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10-year trends in statin utilization in Taiwan: a retrospective study using Taiwans National Health Insurance Research Database
Conclusion Atorvastatin was the most commonly used statin in Taiwan during 2002–2011. While patients with history of CVD were more likely to be prescribed higher intensity statins compared with those without, this difference was not found comparing those with and without diabetes.
Source: BMJ Open - May 17, 2017 Category: General Medicine Authors: Hsieh, H.-C., Hsu, J. C., Lu, C. Y. Tags: Open access, Evidence based practice Research Source Type: research

Interpretation of the evidence for the efficacy and safety of statin therapy
Publication date: Available online 8 September 2016 Source:The Lancet Author(s): Rory Collins, Christina Reith, Jonathan Emberson, Jane Armitage, Colin Baigent, Lisa Blackwell, Roger Blumenthal, John Danesh, George Davey Smith, David DeMets, Stephen Evans, Malcolm Law, Stephen MacMahon, Seth Martin, Bruce Neal, Neil Poulter, David Preiss, Paul Ridker, Ian Roberts, Anthony Rodgers, Peter Sandercock, Kenneth Schulz, Peter Sever, John Simes, Liam Smeeth, Nicholas Wald, Salim Yusuf, Richard Peto This Review is intended to help clinicians, patients, and the public make informed decisions about statin therapy for the prevention...
Source: The Lancet - September 8, 2016 Category: Journals (General) Source Type: research

Clinical Picture Immune-mediated necrotising myopathy linked to statin use
In December, 2013, a 59-year-old man presented to the Neurology Department with progressive pelvic girdle myalgia and proximal weakness so severe that he needed help walking. His myalgia had started in March, 2012, 4 months after starting atorvastatin, and had persisted despite discontinuation of the statin in September, 2013. On examination we noted severe proximal paraparesis. Laboratory tests revealed substantially raised serum creatine kinase concentration (3453 U/L, normal range
Source: LANCET - June 11, 2015 Category: Journals (General) Authors: Stefan Kipfer, Susanna Frigerio, Jürgen Hench, Audrey Aussy, Olivier Boyer Tags: Clinical Picture Source Type: research

Statin-Associated Polymyositis Following Omeprazole Treatment.
Abstract Statins are an extensively used class of drugs, and myopathy is an uncommon, but well-described side effect of statin therapy. Inflammatory myopathies, including polymyositis, dermatomyositis, and necrotizing autoimmune myopathy, are even rarer, but debilitating, side effects of statin therapy that are characterized by the persistence of symptoms even after discontinuation of the drug. It is important to differentiate statin-associated inflammatory myopathies from other self-limited myopathies, as the disease often requires multiple immunosuppressive therapies. Drug interactions increase the risk of stati...
Source: Clinical Medicine and Research - April 12, 2013 Category: Journals (General) Authors: Kanth R, Shah MS, Flores RM Tags: Clin Med Res Source Type: research