as to food avoidances after a diagnosis is made. Legum...
Source: The Journal of Allergy and Clinical Immunology: In Practice - November 23, 2018 Category: Allergy & Immunology Source Type: research
The Journal of Allergy and Clinical Immunology: In Practice 2018 Highlights
This article provides highlights of the original research published in 2018 issues of JACI: In Practice on the subjects of anaphylaxis, asthma, dermatitis, drug allergy, eosinophilic disorders, food allergy, immune deficiency, rhinitis/upper respiratory disease, and urticaria/angioedema. Within each topic, practical aspects of diagnosis and management are emphasized. Treatments discussed include lifestyle modifications, allergen avoidance therapy, positive and negative effects of pharmacologic therapy, and various forms of immunologic and desensitization management. We hope this review will help readers consolidate and use...
Source: The Journal of Allergy and Clinical Immunology: In Practice - December 15, 2018 Category: Allergy & Immunology Source Type: research
Impact of Omalizumab on Food Allergy in Patients Treated for Asthma: A Real-Life Study
ConclusionsDuring treatment with omalizumab for severe uncontrolled asthma, the food allergen threshold increases to 8.6 times its original value. The quality of life of patients also increased, due to a better asthma control and a reduction in dietary restrictions. The cost/benefit ratio of such treatment for selected cases of food allergy remains to be evaluated.
Source: The Journal of Allergy and Clinical Immunology: In Practice - February 20, 2019 Category: Allergy & Immunology Source Type: research
Clinical and Molecular Characterization of Walnut and Pecan Allergy (NUT CRACKER Study)
ConclusionsWalnut components are helpful in diagnosing walnut allergy and in identifying patients with pecan coallergy. Competitive ELISA indicates that pecan comprises a subset of the allergenic determinants of walnut.
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 26, 2019 Category: Allergy & Immunology Source Type: research
Presentation and Management of Food Allergy in Breastfed Infants and Risks of Maternal Elimination Diets
Publication date: Available online 18 November 2019Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Puja Sood Rajani, Hayley Martin, Marion Groetch, Kirsi M. JärvinenAbstractBreastfeeding is currently recommended as the optimal source of nutrition to infants. However, there are several studies that have shown clinical IgE and non-IgE-mediated reactions to foods in exclusively breastfeeding infants, specifically to cow’s milk, egg, peanut, and fish. Literature suggests that antigenic food proteins present in human milk can be found in substantial enough amounts to elicit clinical reactions in...
Source: The Journal of Allergy and Clinical Immunology: In Practice - November 18, 2019 Category: Allergy & Immunology Source Type: research
A Multicenter retrospective study on hypersensitivity reactions to Non-Steroidal Anti-inflammatory Drugs (NSAIDs) in children: a report from the European Network on Drug Allergy (ENDA) group
ConclusionThe value of this study is that although different approaches are used around Europe to diagnose NSAIDs HS, we found that the percentage of confirmed NSAIDs HS is less than 20%. This highlights the importance of the DPT in confirming or excluding NSAIDs HS in the pediatric population.
Source: The Journal of Allergy and Clinical Immunology: In Practice - November 28, 2019 Category: Allergy & Immunology Source Type: research
Food Allergy Prevention: More Than Peanut
Publication date: January 2020Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 8, Issue 1Author(s): Michael R. Perkin, Alkis Togias, Jennifer Koplin, Scott SichererGiven an apparent increase in food allergies worldwide, the focus on prevention strategies has intensified. Following the Learning Early About Peanut study, there is now a widespread acceptance that peanut should be introduced promptly into the diet of high-risk infants. However, most food allergies are caused by triggers other than peanut and additional prevention strategies are being evaluated. The appreciation of the role of an impa...
Source: The Journal of Allergy and Clinical Immunology: In Practice - January 16, 2020 Category: Allergy & Immunology Source Type: research
Food Allergy and Eosinophilic Esophagitis: What Do We Do?
Publication date: January–February 2015 Source:The Journal of Allergy and Clinical Immunology: In Practice, Volume 3, Issue 1 Author(s): Mirna Chehade , Seema S. Aceves , Glenn T. Furuta , David M. Fleischer Eosinophilic esophagitis (EoE) is an inflammatory disease of the esophagus triggered by foods and possibly environmental allergens. Common conditions that mimic EoE include gastroesophageal reflux disease and proton pump inhibitor-responsive esophageal eosinophilia. These need to be excluded before confirming the diagnosis of EoE. Identification of food triggers for EoE using standard allergy tests remains challeng...
Source: The Journal of Allergy and Clinical Immunology: In Practice - January 7, 2015 Category: Allergy & Immunology Source Type: research
