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Source: Evidence-based Complementary and Alternative Medicine
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Total 81 results found since Jan 2013.
Retracted: Design and In Vitro Evaluation of Novel Cationic Lipids for siRNA Delivery in Breast Cancer Cell Lines
Evid Based Complement Alternat Med. 2023 Aug 2;2023:9892315. doi: 10.1155/2023/9892315. eCollection 2023.ABSTRACT[This retracts the article DOI: 10.1155/2022/9231641.].PMID:37565221 | PMC:PMC10412277 | DOI:10.1155/2023/9892315
Source: Evidence-based Complementary and Alternative Medicine - August 11, 2023 Category: Complementary Medicine Authors: Evidence-Based Complementary And Alternative Medicine Source Type: research
< em > δ < /em > -Opioid Receptor Activation Inhibits Ferroptosis by Activating the Nrf2 Pathway in MPTP-Induced Parkinson Disease Models
CONCLUSION: DORs exert neuroprotective effects in PD models by inhibiting ferroptosis partially via activating the Nrf2 pathway.PMID:36818224 | PMC:PMC9937764 | DOI:10.1155/2023/4130937
Source: Evidence-based Complementary and Alternative Medicine - February 23, 2023 Category: Complementary Medicine Authors: Benchi Cai Lifan Zhong Yanhui Liu Qian Xu Tao Chen Source Type: research
Knockdown of lncRNA < em > HOXD-AS2 < /em > Improves the Prognosis of Glioma Patients by Inhibiting the Proliferation and Migration of Glioma Cells
CONCLUSION: HOXD-AS2 is an oncogenic lncRNA associated with the poor prognosis of glioma. Knockdown of HOXD-AS2 may reduce the growth of glioma, which may provide a new avenue for treatment.PMID:36408341 | PMC:PMC9668444 | DOI:10.1155/2022/9337647
Source: Evidence-based Complementary and Alternative Medicine - November 21, 2022 Category: Complementary Medicine Authors: Feng Chen Ru-Ru Zhao Qian Li Zhen-Hua Chen Chun Luo Source Type: research
Deciphering the Pharmacological Mechanisms of Qidan Dihuang Decoction in Ameliorating Renal Fibrosis in Diabetic Nephropathy through Experimental Validation < em > In Vitro < /em > and < em > In Vivo < /em >
CONCLUSIONS: Taken together, our results suggest that QDD effectively alleviates diabetic renal injuries and fibrosis by inhibiting the PERK-eIF2α-ATF4 pathway and promoting autophagy in diabetic nephropathy.PMID:36091599 | PMC:PMC9463013 | DOI:10.1155/2022/4137578
Source: Evidence-based Complementary and Alternative Medicine - September 12, 2022 Category: Complementary Medicine Authors: Qiuer Liang Zhenyu Bai Ting Xie Hanqi Lu Lei Xiang Ke Ma Tianhao Liu Tingting Guo Liguo Chen Xiaoshan Zhao Ya Xiao Source Type: research
Long Noncoding RNA HLA Complex Group 18 Improves the Cell Proliferation of Myocardial Fibroblasts by Regulating the Hsa-microRNA-133a/Epidermal Growth Factor Receptor Axis
Evid Based Complement Alternat Med. 2022 Jul 31;2022:2668239. doi: 10.1155/2022/2668239. eCollection 2022.ABSTRACTHsa-microRNA (has-miR)-133a inactivates the extracellular signal-regulated kinase 1/2 (ERK1/2) pathway and suppresses the cell proliferation of myocardial fibroblasts by downregulation of the epidermal growth factor receptor (EGFR) expression. Bioinformatics analysis exhibits extended noncoding RNA HLA complex group 18 (lncRNA-HCG18) binds to hsa-miR-133a. The purpose of the current experiment is to explore whether lncRNA-HCG18 adsorbed hsa-miR-133a through sponging, resulting in decreased inhibition of hsa-miR...
Source: Evidence-based Complementary and Alternative Medicine - August 12, 2022 Category: Complementary Medicine Authors: Huoshun Shi Lebo Sun Dawei Zheng Guodong Xu Guofeng Shao Source Type: research
Curcumin Alleviates D-Galactose-Induced Cardiomyocyte Senescence by Promoting Autophagy via the SIRT1/AMPK/mTOR Pathway
Evid Based Complement Alternat Med. 2022 Jul 16;2022:2990843. doi: 10.1155/2022/2990843. eCollection 2022.ABSTRACTOxidative stress and impaired autophagy are the hallmarks of cardiac aging. However, there are no specific drugs available to prevent cardiac aging. Curcumin is a natural polyphenolic drug with antioxidant, antiaging, and autophagy-promoting effects. Here, we describe the preventive role of Curcumin in cardiac aging through the induction of autophagy and the restoration of autophagy via the SIRT1/AMPK/mTOR pathway. The number of cells positive for senescence-associated β-galactosidase, P53, P16, and intracellu...
Source: Evidence-based Complementary and Alternative Medicine - July 26, 2022 Category: Complementary Medicine Authors: Lei Yang Jun Shi Xiaowan Wang Rong Zhang Source Type: research
Network Pharmacology-Based Strategy to Investigate the Mechanisms of < em > Cibotium barometz < /em > in Treating Osteoarthritis
Evid Based Complement Alternat Med. 2022 Jul 14;2022:1826299. doi: 10.1155/2022/1826299. eCollection 2022.ABSTRACTCibotium barometz is a representative tonifying kidney drug and is widely used for osteoarthritis (OA) in traditional Chinese medicine. However, its regulatory mechanisms in treating OA remain to be sufficiently investigated. The main chemical components of Cibotium barometz were screened through the TCMID database and the corresponding targets were acquired through SwissTargetPrediction. The OA-related targets were obtained from the OMIM, Genecards, Genebank, TTD, and DisGeNET databases. The prediction of key ...
Source: Evidence-based Complementary and Alternative Medicine - July 25, 2022 Category: Complementary Medicine Authors: Guang-Yao Chen Yi-Fei Wang Xin-Bo Yu Xiao-Yu Liu Jia-Qi Chen Jing Luo Qing-Wen Tao Source Type: research
Cantharidin Inhibits Proliferation of Liver Cancer by Inducing DNA Damage via KDM4A-Dependent Histone H3K36 Demethylation
CONCLUSION: Cantharidin can inhibit the growth and promote apoptosis of hepatocellular carcinoma cells. Meanwhile, cantharidin can induce DNA damage in HCC cells. Mechanism studies have shown that cantharidin induces DNA damage through the demethylation of KDM4A-dependent histone H3K36.PMID:35860003 | PMC:PMC9293552 | DOI:10.1155/2022/2197071
Source: Evidence-based Complementary and Alternative Medicine - July 21, 2022 Category: Complementary Medicine Authors: Chao Wei Xiangui Deng Shudi Gao Xuemei Wan Jing Chen Source Type: research
