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A prospective, randomized, placebo ‐controlled study of inferior turbinate surgery
ConclusionsThe placebo effect had a large role in the overall improvement of the severity of nasal obstruction after the inferior turbinate surgery. However, all three techniques provided a statistically significant additional reduction of the severity of nasal obstruction compared to the placebo procedure. Level of Evidence1b. Laryngoscope, 2018
Source: The Laryngoscope - February 2, 2018 Category: ENT & OMF Authors: Teemu Harju, Jura Numminen, Ilkka Kivek äs, Markus Rautiainen Tags: Allergy/Rhinology Source Type: research

Diagnostic reliability of pretreatment biopsy in malignant nasoethmoidal tumors: A retrospective study of 77 cases
ConclusionsThe risk of misdiagnosis for nasoethmoidal tumors may be high even in referral centers. Especially when clinical and radiologic findings suggest a diagnosis different from adenocarcinoma, mucosal melanoma, and olfactory neuroblastoma, obtaining abundant material under general anesthesia may reduce the risk of diagnostic error and inadequate treatment. Level of Evidence4. Laryngoscope, 2018
Source: The Laryngoscope - January 4, 2018 Category: ENT & OMF Authors: Alberto Schreiber, Vittorio Rampinelli, Marco Ferrari, Davide Mattavelli, Davide Farina, Simonetta Battocchio, Piero Nicolai Tags: Allergy/Rhinology Source Type: research

Impact of obstructive sleep apnea in transsphenoidal pituitary surgery: An analysis of inpatient data
ConclusionsIn patients who underwent transsphenoidal pituitary surgery, OSA was associated with higher rates of certain pulmonary and airway complications. OSA was not associated with increased non–pulmonary/airway complications or inpatient mortality, despite older average age and higher comorbidity rates. Level of Evidence2C Laryngoscope, 2017
Source: The Laryngoscope - July 3, 2017 Category: ENT & OMF Authors: Sei Y. Chung, Michael J. Sylvester, Varesh R. Patel, Michael Zaki, Soly Baredes, James K. Liu, Jean Anderson Eloy Tags: Allergy/Rhinology Source Type: research

Balloon Eustachian tuboplasty under local anesthesia: Is it feasible?
ConclusionBET is a safe and feasible procedure under monitored anesthesia care, including local anesthesia along with sedation and analgesia. There is need for further methodological improvement to reduce pain and discomfort during the operation. Level of Evidence4. Laryngoscope, 2017
Source: The Laryngoscope - February 2, 2017 Category: ENT & OMF Authors: Veera Luukkainen, Ilkka Kivek äs, Sari Hammarén‐Malmi, Markus Rautiainen, Leena Pöyhönen, Antti A. Aarnisalo, Jussi Jero, Saku T. Sinkkonen Tags: Allergy/Rhinology Source Type: research

Preoperative β‐blockade and hypertension in the first hour of functional endoscopic sinus surgery
ConclusionsPreoperative β‐blocker use is an independent predictor of an exaggerated hypertensive response within the first hour of operative time. An exaggerated hypertensive effect should be anticipated in patients presenting for FESS with established pharmacologic β‐blockade, and caution should be applied to use of epinephrine‐containing solutions. Level of Evidence4. Laryngoscope, 2017
Source: The Laryngoscope - January 31, 2017 Category: ENT & OMF Authors: Samuel A. Schechtman, Aileen P. Wertz, Amy Shanks, Aleda Thompson, Kevin Tremper, Melissa A. Pynnonen, David W. Healy Tags: Allergy/Rhinology Source Type: research

Nasal versus tracheobronchial biopsies to diagnose primary ciliary dyskinesia: A meta ‐analysis
ConclusionTissue biopsy is one component of diagnosing PCD. We found no significant difference between biopsy sites in terms of obtaining an adequate ciliary sample for EM evaluation. This suggests that nasal biopsy should be preferred for patients old enough to tolerate an office biopsy without the need for general anesthesia. The merits of nasal versus tracheobronchial biopsy in the operating room depend more on the risks and benefits of the procedure being performed. Level of EvidenceNA Laryngoscope, 127:6–13, 2017
Source: The Laryngoscope - June 15, 2016 Category: ENT & OMF Authors: Eelam A. Adil, Kosuke Kawai, Natasha Dombrowski, Alexandria L. Irace, Michael J. Cunningham Tags: Allergy/Rhinology Source Type: research

