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CA1 contributes to microcalcification and tumourigenesis in breast cancer
Conclusion: The results of this study suggested that CA1 is a potential oncogene and that it contributes to abnormal cell calcification, apoptosis and migration in breast cancer.
Source: BMC Cancer - October 12, 2015 Category: Cancer & Oncology Authors: Yabing ZhengBing XuYan ZhaoHe GuChang LiYao WangXiaotian Chang Source Type: research

Cross-talk between alpha1D-adrenoceptors and transient receptor potential vanilloid type 1 triggers prostate cancer cell proliferation
Conclusions: We demonstrate a cross-talk between alpha1D-AR and TRPV1, that is involved in the control of PC3 cell proliferation. These data strongly support for a putative novel pharmacological approach in the treatment of PCa by targeting both alpha1D-AR and TRPV1 channels.
Source: BMC Cancer - December 7, 2014 Category: Cancer & Oncology Authors: Maria MorelliConsuelo AmantiniMassimo NabissiSonia LiberatiClaudio CardinaliValerio FarfarielloDaniele TomassoniWilma QuagliaAlessandro PiergentiliAlessandro BonifaziFabio Del BelloMatteo SantoniGabriele MammanaLucilla ServiAlessandra FilosaAngela Gismond Source Type: research