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Drug: Estradiol

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Total 7339 results found since Jan 2013.

Serum estradiol level predicts acute kidney injury in medical intensive care unit patients
AbstractPrevious studies have shown that serum estradiol (E2) levels can predict mortality in intensive care unit patients. Our study investigated the predictive role of admission estradiol level on patient mortality and development of acute kidney injury in medical intensive care unit patients with a wide range of diagnoses. We conducted a prospective cohort study using serum samples from hospitalized patients in medical, cardiac, and pulmonary intensive care units at the Ege University Hospital within 6 months. Serum estradiol levels from 118 adult patients were collected within 48  h of hospitalization. Receiver operat...
Source: Internal and Emergency Medicine - August 27, 2022 Category: Emergency Medicine Source Type: research

Medical treatment of ureteral obstruction associated with ovarian remnants and/or endometriosis: report of 3 cases and review of the literature
Conclusions Low dose intermittent danazol or GnRH-a alone or with add-back, may be effective long-term therapies in endometriosis-associated ureteral obstruction when surgery is contraindicated, refused or difficult to perform.
Source: Journal of Minimally Invasive Gynecology - December 20, 2014 Category: OBGYN Source Type: research

The role of microRNAs on angiogenesis and vascular pressure in preeclampsia: The evidence from systematic review
Conclusion Data confirm that miRNAs are involved in pathobiology of preeclampsia including interference with angiogenesis during pre-clinical stage and induction of vascular resistance and vasoconstriction in clinical stage.
Source: Egyptian Journal of Medical Human Genetics - April 29, 2015 Category: Genetics & Stem Cells Source Type: research

Estradiol activates ERK phosphorylation by binding to ER β to inhibit proliferation and promote apoptosis of human chondrocytes
Nan Fang Yi Ke Da Xue Xue Bao. 2021 Mar 25;41(3):336-343. doi: 10.12122/j.issn.1673-4254.2021.03.04.ABSTRACTOBJECTIVE: To explore the effect of estradiol (E2) binding to its receptor ERβ on the proliferation and apoptosis of C28I2 cells.OBJECTIVE: We cloned the sequence of ESR2 into a recombinant adenovirus plasmid (pAd-ESR2) and packaged the plasmid in HEK293 cells. Normal human chondrocyte C28I2 cells were transfected with Ad-ESR2 or small interfering RNA targeting ESR2-siRNA (ESR2-siRNA), and the effects of treatment with DMSO or E2 on the expression of the proteins associated with endoplasmic reticulum (ER) stress and...
Source: Journal of Southern Medical University - April 14, 2021 Category: Universities & Medical Training Authors: M Zhang Y Yang M Liu L Liang R Luo D Yin F Guo Source Type: research

Electroacupuncture for the treatment of perimenopausal syndrome: a systematic review and meta-analysis of randomized controlled trials
CONCLUSION: The effect of EA appeared broadly similar to HT and MA in the treatment of PMS, although EA-associated reductions in KI were superior to MA and sham EA, suggesting effects beyond placebo. The evidence base is limited by a small number of eligible studies, risk of bias and clinical/statistical heterogeneity, limiting our ability to draw firm conclusions. As such, additional larger scale, high-quality RCTs are needed.PMID:34753328 | DOI:10.1177/09645284211055742
Source: Acupuncture in Medicine : journal of the British Medical Acupuncture Society - November 10, 2021 Category: Complementary Medicine Authors: Zhiyan Zhong Haoxu Dong Hui Wang Yao Huang Dongmei Huang Guangying Huang Source Type: research