Nasal versus tracheobronchial biopsies to diagnose primary ciliary dyskinesia: A meta‐analysis
ConclusionTissue biopsy is one component of diagnosing PCD. We found no significant difference between biopsy sites in terms of obtaining an adequate ciliary sample for EM evaluation. This suggests that nasal biopsy should be preferred for patients old enough to tolerate an office biopsy without the need for general anesthesia. The merits of nasal versus tracheobronchial biopsy in the operating room depend more on the risks and benefits of the procedure being performed. Level of EvidenceN/A. Laryngoscope, 2016
Source: The Laryngoscope - June 15, 2016 Category: ENT & OMF Authors: Eelam A. Adil, Kosuke Kawai, Natasha Dombrowski, Alexandria L. Irace, Michael J. Cunningham Tags: Allergy/Rhinology Source Type: research

Management of non‐invasive rhinosinusitis in the immunosuppressed patient population
ConclusionThis data indicates that surgical treatment provides improved outcomes for patients presenting with acute exacerbations of rhinosinusitis related to their immunocompromised state. Given the limited study population, these findings may not apply to HIV‐positive or ARS patients, and further study should be undertaken in these groups. Level of Evidence4. Laryngoscope, 2015
Source: The Laryngoscope - May 6, 2015 Category: ENT & OMF Authors: Ashley M. Dao, Shruthi K. Rereddy, Sarah K. Wise, John M. DelGaudio, Zara M. Patel Tags: Allergy/Rhinology Source Type: research

In‐office drainage of sinus Mucoceles: An alternative to operating‐room drainage
ConclusionsIn‐office drainage of sinus mucoceles is well tolerated by patients, with high success and low complication rates, even in large mucoceles with bone erosion. The presence of septations and neo‐osteogenesis reduce the likelihood of complete drainage and are relative contraindications. Orbital and skull base erosion are not contraindications. Level of Evidence4. Laryngoscope, 2014
Source: The Laryngoscope - November 24, 2014 Category: ENT & OMF Authors: Emily M. Barrow, John M. DelGaudio Tags: Allergy/Rhinology Source Type: research

Risk factors associated with severe and recurrent angioedema: An epidemic linked to ACE‐inhibitors
ConclusionsKnowledge of risk factors for severe and recurrent episodes of angioedema and improved education for both healthcare providers and patients, specifically related to ACEi use and allergy documentation, may significantly decrease the burden and morbidity of angioedema among high risk populations. Level of Evidence2b. Laryngoscope, 2014
Source: The Laryngoscope - June 17, 2014 Category: ENT & OMF Authors: Patricia A. Loftus, Melin Tan, Gunj Patel, Juan Lin, Sam Helman, Arvind Badhey, Eugenie Du, Richard V. Smith, Marvin P. Fried, Thomas J. Ow Tags: General Otolaryngology Source Type: research

The relationship between hypotension, cerebral flow, and the surgical field during endoscopic sinus surgery
ConclusionsHypotensive anesthesia is an effective method of controlling intraoperative bleeding during endoscopic sinus surgery; however the effect is clinically small in low MAP ranges. In otherwise healthy patients undergoing ESS with general anesthesia, reducing MAP to below 60 mm Hg may increase the risk of cerebral ischemia. Level of Evidence2b Laryngoscope, 2014
Source: The Laryngoscope - April 22, 2014 Category: ENT & OMF Authors: Thanh Ngoc Ha, Robert Graham van Renen, Guy L. Ludbrook, Rowan Valentine, Judy Ou, Peter‐John Wormald Tags: Allergy/Rhinology Source Type: research