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Drug: Insulin

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Short period-administration of myo-inositol and metformin on hormonal and glycolipid profiles in patients with polycystic ovary syndrome: a systematic review and updated meta-analysis of randomized controlled trials
CONCLUSIONS: Compared with metformin, the suitable supplemental dosage of myo-ins may be helpful in lowering levels of TG and avoiding adverse events (AEs).PMID:35363325 | DOI:10.26355/eurrev_202203_28322
Source: European Review for Medical and Pharmacological Sciences - April 1, 2022 Category: Drugs & Pharmacology Authors: J-Q Zhang C Xing B He Source Type: research

Why are women with polycystic ovary syndrome obese?
AbstractIntroductionPolycystic ovary syndrome (PCOS) is a common condition characterized by reproductive, hyperandrogenic and dysmetabolic features, and often becomes clinically manifest during adolescence, particularly with weight-gain.Sources of dataPubmed search.Areas of agreementPCOS is heritable and closely associates with obesity (based on data from both epidemiological and genetic studies). Furthermore, insulin resistance forms a central cornerstone of the pathogenesis of PCOS and mediates a close association between obesity and the severity of the phenotypic features of PCOS.Areas of controversyOur understanding of...
Source: British Medical Bulletin - March 12, 2022 Category: General Medicine Source Type: research