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Antimicrobial resistance genes and genetic characteristics of multidrug-resistant < em > Escherichia coli < /em > in a veterinary hospital in Taiwan
Conclusion. This study showed a high diversity of antimicrobial resistance genes and genotypes among MDR E. coli isolated from diseased livestock in Taiwan. To our knowledge, this is the first report of plasmid-mediated ESBL in FOX-3 β-lactamase-producing E. coli isolates in Taiwan. MDR E. coli isolates from animal origins may contaminate the environment, resulting in public health concerns, indicating that MDR isolates from animals need to be continuously investigated.PMID:34779761 | DOI:10.1099/jmm.0.001453
Source: Journal of Medical Microbiology - November 15, 2021 Category: Microbiology Authors: Lii-Tzu Wu Xin-Xia Wu Se-Chin Ke Yi-Pei Lin Ying-Chen Wu Ter-Hsin Chen Chih-Ming Chen Source Type: research

Machine learning for identifying resistance features of < em > Klebsiella pneumoniae < /em > using whole-genome sequence single nucleotide polymorphisms
Conclusion. Machine learning methods can effectively be used to predict resistance genes and associated SNPs. The FFS and CMD algorithms have wide applicability. They can be used for the drug-resistance analysis of any microorganism with genomic variation and phenotypic data. This work lays a foundation for resistance research in clinical applications.PMID:34812714 | DOI:10.1099/jmm.0.001474
Source: Journal of Medical Microbiology - November 23, 2021 Category: Microbiology Authors: Wenjia Liu Nanjiao Ying Qiusi Mo Shanshan Li Mengjie Shao Lingli Sun Lei Zhu Source Type: research

Antimicrobial resistance genes and genetic characteristics of multidrug-resistant < em > Escherichia coli < /em > in a veterinary hospital in Taiwan
Conclusion. This study showed a high diversity of antimicrobial resistance genes and genotypes among MDR E. coli isolated from diseased livestock in Taiwan. To our knowledge, this is the first report of plasmid-mediated ESBL in FOX-3 β-lactamase-producing E. coli isolates in Taiwan. MDR E. coli isolates from animal origins may contaminate the environment, resulting in public health concerns, indicating that MDR isolates from animals need to be continuously investigated.PMID:34779761 | DOI:10.1099/jmm.0.001453
Source: Journal of Medical Microbiology - November 15, 2021 Category: Microbiology Authors: Lii-Tzu Wu Xin-Xia Wu Se-Chin Ke Yi-Pei Lin Ying-Chen Wu Ter-Hsin Chen Chih-Ming Chen Source Type: research

Machine learning for identifying resistance features of < em > Klebsiella pneumoniae < /em > using whole-genome sequence single nucleotide polymorphisms
Conclusion. Machine learning methods can effectively be used to predict resistance genes and associated SNPs. The FFS and CMD algorithms have wide applicability. They can be used for the drug-resistance analysis of any microorganism with genomic variation and phenotypic data. This work lays a foundation for resistance research in clinical applications.PMID:34812714 | DOI:10.1099/jmm.0.001474
Source: Journal of Medical Microbiology - November 23, 2021 Category: Microbiology Authors: Wenjia Liu Nanjiao Ying Qiusi Mo Shanshan Li Mengjie Shao Lingli Sun Lei Zhu Source Type: research

Antibiotic resistance among clinical < em > Ureaplasma < /em > isolates from Cuban individuals between 2013 and 2018
Conclusions. Although low levels of antibiotic resistance were detected in Cuban patients over a 5-year period, continued surveillance of the antibiotic susceptibility of Ureaplasma is necessary to monitor possible changes in resistance patterns.PMID:35175912 | DOI:10.1099/jmm.0.001477
Source: Journal of Medical Microbiology - February 17, 2022 Category: Microbiology Authors: Nadia Mar ía Rodríguez Preval Owen B Spiller Brian A Mondeja Rodr íguez Ruxana Sardi ñas Morales Yenis Ram írez Cintra Jos é A Rivera-Tapia Source Type: research

First identification of < em > bla < /em > < sub > NDM-5 < /sub > producing < em > Escherichia coli < /em > from neonates and a HIV infected adult in Tanzania
Conclusion. This is the first report, to our knowledge, from Tanzania detecting bla NDM-5 producing E. coli. The carbapenemase gene was carried on an IncFIA and IncX3 type plasmids. Our findings highlight the urgent need for a robust antimicrobial resistance (AMR) surveillance system to monitor and rapidly report on the incidence and spread of emerging resistant bacteria in Tanzania.PMID:35225760 | DOI:10.1099/jmm.0.001513
Source: Journal of Medical Microbiology - February 28, 2022 Category: Microbiology Authors: Joel Manyahi Sabrina J Moyo Upendo Kibwana Richard N Goodman Ellie Allman Alasdair T M Hubbard Bj ørn Blomberg Nina Langeland Adam P Roberts Source Type: research

< em > In vitro < /em > evaluation of antibiotic synergy for carbapenem-resistant < em > Klebsiella pneumoniae < /em > clinical isolates
CONCLUSIONS: Of the three combinations tested, imipenem and tigecycline followed by meropenem-colistin were found to be best. No synergy was detected for levofloxacin-polymyxin B combination.PMID:35345078 | DOI:10.4103/ijmr.IJMR_760_19
Source: The Indian Journal of Medical Research - March 28, 2022 Category: Biomedical Science Authors: Anku Goel Varsha Gupta Lipika Singhal Sanjeev Palta Jagdish Chander Source Type: research